AU761206B2 - Methods of downmodulating the immune response to therapeutic proteins - Google Patents

Methods of downmodulating the immune response to therapeutic proteins Download PDF

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Publication number
AU761206B2
AU761206B2 AU60578/99A AU6057899A AU761206B2 AU 761206 B2 AU761206 B2 AU 761206B2 AU 60578/99 A AU60578/99 A AU 60578/99A AU 6057899 A AU6057899 A AU 6057899A AU 761206 B2 AU761206 B2 AU 761206B2
Authority
AU
Australia
Prior art keywords
agent
antibody
factor viii
cell
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU60578/99A
Other languages
English (en)
Other versions
AU6057899A (en
Inventor
Mary Collins
Gary S. Gray
Leon W. Hoyer
Jiahua Qian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Genetics Institute LLC
Original Assignee
American National Red Cross
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross, Genetics Institute LLC filed Critical American National Red Cross
Publication of AU6057899A publication Critical patent/AU6057899A/en
Assigned to GENETICS INSTITUTE, LLC, AMERICAN RED CROSS reassignment GENETICS INSTITUTE, LLC Change of Name of Applicant under S 104 Assignors: AMERICAN RED CROSS, GENETICS INSTITUTE INC.
Application granted granted Critical
Publication of AU761206B2 publication Critical patent/AU761206B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU60578/99A 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins Ceased AU761206B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15817898A 1998-09-21 1998-09-21
US09/158178 1998-09-21
PCT/US1999/021991 WO2000016801A1 (en) 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins

Publications (2)

Publication Number Publication Date
AU6057899A AU6057899A (en) 2000-04-10
AU761206B2 true AU761206B2 (en) 2003-05-29

Family

ID=22566971

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60578/99A Ceased AU761206B2 (en) 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins

Country Status (21)

Country Link
EP (1) EP1115423A1 (hu)
JP (1) JP2002526455A (hu)
KR (1) KR20010085830A (hu)
CN (1) CN1331602A (hu)
AU (1) AU761206B2 (hu)
BR (1) BR9913991A (hu)
CA (1) CA2343916A1 (hu)
CZ (1) CZ20011021A3 (hu)
EA (1) EA005236B1 (hu)
HK (1) HK1039059A1 (hu)
HU (1) HUP0103960A3 (hu)
IL (1) IL142069A0 (hu)
LT (1) LT4920B (hu)
LV (1) LV12768B (hu)
MX (1) MXPA01002898A (hu)
NO (1) NO20011412L (hu)
NZ (1) NZ511034A (hu)
PL (1) PL346796A1 (hu)
SI (1) SI20626A (hu)
WO (1) WO2000016801A1 (hu)
ZA (1) ZA200103156B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397703A (en) 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
WO2001089564A2 (en) * 2000-05-19 2001-11-29 The Center For Blood Research, Inc. Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity
JP2007516509A (ja) * 2003-06-10 2007-06-21 スミスズ ディテクション インコーポレイティド センサ装置
GB201508024D0 (en) 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996012406A1 (en) * 1994-10-19 1996-05-02 Genetic Therapy, Inc. Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents
AU8153698A (en) * 1997-06-20 1999-01-04 Biogen Idec Ma Inc. Cd154 blockade therapy for therapeutic protein inhibitor syndrome

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171569A (en) 1985-03-15 1992-12-15 National Research Development Corporation Factor IX preparations uncontaminated by plasma components or pox virus
JPH0788399B2 (ja) 1985-04-12 1995-09-27 ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド 新規プロコアギュラント蛋白質
US5422260A (en) 1986-05-29 1995-06-06 Genetics Institute, Inc. -Legal Affairs Human factor VIII:c muteins
US4994371A (en) 1987-08-28 1991-02-19 Davie Earl W DNA preparation of Christmas factor and use of DNA sequences
FR2657884B1 (fr) 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
US5770197A (en) 1991-06-27 1998-06-23 Bristol-Myers Squibb Company Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
JP3722375B2 (ja) 1991-06-27 2005-11-30 ブリストル−マイヤーズ スクイブ カンパニー Ｃｔｌａ４レセプター、それを含有する融合タンパク質およびそれらの使用
WO1993009804A1 (en) 1991-11-18 1993-05-27 The Scripps Research Institute Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation
US5744446A (en) 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
US5364771A (en) 1992-04-07 1994-11-15 Emory University Hybrid human/porcine factor VIII
US5663060A (en) 1992-04-07 1997-09-02 Emory University Hybrid human/animal factor VIII
US5621039A (en) 1993-06-08 1997-04-15 Hallahan; Terrence W. Factor IX- polymeric conjugates
EP0776217A1 (en) * 1994-08-19 1997-06-04 Novo Nordisk A/S A method of treating a patient with a biologically active compound
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
US5916560A (en) * 1996-03-20 1999-06-29 Bristol-Myers Squibb Company Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4/CD28/B7 pathways and compositions for use therewith
BR9807471A (pt) * 1997-01-10 2000-03-21 Biogen Inc Uso do composto anti-cd40l
US8151477B2 (en) 2009-11-06 2012-04-10 Hexagon Metrology Ab CMM with modular functionality

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996012406A1 (en) * 1994-10-19 1996-05-02 Genetic Therapy, Inc. Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents
AU8153698A (en) * 1997-06-20 1999-01-04 Biogen Idec Ma Inc. Cd154 blockade therapy for therapeutic protein inhibitor syndrome

Also Published As

Publication number Publication date
WO2000016801A1 (en) 2000-03-30
EP1115423A1 (en) 2001-07-18
CN1331602A (zh) 2002-01-16
HUP0103960A3 (en) 2003-09-29
LV12768A (en) 2001-12-20
EA200100385A1 (ru) 2001-10-22
NZ511034A (en) 2004-03-26
LT4920B (lt) 2002-06-25
HK1039059A1 (zh) 2002-04-12
WO2000016801A9 (en) 2000-10-26
BR9913991A (pt) 2001-07-03
LT2001045A (en) 2002-01-25
JP2002526455A (ja) 2002-08-20
PL346796A1 (en) 2002-02-25
ZA200103156B (en) 2002-07-18
KR20010085830A (ko) 2001-09-07
NO20011412D0 (no) 2001-03-20
SI20626A (sl) 2002-02-28
HUP0103960A2 (hu) 2002-02-28
MXPA01002898A (es) 2002-06-04
IL142069A0 (en) 2002-03-10
AU6057899A (en) 2000-04-10
LV12768B (lv) 2002-06-20
CZ20011021A3 (cs) 2001-10-17
CA2343916A1 (en) 2000-03-30
NO20011412L (no) 2001-05-16
EA005236B1 (ru) 2004-12-30

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Legal Events

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TC Change of applicant's name (sec. 104)

Owner name: GENETICS INSTITUTE, LLC, AMERICAN RED CROSS

Free format text: FORMER NAME: GENETICS INSTITUTE, INC., AMERICAN RED CROSS

FGA Letters patent sealed or granted (standard patent)