AU772105B2 - Homer interacting proteins - Google Patents

Homer interacting proteins Download PDF

Info

Publication number
AU772105B2
AU772105B2 AU57798/99A AU5779899A AU772105B2 AU 772105 B2 AU772105 B2 AU 772105B2 AU 57798/99 A AU57798/99 A AU 57798/99A AU 5779899 A AU5779899 A AU 5779899A AU 772105 B2 AU772105 B2 AU 772105B2
Authority
AU
Australia
Prior art keywords
homer
cell
protein
compound
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU57798/99A
Other languages
English (en)
Other versions
AU5779899A (en
Inventor
Jutta Beneken
Anthony A. Lanahan
Daniel Leahy
Jian Cheng Tu
Paul F. Worley
Bo Xiao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
School of Medicine of Johns Hopkins University
Original Assignee
Johns Hopkins University
School of Medicine of Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University, School of Medicine of Johns Hopkins University filed Critical Johns Hopkins University
Publication of AU5779899A publication Critical patent/AU5779899A/en
Application granted granted Critical
Publication of AU772105B2 publication Critical patent/AU772105B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU57798/99A 1998-08-18 1999-08-18 Homer interacting proteins Ceased AU772105B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US9733498P 1998-08-18 1998-08-18
US60/097334 1998-08-18
US13849499P 1999-06-09 1999-06-09
US13849399P 1999-06-09 1999-06-09
US13842699P 1999-06-09 1999-06-09
US60/138494 1999-06-10
US60/138493 1999-06-10
US60/138426 1999-06-10
PCT/US1999/018973 WO2000011204A2 (fr) 1998-08-18 1999-08-18 Proteines a interaction de la famille homer

Publications (2)

Publication Number Publication Date
AU5779899A AU5779899A (en) 2000-03-14
AU772105B2 true AU772105B2 (en) 2004-04-08

Family

ID=27492912

Family Applications (1)

Application Number Title Priority Date Filing Date
AU57798/99A Ceased AU772105B2 (en) 1998-08-18 1999-08-18 Homer interacting proteins

Country Status (4)

Country Link
EP (1) EP1105734A4 (fr)
JP (1) JP2002523056A (fr)
AU (1) AU772105B2 (fr)
WO (1) WO2000011204A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
WO2003056329A2 (fr) * 2001-12-21 2003-07-10 7Tm Pharma A/S Utilisation d'un complexe de transduction de signal dans des processus de mise au point de medicaments
AU2003287918A1 (en) 2002-12-20 2004-07-14 Enkam Pharmaceuticals A/S Method of modulation of interaction between receptor and ligand
DE102006030366A1 (de) * 2006-06-27 2008-01-03 Universität Rostock Pharmazeutisches Mittel zur Behandlung des Parkinson-Syndroms und ein Verfahren zum Screening von Substanzen zur Verminderung der Parkinson-Symptomatik
WO2009143622A1 (fr) * 2008-05-29 2009-12-03 Chum Méthodes de stratification, de pronostic et de diagnostic de la schizophrénie, molécules d’acide nucléique mutantes et polypeptides
CN108004214B (zh) * 2017-11-29 2020-10-13 武汉大学 Homer2单克隆抗体及其应用
CN111141912A (zh) * 2020-03-02 2020-05-12 南通大学 Gabarap与optn结合在optn蓄积导致的神经元病变中的作用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ240921A (en) * 1990-12-12 1994-06-27 Zymogenetics Inc G protein coupled glutamate receptor (neurotransmitters), recombinant production
US6084084A (en) * 1996-02-21 2000-07-04 Nps Pharmaceuticals, Inc. Human metabotropic glutamate receptor

Also Published As

Publication number Publication date
WO2000011204A2 (fr) 2000-03-02
AU5779899A (en) 2000-03-14
JP2002523056A (ja) 2002-07-30
EP1105734A4 (fr) 2005-04-13
WO2000011204A3 (fr) 2001-02-15
EP1105734A2 (fr) 2001-06-13

Similar Documents

Publication Publication Date Title
US6864083B2 (en) Nucleic acid molecule encoding homer 2a protein
ES2298226T3 (es) Polipeptidos relacionados con wnt-1, y acidos nucleicos que los codifican.
JP2002525115A (ja) 発作、高血圧、糖尿病および肥満を予報および治療する、遺伝子およびタンパク質
AU772105B2 (en) Homer interacting proteins
JP2008506707A (ja) てんかんの診断および治療のための組成物ならびに方法
US20050059120A1 (en) Compositions, methods, and kits relating to resistin-like molecules
CA2568201A1 (fr) Identification d'un transporteur d'ergothioneine et ses utilisations therapeutiques
EP1662255A2 (fr) Protéines interagissant avec Homer
GB2411403A (en) Transgenic animals with altered NCS-1 expression
WO1998041541A9 (fr) Utilisations therapeutiques de molecules de proteines grip et apparentees a grip
CA2405311A1 (fr) Matiere biologique et utilisations de celle-ci
WO2003003013A1 (fr) Effets non nucleaires d'hormone thyroidienne
WO2001096371A2 (fr) Gene lie a l'adipose
US20020010944A1 (en) CeSERT genes, proteins, and modulatory compounds
WO2000078921A2 (fr) Proteines de shank et leur procede d'utilisation
US20090312245A1 (en) SRA binding protein
WO1999027088A2 (fr) Nouveaux gene et proteine exprimes dans les tissus nerveux et pancreatiques
JP4488720B2 (ja) アポトーシス関連蛋白質およびその用途
US20030104443A1 (en) AFAP sequences, polypeptides, antibodies and methods
WO2006007375A2 (fr) Utilisation de bridge-1 et activateurs et inhibiteurs de ceux-ci utilises dans le traitement du diabete insulino-dependant
KR20060129263A (ko) 분비된 신경 아폽토시스 억제 단백질
US20050233956A1 (en) Proteins involved in the regulation of energy homeostasis
US7374890B2 (en) Methods for identifying compounds that modulate ΔTRα2 activity
JP2005521424A (ja) 新規パンコルチン−パブロ蛋白相互作用およびそれらの使用方法
US20050119206A1 (en) Cg8327, cg10823, cg18418, cg15862, cg3768, cg11447 and cg16750 homologous proteins involved in the regulation of energy homeostasis

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)