AU769471B2 - Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium - Google Patents

Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium Download PDF

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Publication number
AU769471B2
AU769471B2 AU24120/00A AU2412000A AU769471B2 AU 769471 B2 AU769471 B2 AU 769471B2 AU 24120/00 A AU24120/00 A AU 24120/00A AU 2412000 A AU2412000 A AU 2412000A AU 769471 B2 AU769471 B2 AU 769471B2
Authority
AU
Australia
Prior art keywords
cells
epithelial tissue
body according
detect abnormal
abnormal cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU24120/00A
Other languages
English (en)
Other versions
AU2412000A (en
Inventor
Drore Eisen
Stephen Frist
Joel Recht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CDX LABORATORIES Inc
Original Assignee
CDX LAB Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/298,219 external-priority patent/US6297044B1/en
Priority claimed from US09/298,218 external-priority patent/US6284482B1/en
Application filed by CDX LAB Inc filed Critical CDX LAB Inc
Publication of AU2412000A publication Critical patent/AU2412000A/en
Application granted granted Critical
Publication of AU769471B2 publication Critical patent/AU769471B2/en
Assigned to CDX LABORATORIES, INC. reassignment CDX LABORATORIES, INC. Amend patent request/document other than specification (104) Assignors: ORALSCAN LABORATORIES, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B2010/0216—Sampling brushes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N2015/1472—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle with colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1488—Methods for deciding
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20084—Artificial neural networks [ANN]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Signal Processing (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Theoretical Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Sewage (AREA)
  • Testing Or Measuring Of Semiconductors Or The Like (AREA)
AU24120/00A 1999-02-23 2000-01-12 Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium Ceased AU769471B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12125599P 1999-02-23 1999-02-23
US60/121255 1999-02-23
US09/298218 1999-04-23
US09/298219 1999-04-23
US09/298,219 US6297044B1 (en) 1999-02-23 1999-04-23 Minimally invasive apparatus for testing lesions of the oral cavity and similar epithelium
US09/298,218 US6284482B1 (en) 1999-04-23 1999-04-23 Method for detection of abnormal keratinization in epithelial tissue
PCT/US2000/000743 WO2000051066A1 (en) 1999-02-23 2000-01-12 Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2004201764A Division AU2004201764B2 (en) 1999-02-23 2004-04-27 Minimally Invasive Apparatus and Method for Testing Lesions of the Oral Cavity and Similar Epithelium

Publications (2)

Publication Number Publication Date
AU2412000A AU2412000A (en) 2000-09-14
AU769471B2 true AU769471B2 (en) 2004-01-29

Family

ID=27382597

Family Applications (2)

Application Number Title Priority Date Filing Date
AU24120/00A Ceased AU769471B2 (en) 1999-02-23 2000-01-12 Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium
AU2004201764A Ceased AU2004201764B2 (en) 1999-02-23 2004-04-27 Minimally Invasive Apparatus and Method for Testing Lesions of the Oral Cavity and Similar Epithelium

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2004201764A Ceased AU2004201764B2 (en) 1999-02-23 2004-04-27 Minimally Invasive Apparatus and Method for Testing Lesions of the Oral Cavity and Similar Epithelium

Country Status (12)

Country Link
US (1) US20020012938A1 (enExample)
EP (1) EP1155381B1 (enExample)
JP (1) JP4748628B2 (enExample)
CN (1) CN100339862C (enExample)
AT (1) ATE472775T1 (enExample)
AU (2) AU769471B2 (enExample)
CA (1) CA2363833C (enExample)
DE (1) DE60044604D1 (enExample)
DK (1) DK1155381T3 (enExample)
IL (2) IL144933A0 (enExample)
PT (1) PT1155381E (enExample)
WO (1) WO2000051066A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005064338A1 (en) * 2003-12-23 2005-07-14 University Of Florida Research Foundation, Inc. Microparticles for use in diagnostic methods
US8099600B2 (en) * 2004-08-23 2012-01-17 International Business Machines Corporation Content distribution site spoofing detection and prevention
NZ620811A (en) 2005-05-09 2015-09-25 Theranos Inc Point-of-care fluidic systems and uses thereof
JP2007114076A (ja) * 2005-10-21 2007-05-10 Pola Chem Ind Inc 角層細胞の画像の調整方法
MY165876A (en) 2009-10-19 2018-05-18 Theranos Inc Integrated health data capture and analysis system
KR20180078243A (ko) * 2015-11-05 2018-07-09 가부시키가이샤 시세이도 각질층 채취구 및 각질층 채취 검출용 키트
CN106570505B (zh) * 2016-11-01 2020-08-21 北京昆仑医云科技有限公司 对组织病理图像进行分析的方法和系统
US12235272B2 (en) 2020-01-13 2025-02-25 New York University Screening and assessment of potentially malignant oral lesions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5257182A (en) * 1991-01-29 1993-10-26 Neuromedical Systems, Inc. Morphological classification system and method
US5740270A (en) * 1988-04-08 1998-04-14 Neuromedical Systems, Inc. Automated cytological specimen classification system and method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2847990A (en) * 1956-03-20 1958-08-19 Ayre James Ernest Instrument for obtaining cells for cytodiagnosis
JPS5615731A (en) * 1979-07-20 1981-02-16 Olympus Optical Co Manufacture of cell diagnosing brush
US5623941A (en) * 1988-05-10 1997-04-29 Nils Stormby Cervical sampling velour brush
CA1340245C (en) * 1989-04-21 1998-12-15 John Samuel Monoclonal antibody for differentiation of squamous cell carcinoma antigens and method of use for same
US5184626A (en) * 1991-05-21 1993-02-09 Hicken William J Brush overlay Pap smear
CA2137282A1 (en) * 1992-08-07 1994-02-17 Katherine W. Klinger Process for obtaining a non-liquid cell sample
US5733721A (en) * 1992-11-20 1998-03-31 The Board Of Regents Of The University Of Oklahoma Cell analysis method using quantitative fluorescence image analysis
AU3585495A (en) * 1994-09-20 1996-04-09 Neopath, Inc. Biological analysis system self-calibration apparatus
US5713369A (en) * 1995-09-13 1998-02-03 Vance Products Inc. Uterine endometrial tissue sample brush
CA2355661C (en) * 1998-07-23 2006-04-11 The Oralscan/Trylon Joint Venture Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5740270A (en) * 1988-04-08 1998-04-14 Neuromedical Systems, Inc. Automated cytological specimen classification system and method
US5257182A (en) * 1991-01-29 1993-10-26 Neuromedical Systems, Inc. Morphological classification system and method
US5257182B1 (en) * 1991-01-29 1996-05-07 Neuromedical Systems Inc Morphological classification system and method

Also Published As

Publication number Publication date
WO2000051066A1 (en) 2000-08-31
PT1155381E (pt) 2010-10-11
ATE472775T1 (de) 2010-07-15
EP1155381B1 (en) 2010-06-30
AU2004201764B8 (en) 2004-05-27
CA2363833A1 (en) 2000-08-31
US20020012938A1 (en) 2002-01-31
JP2002538441A (ja) 2002-11-12
AU2412000A (en) 2000-09-14
EP1155381A4 (en) 2006-01-04
AU2004201764A1 (en) 2004-05-27
DE60044604D1 (de) 2010-08-12
JP4748628B2 (ja) 2011-08-17
CN100339862C (zh) 2007-09-26
EP1155381A1 (en) 2001-11-21
CN1341244A (zh) 2002-03-20
AU2004201764B2 (en) 2007-11-22
CA2363833C (en) 2007-04-03
IL144933A0 (en) 2002-06-30
IL144933A (en) 2006-07-05
DK1155381T3 (da) 2010-11-01

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Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: CDX LABORATORIES, INC.

Free format text: FORMER NAME: ORALSCAN LABORATORIES, INC.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired