AU751581C - Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor - Google Patents
Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursorInfo
- Publication number
- AU751581C AU751581C AU74811/98A AU7481198A AU751581C AU 751581 C AU751581 C AU 751581C AU 74811/98 A AU74811/98 A AU 74811/98A AU 7481198 A AU7481198 A AU 7481198A AU 751581 C AU751581 C AU 751581C
- Authority
- AU
- Australia
- Prior art keywords
- cells
- nep
- cns
- population
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0661—Smooth muscle cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/113—Acidic fibroblast growth factor (aFGF, FGF-1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/08—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Developmental Biology & Embryology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2002309073A AU2002309073B2 (en) | 1997-05-07 | 2002-11-22 | Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/852744 | 1997-05-07 | ||
| US08/852,744 US6361996B1 (en) | 1997-05-07 | 1997-05-07 | Neuroepithelial stem cells and glial-restricted intermediate precursors |
| US09/073,881 US6830927B2 (en) | 1997-05-07 | 1998-05-06 | Common neural progenitor for the CNS and PNS |
| US09/073881 | 1998-05-06 | ||
| PCT/US1998/009630 WO1998050526A1 (en) | 1997-05-07 | 1998-05-07 | Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor |
| US10/025,333 US7037720B2 (en) | 1997-05-07 | 2001-12-19 | Neuroepithelial stem cells and glial-restricted intermediate precursors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002309073A Division AU2002309073B2 (en) | 1997-05-07 | 2002-11-22 | Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU7481198A AU7481198A (en) | 1998-11-27 |
| AU751581B2 AU751581B2 (en) | 2002-08-22 |
| AU751581C true AU751581C (en) | 2003-06-19 |
Family
ID=37057261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU74811/98A Ceased AU751581C (en) | 1997-05-07 | 1998-05-07 | Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US6361996B1 (OSRAM) |
| EP (1) | EP0983344A4 (OSRAM) |
| JP (1) | JP2002513291A (OSRAM) |
| AU (1) | AU751581C (OSRAM) |
| CA (1) | CA2289021C (OSRAM) |
| IL (1) | IL132584A0 (OSRAM) |
| WO (1) | WO1998050526A1 (OSRAM) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8263402B1 (en) * | 1998-10-19 | 2012-09-11 | Cornell Research Foundation, Inc. | Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US7410798B2 (en) | 2001-01-10 | 2008-08-12 | Geron Corporation | Culture system for rapid expansion of human embryonic stem cells |
| US20050042749A1 (en) | 2001-05-16 | 2005-02-24 | Carpenter Melissa K. | Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease |
| IL152741A0 (en) | 2000-05-17 | 2003-06-24 | Geron Corp | Neural progenitor cell populations |
| US7250294B2 (en) | 2000-05-17 | 2007-07-31 | Geron Corporation | Screening small molecule drugs using neural cells differentiated from human embryonic stem cells |
| US6897061B1 (en) * | 2000-06-16 | 2005-05-24 | Spinal Cord Society | Transdifferentiation of glial cells |
| WO2003070171A2 (en) | 2002-02-15 | 2003-08-28 | Cornell Research Foundation, Inc. | Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells |
| US7207743B2 (en) * | 2002-05-28 | 2007-04-24 | Polivka Parking Solutions Llc | Method and apparatus for constructing an automotive vehicle parking lot |
| US7285415B2 (en) | 2002-07-11 | 2007-10-23 | The Regents Of The University Of California | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| US20050101014A1 (en) | 2002-07-11 | 2005-05-12 | Keirstead Hans S. | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| AR046076A1 (es) * | 2003-07-18 | 2005-11-23 | Otsuka Pharma Co Ltd | Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida |
| EP1682075A4 (en) * | 2003-11-07 | 2009-12-09 | Univ Florida | BREEDING AND DIFFERENTIATION OF NEURAL CREATOR CELLS |
| ES2491891T3 (es) | 2004-01-16 | 2014-09-08 | Carnegie Mellon University | Marcaje celular para técnicas de resonancia magnética nuclear |
| GB2414995B (en) | 2004-06-09 | 2006-11-15 | Univ Edinburgh | Neural stem cells |
| JP2008526916A (ja) * | 2005-01-19 | 2008-07-24 | フィディア アドバンスド バイオポリマーズ ソシエタ ア レスポンサビリタ リミタータ | Sciおよびpnt再生のためのヒアルロン酸誘導体および神経幹細胞 |
| US7803364B2 (en) | 2005-11-17 | 2010-09-28 | The Cleveland Clinic Foundation | Multipotent neural stem cells |
| WO2008054509A2 (en) * | 2006-04-14 | 2008-05-08 | Celsense, Inc. | Methods for assessing cell labeling |
| CA2649333C (en) * | 2006-04-14 | 2016-10-04 | Carnegie Mellon University | Cellular labeling and quantification for nuclear magnetic resonance techniques |
| JP2010500047A (ja) | 2006-08-15 | 2010-01-07 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 間葉系幹細胞馴化培地 |
| US8163075B2 (en) | 2006-10-31 | 2012-04-24 | Sensient Colors Llc | Inks comprising modified pigments and methods for making and using the same |
| AU2008242987A1 (en) * | 2007-04-17 | 2008-10-30 | University Of Rochester | Telencephalic glial-restricted cell populations and related compositions and methods |
| AU2008275578B2 (en) * | 2007-07-10 | 2014-04-10 | Carnegie Mellon University | Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques |
| EP3483222A3 (en) | 2007-08-23 | 2019-08-07 | Sensient Colors LLC | Self-dispersed pigments and methods for making and using the same |
| US8513009B2 (en) | 2008-01-30 | 2013-08-20 | Geron Corporation | Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells |
| SG188918A1 (OSRAM) | 2008-03-17 | 2013-04-30 | Agency Science Tech & Res | |
| AU2009241762B2 (en) * | 2008-05-02 | 2015-07-16 | Celsense Inc. | Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications |
| US9709553B2 (en) | 2008-05-08 | 2017-07-18 | University Of Rochester | Treating myelin diseases with optimized cell preparations |
| US9688956B2 (en) | 2008-06-05 | 2017-06-27 | National Cheng Kung University | Method for preserving proliferation and differentiation potential of mesenchymal stem cells |
| WO2010008486A2 (en) | 2008-06-24 | 2010-01-21 | Parkinsons Institute | Pluripotent cell lines and methods of use thereof |
| WO2010068946A1 (en) * | 2008-12-12 | 2010-06-17 | Nova Southeastern University | Methods of isolating and using stem cells |
| CN102325878A (zh) | 2008-12-23 | 2012-01-18 | 斯特姆塞尔思加利福尼亚有限公司 | 少突胶质前体细胞的靶向细胞群及制备与使用方法 |
| JP2012523479A (ja) | 2009-04-07 | 2012-10-04 | センシエント カラーズ エルエルシー | 自己分散性粒子並びにその製造方法及び使用方法 |
| EP2456853B1 (en) | 2009-07-21 | 2020-10-28 | ABT Holding Company | Use of stem cells to reduce leukocyte extravasation |
| US20110020292A1 (en) | 2009-07-21 | 2011-01-27 | Abt Holding Company | Use of Stem Cells to Reduce Leukocyte Extravasation |
| NZ602174A (en) * | 2010-02-05 | 2014-10-31 | Auckland Uniservices Ltd | Cell programming |
| SG183497A1 (en) | 2010-02-25 | 2012-09-27 | Abt Holding Co | Modulation of macrophage activation |
| US8895291B2 (en) | 2010-10-08 | 2014-11-25 | Terumo Bct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
| US8433419B2 (en) | 2010-10-13 | 2013-04-30 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling neurostimulation according to physical state |
| WO2012168295A1 (en) | 2011-06-06 | 2012-12-13 | ReGenesys BVBA | Expansion of stem cells in hollow fiber bioreactors |
| WO2014124087A1 (en) | 2013-02-06 | 2014-08-14 | University Of Rochester | Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders |
| US9896656B2 (en) | 2013-03-15 | 2018-02-20 | Wake Forest University Health Sciences | Neural progenitor cell differentiation |
| PT2983680T (pt) | 2013-04-12 | 2020-10-29 | Abt Holding Co | Melhoria de órgãos para transplante |
| ES2753323T3 (es) | 2013-04-30 | 2020-04-08 | Univ Leuven Kath | Terapia celular para síndromes mielodisplásicos |
| JP6612227B2 (ja) | 2013-11-16 | 2019-11-27 | テルモ ビーシーティー、インコーポレーテッド | バイオリアクターにおける細胞増殖 |
| US9724432B2 (en) | 2015-04-30 | 2017-08-08 | University Of Rochester | Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder |
| WO2017147212A1 (en) | 2016-02-22 | 2017-08-31 | The Regents Of The University Of California | Compositions and methods for imaging cell populations |
| CN109219657A (zh) | 2016-03-30 | 2019-01-15 | 阿斯特利亚斯生物治疗股份公司 | 少突胶质细胞祖细胞组合物 |
| EP4549457A3 (en) * | 2017-01-31 | 2025-05-28 | Osaka University | Differentiation control method for pluripotent stem cells |
| JP7457505B2 (ja) | 2017-05-10 | 2024-03-28 | ユニバーシティー オブ ロチェスター | 神経精神障害を処置する方法 |
| IL281628B2 (en) | 2018-09-19 | 2025-06-01 | Lineage Cell Therapeutics Inc | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| US11603518B2 (en) * | 2019-01-23 | 2023-03-14 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
| JP7728747B2 (ja) | 2019-08-23 | 2025-08-25 | サナ バイオテクノロジー,インコーポレイテッド | Cd24発現細胞およびそれらの用途 |
| BR112022019060A2 (pt) | 2020-03-25 | 2022-11-29 | Sana Biotechnology Inc | Células neurais hipoimunogênicas para o tratamento de distúrbios e condições neurológicas |
| IL300516A (en) | 2020-08-13 | 2023-04-01 | Sana Biotechnology Inc | Methods for treating susceptible patients with hypoimmunogenic cells, and related methods and compounds |
| BR112023024434A2 (pt) | 2021-05-27 | 2024-02-20 | Sana Biotechnology Inc | Células hipoimunogênicas que compreendem hla-e ou hla-g geneticamente modificadas |
| EP4370544A2 (en) | 2021-07-14 | 2024-05-22 | Sana Biotechnology, Inc. | Altered expression of y chromosome-linked antigens in hypoimmunogenic cells |
| AU2022325955A1 (en) | 2021-08-11 | 2024-02-08 | Sana Biotechnology, Inc. | Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions |
| WO2023019226A1 (en) | 2021-08-11 | 2023-02-16 | Sana Biotechnology, Inc. | Genetically modified cells for allogeneic cell therapy |
| MX2024001443A (es) | 2021-08-11 | 2024-05-15 | Sana Biotechnology Inc | Sistemas inducibles para alterar la expresión génica en células hipoinmunógenas. |
| JP2024534771A (ja) | 2021-08-11 | 2024-09-26 | サナ バイオテクノロジー,インコーポレイテッド | 補体媒介性炎症反応を低減するための同種異系細胞療法のための遺伝子改変細胞 |
| WO2023183313A1 (en) | 2022-03-22 | 2023-09-28 | Sana Biotechnology, Inc. | Engineering cells with a transgene in b2m or ciita locus and associated compositions and methods |
| WO2025054202A1 (en) | 2023-09-05 | 2025-03-13 | Sana Biotechnology, Inc. | Method of screening a sample comprising a transgene with a unique barcode |
| WO2025151838A1 (en) | 2024-01-12 | 2025-07-17 | Sana Biotechnology, Inc. | Safety switches to control in vitro and in vivo proliferation of cell therapy products |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411883A (en) * | 1989-12-26 | 1995-05-02 | Somatix Therapy Corporation | Proliferated neuron progenitor cell product and process |
| WO1994002593A1 (en) * | 1992-07-27 | 1994-02-03 | California Institute Of Technology | Mammalian multipotent neural stem cells |
| US5589376A (en) | 1992-07-27 | 1996-12-31 | California Institute Of Technology | Mammalian neural crest stem cells |
| US5753506A (en) * | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
-
1997
- 1997-05-07 US US08/852,744 patent/US6361996B1/en not_active Expired - Lifetime
-
1998
- 1998-05-06 US US09/073,881 patent/US6830927B2/en not_active Expired - Fee Related
- 1998-05-07 WO PCT/US1998/009630 patent/WO1998050526A1/en not_active Ceased
- 1998-05-07 AU AU74811/98A patent/AU751581C/en not_active Ceased
- 1998-05-07 CA CA2289021A patent/CA2289021C/en not_active Expired - Fee Related
- 1998-05-07 IL IL13258498A patent/IL132584A0/xx not_active IP Right Cessation
- 1998-05-07 EP EP98922212A patent/EP0983344A4/en not_active Withdrawn
- 1998-05-07 JP JP54858198A patent/JP2002513291A/ja not_active Ceased
-
2001
- 2001-12-19 US US10/025,333 patent/US7037720B2/en not_active Expired - Fee Related
-
2006
- 2006-05-01 US US11/415,056 patent/US7595194B2/en not_active Expired - Fee Related
-
2009
- 2009-09-28 US US12/568,419 patent/US20100015702A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6361996B1 (en) | 2002-03-26 |
| US20060199264A1 (en) | 2006-09-07 |
| US20100015702A1 (en) | 2010-01-21 |
| WO1998050526A1 (en) | 1998-11-12 |
| CA2289021A1 (en) | 1998-11-12 |
| EP0983344A1 (en) | 2000-03-08 |
| AU7481198A (en) | 1998-11-27 |
| US7595194B2 (en) | 2009-09-29 |
| JP2002513291A (ja) | 2002-05-08 |
| AU751581B2 (en) | 2002-08-22 |
| EP0983344A4 (en) | 2000-09-27 |
| US20020142460A1 (en) | 2002-10-03 |
| US7037720B2 (en) | 2006-05-02 |
| IL132584A0 (en) | 2001-03-19 |
| CA2289021C (en) | 2013-07-09 |
| US6830927B2 (en) | 2004-12-14 |
| US20020045251A1 (en) | 2002-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DA2 | Applications for amendment section 104 |
Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20021127 |
|
| FGA | Letters patent sealed or granted (standard patent) | ||
| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS AS WAS NOTIFIED IN THE OFFICIAL JOURNAL DATED 20030102 |