AU779702B2 - New isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

New isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them Download PDF

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Publication number
AU779702B2
AU779702B2 AU23242/02A AU2324202A AU779702B2 AU 779702 B2 AU779702 B2 AU 779702B2 AU 23242/02 A AU23242/02 A AU 23242/02A AU 2324202 A AU2324202 A AU 2324202A AU 779702 B2 AU779702 B2 AU 779702B2
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Australia
Prior art keywords
disorders
group
compound
formula
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU23242/02A
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English (en)
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AU2324202A (en
Inventor
Marie-Francoise Boussard
Jean-Albert Boutin
Philippe Delagrange
Anne Rousseau
Michel Wierzbicki
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Les Laboratoires Servier SAS
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Les Laboratoires Servier SAS
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Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Publication of AU2324202A publication Critical patent/AU2324202A/en
Application granted granted Critical
Publication of AU779702B2 publication Critical patent/AU779702B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU23242/02A 2001-03-12 2002-03-12 New isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them Ceased AU779702B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0103293 2001-03-12
FR0103293A FR2821843B1 (fr) 2001-03-12 2001-03-12 Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
AU2324202A AU2324202A (en) 2002-09-19
AU779702B2 true AU779702B2 (en) 2005-02-10

Family

ID=8860976

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23242/02A Ceased AU779702B2 (en) 2001-03-12 2002-03-12 New isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (1) US6465660B1 (show.php)
EP (1) EP1241169B1 (show.php)
JP (1) JP3842151B2 (show.php)
KR (1) KR100450313B1 (show.php)
CN (1) CN1159316C (show.php)
AR (1) AR034583A1 (show.php)
AT (1) ATE248171T1 (show.php)
AU (1) AU779702B2 (show.php)
BR (1) BR0200721A (show.php)
CA (1) CA2376876C (show.php)
DE (1) DE60200023T2 (show.php)
DK (1) DK1241169T3 (show.php)
EA (1) EA004035B1 (show.php)
ES (1) ES2206438T3 (show.php)
FR (1) FR2821843B1 (show.php)
HK (1) HK1049000B (show.php)
HU (1) HUP0200913A3 (show.php)
MX (1) MXPA02002601A (show.php)
NO (1) NO20021198L (show.php)
NZ (1) NZ517742A (show.php)
PL (1) PL352750A1 (show.php)
PT (1) PT1241169E (show.php)
SI (1) SI1241169T1 (show.php)
ZA (1) ZA200202030B (show.php)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PT1517909E (pt) * 2002-06-21 2007-01-31 Suven Life Sciences Ltd Novos arilcarbonilindoles tetracíclicos que possuem afinidade para o receptor de serotonina, úteis como agentes terapêuticos, processo para a sua preparação e composições farmacêuticas que os contêm
CA2490115C (en) * 2002-06-21 2009-09-01 Suven Life Sciences Limited Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
EP1567492B1 (en) * 2002-11-28 2013-05-22 Suven Life Sciences Limited N-arylsulfonyl-3-aminoalkoxyindoles
KR100739987B1 (ko) * 2002-12-18 2007-07-16 수벤 라이프 사이언시스 리미티드 세로토닌 수용체 친화력을 가지는 테트라사이클릭 3-치환인돌
RU2387655C2 (ru) * 2004-08-09 2010-04-27 Бристол-Маерс Сквибб Компани Ингибиторы репликации вируса гепатита с
ES2580702B1 (es) 2015-02-25 2017-06-08 Palobiofarma, S.L. Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina
US20240090802A1 (en) 2022-09-02 2024-03-21 Dexcom, Inc. Continuous analyte sensor devices and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5377098A (en) * 1976-12-16 1978-07-08 Sumitomo Chem Co Ltd Preparation of indoloisoquinoline derivative
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US5441955A (en) * 1993-11-19 1995-08-15 Pathogenesis Corporation Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof
FR2743365A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa Derives de 5h,10h-imidazo(1,2-a)indolo(3,2-e)pyrazine-4-one, leur preparation et les medicaments les contenant
WO2002000215A1 (en) * 2000-06-23 2002-01-03 Cognetix, Inc. Subtype selective melatonergics

Also Published As

Publication number Publication date
CN1159316C (zh) 2004-07-28
JP3842151B2 (ja) 2006-11-08
DK1241169T3 (da) 2003-11-24
ZA200202030B (en) 2002-10-03
NO20021198D0 (no) 2002-03-11
HUP0200913A2 (hu) 2002-11-28
ES2206438T3 (es) 2004-05-16
DE60200023T2 (de) 2004-06-03
DE60200023D1 (de) 2003-10-02
FR2821843B1 (fr) 2003-05-09
AR034583A1 (es) 2004-03-03
ATE248171T1 (de) 2003-09-15
JP2002265469A (ja) 2002-09-18
AU2324202A (en) 2002-09-19
HUP0200913A3 (en) 2004-11-29
HK1049000B (zh) 2005-01-07
NZ517742A (en) 2003-02-28
CA2376876A1 (fr) 2002-09-12
CA2376876C (fr) 2006-07-11
KR20020072782A (ko) 2002-09-18
CN1375494A (zh) 2002-10-23
EP1241169A1 (fr) 2002-09-18
NO20021198L (no) 2002-09-13
MXPA02002601A (es) 2004-11-12
PT1241169E (pt) 2003-11-28
PL352750A1 (en) 2002-09-23
HU0200913D0 (show.php) 2002-05-29
US6465660B1 (en) 2002-10-15
KR100450313B1 (ko) 2004-09-30
BR0200721A (pt) 2002-12-03
FR2821843A1 (fr) 2002-09-13
EA004035B1 (ru) 2003-12-25
SI1241169T1 (en) 2003-12-31
HK1049000A1 (en) 2003-04-25
EA200200241A1 (ru) 2002-10-31
EP1241169B1 (fr) 2003-08-27

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