AU774432B2 - Multiple domain glycoprotein hormones and methods of using - Google Patents

Multiple domain glycoprotein hormones and methods of using Download PDF

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Publication number
AU774432B2
AU774432B2 AU11072/00A AU1107200A AU774432B2 AU 774432 B2 AU774432 B2 AU 774432B2 AU 11072/00 A AU11072/00 A AU 11072/00A AU 1107200 A AU1107200 A AU 1107200A AU 774432 B2 AU774432 B2 AU 774432B2
Authority
AU
Australia
Prior art keywords
activity
fsh
composition
confers
subunit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU11072/00A
Other languages
English (en)
Other versions
AU1107200A (en
Inventor
David Ben-Menahem
Irving Boime
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington University in St Louis WUSTL
Original Assignee
University of Washington
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, Washington University in St Louis WUSTL filed Critical University of Washington
Publication of AU1107200A publication Critical patent/AU1107200A/en
Application granted granted Critical
Publication of AU774432B2 publication Critical patent/AU774432B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU11072/00A 1998-10-19 1999-10-12 Multiple domain glycoprotein hormones and methods of using Ceased AU774432B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/175,017 US6635256B1 (en) 1998-10-19 1998-10-19 Glycoprotein hormone compositions comprising two β subunits and methods of use thereof
US09/175017 1998-10-19
PCT/US1999/023555 WO2000023473A1 (en) 1998-10-19 1999-10-12 Multiple domain glycoprotein hormones and methods of using

Publications (2)

Publication Number Publication Date
AU1107200A AU1107200A (en) 2000-05-08
AU774432B2 true AU774432B2 (en) 2004-06-24

Family

ID=22638493

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11072/00A Ceased AU774432B2 (en) 1998-10-19 1999-10-12 Multiple domain glycoprotein hormones and methods of using

Country Status (15)

Country Link
US (2) US6635256B1 (https=)
EP (1) EP1123315A1 (https=)
JP (1) JP2002533300A (https=)
KR (1) KR20010092418A (https=)
CN (1) CN1330665A (https=)
AU (1) AU774432B2 (https=)
BR (1) BR9914670A (https=)
CA (1) CA2347062A1 (https=)
CZ (1) CZ20011388A3 (https=)
HU (1) HUP0103760A3 (https=)
IL (1) IL142681A0 (https=)
NO (1) NO20011925L (https=)
PL (1) PL347375A1 (https=)
TR (1) TR200101463T2 (https=)
WO (1) WO2000023473A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001333772A (ja) 2000-04-25 2001-12-04 Washington Univ 可変性の活性を有する単鎖稔性ホルモン
AU2001255624A1 (en) * 2000-04-25 2001-11-07 Washington University Single-chain fertility hormones with variable lh activity
AU2001283319A1 (en) * 2000-08-11 2002-02-25 Applied Research Systems Ars Holding N.V. Glycoproteins and methods of use thereof
US6987172B2 (en) * 2001-03-05 2006-01-17 Washington University In St. Louis Multifunctional single chain glycoprotein hormones comprising three or more β subunits
US7081446B2 (en) * 2002-01-31 2006-07-25 The Trustees Of Columbia University In The City Of New York Long-acting follicle stimulating hormone analogues and uses thereof
DE602004030546D1 (de) 2003-03-04 2011-01-27 Aspenbio Pharma Inc LH zur Verwendung der Erhaltung einer oder mehreren Schwangerschaften durch Induktion der Bildung des sekundären Gelbkörpers.
JP4412989B2 (ja) * 2003-12-15 2010-02-10 株式会社日立製作所 複数の記憶システムを有するデータ処理システム
US20080039372A1 (en) * 2005-07-21 2008-02-14 The Trustees Of Columbia University In The City Of New York Human chorionic gonadotropin antagonists and methods to prevent ovarian hyperstimulation
US9707276B2 (en) 2012-12-03 2017-07-18 Merck Sharp & Dohme Corp. O-glycosylated carboxy terminal portion (CTP) peptide-based insulin and insulin analogues
EP2968391A1 (en) 2013-03-13 2016-01-20 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CA3140267A1 (en) 2019-05-16 2020-11-19 Ceva Sante Animale Compositions and methods for increasing reproduction performance in non-human mammals using recombinant luteinizing hormone

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839831A2 (en) * 1994-02-18 1998-05-06 Sensi-Test Single chain gonadotropin
WO1999025849A1 (en) * 1997-11-17 1999-05-27 Washington University Single-chain bifunctional glycoprotein hormones

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0578328B1 (en) 1983-11-02 1999-12-29 Applied Research Systems ARS Holding N.V. Material and methods for the production of a heterodimeric human LH with a Met42 Val55 alpha subunit
CA1213537A (en) 1984-05-01 1986-11-04 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Polypeptide expression method
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
ES2098261T3 (es) 1989-02-21 1997-05-01 Univ Washington Formas modificadas de hormonas reproductoras.
WO1991016922A1 (en) 1990-05-08 1991-11-14 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered immunological characteristics, efficacy and/or receptor specificity
CA2097291A1 (en) * 1990-12-13 1992-06-14 David P. Gearing Leukemia inhibitory factor receptors
WO1992022568A1 (en) * 1991-06-18 1992-12-23 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
ZA942206B (en) * 1993-04-01 1994-10-31 Amgen Inc Biologically active polypeptide fusion dimers
PT725795E (pt) * 1994-08-12 2004-05-31 Univ Washington Formas de cadeia simples do quarteto de hormonas glicoproteicas

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839831A2 (en) * 1994-02-18 1998-05-06 Sensi-Test Single chain gonadotropin
WO1999025849A1 (en) * 1997-11-17 1999-05-27 Washington University Single-chain bifunctional glycoprotein hormones

Also Published As

Publication number Publication date
NO20011925D0 (no) 2001-04-19
US6635256B1 (en) 2003-10-21
PL347375A1 (en) 2002-04-08
TR200101463T2 (tr) 2001-10-22
JP2002533300A (ja) 2002-10-08
HUP0103760A2 (hu) 2002-01-28
US20040220088A1 (en) 2004-11-04
NO20011925L (no) 2001-06-18
EP1123315A1 (en) 2001-08-16
WO2000023473A1 (en) 2000-04-27
KR20010092418A (ko) 2001-10-24
HUP0103760A3 (en) 2003-09-29
US7442376B2 (en) 2008-10-28
CZ20011388A3 (cs) 2001-10-17
AU1107200A (en) 2000-05-08
BR9914670A (pt) 2002-02-05
IL142681A0 (en) 2002-03-10
CA2347062A1 (en) 2000-04-27
CN1330665A (zh) 2002-01-09

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FGA Letters patent sealed or granted (standard patent)