AU772167B2 - Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs - Google Patents

Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs Download PDF

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Publication number
AU772167B2
AU772167B2 AU62766/00A AU6276600A AU772167B2 AU 772167 B2 AU772167 B2 AU 772167B2 AU 62766/00 A AU62766/00 A AU 62766/00A AU 6276600 A AU6276600 A AU 6276600A AU 772167 B2 AU772167 B2 AU 772167B2
Authority
AU
Australia
Prior art keywords
gly
orn
polypeptide
dendrimer
dendrimers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU62766/00A
Other languages
English (en)
Other versions
AU6276600A (en
Inventor
Antonio Verdini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of AU6276600A publication Critical patent/AU6276600A/en
Application granted granted Critical
Publication of AU772167B2 publication Critical patent/AU772167B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/641Branched, dendritic or hypercomb peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU62766/00A 1999-07-23 2000-07-21 Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs Ceased AU772167B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999FO000015A ITFO990015A1 (it) 1999-07-23 1999-07-23 "dendrimeri polipeptidici quali trasportatori unimolecolari di farmaci e sostanze biologicamente attive".
ITFO99A000015 1999-07-23
PCT/EP2000/007022 WO2001007469A2 (fr) 1999-07-23 2000-07-21 Dendrimeres polypeptidiques en tant que porteurs unimoleculaires d'agents de contraste d'imagerie diagnostique, de substances bioactives et de medicaments

Publications (2)

Publication Number Publication Date
AU6276600A AU6276600A (en) 2001-02-13
AU772167B2 true AU772167B2 (en) 2004-04-08

Family

ID=11353680

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62766/00A Ceased AU772167B2 (en) 1999-07-23 2000-07-21 Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs

Country Status (12)

Country Link
EP (1) EP1200461A2 (fr)
JP (1) JP2003506326A (fr)
CN (1) CN1364171A (fr)
AU (1) AU772167B2 (fr)
CA (1) CA2380178A1 (fr)
HU (1) HUP0201975A3 (fr)
IT (1) ITFO990015A1 (fr)
NO (1) NO20020333D0 (fr)
NZ (1) NZ517231A (fr)
PL (1) PL353273A1 (fr)
WO (1) WO2001007469A2 (fr)
ZA (1) ZA200201089B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR032941A1 (es) 2001-03-05 2003-12-03 Shell Int Research Un procedimiento para preparar un aceite base lubricante y aceite base obtenido, con sus diversas utilizaciones
MY137259A (en) 2001-03-05 2009-01-30 Shell Int Research Process to prepare a lubricating base oil and a gas oil.
AR032930A1 (es) 2001-03-05 2003-12-03 Shell Int Research Procedimiento para preparar un aceite de base lubricante y gas oil
CN1558777A (zh) * 2001-10-29 2004-12-29 �Ϻ���ͨ��ѧ 抗肿瘤的树枝状聚合物药物释放系统
WO2004009739A2 (fr) 2002-07-18 2004-01-29 Shell Internationale Research Maatschappij B.V. Procede de preparation d'une cire microcristalline et d'un combustible de distillat moyen
EP1525890A1 (fr) 2003-10-02 2005-04-27 Complex Biosystems GmbH Complexes protéine-protéophore
EP2676691B1 (fr) 2005-11-17 2016-07-06 Zogenix, Inc. Administration de préparations visqueuses par injection sans aiguille
HUP0700782A3 (en) * 2007-12-05 2009-11-30 Biostatin Gyogyszerkutato Fejl Novel peptides and amino acid derivatives, pharmaceutical compositions containing the same and use of the compounds
AU2009241847B2 (en) 2008-04-28 2014-07-10 Zogenix, Inc. Novel formulations for treatment of migraine
AU2009279365A1 (en) * 2008-08-05 2010-02-11 The University Of Queensland Antigen-presenting scaffolds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000540A1 (fr) * 1993-06-18 1995-01-05 Robert Webber Vecteur et immunogene de synthese

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1246059A (zh) * 1997-01-29 2000-03-01 奈科姆成像有限公司 聚合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000540A1 (fr) * 1993-06-18 1995-01-05 Robert Webber Vecteur et immunogene de synthese

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HUANG E A, MOL. IMMUNOL. 1994, VOL. 31 NO.15, PP 1191-1199 *

Also Published As

Publication number Publication date
CN1364171A (zh) 2002-08-14
WO2001007469A2 (fr) 2001-02-01
NO20020333L (no) 2002-01-22
NZ517231A (en) 2003-05-30
JP2003506326A (ja) 2003-02-18
EP1200461A2 (fr) 2002-05-02
HUP0201975A2 (en) 2002-10-28
WO2001007469A3 (fr) 2001-05-10
ITFO990015A1 (it) 2001-01-23
HUP0201975A3 (en) 2002-11-28
PL353273A1 (en) 2003-11-03
CA2380178A1 (fr) 2001-02-01
ZA200201089B (en) 2003-07-30
AU6276600A (en) 2001-02-13
NO20020333D0 (no) 2002-01-22

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FGA Letters patent sealed or granted (standard patent)