AU737829B2 - Conjugates that contain the homeodomain of antennapedia - Google Patents
Conjugates that contain the homeodomain of antennapedia Download PDFInfo
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- AU737829B2 AU737829B2 AU88776/98A AU8877698A AU737829B2 AU 737829 B2 AU737829 B2 AU 737829B2 AU 88776/98 A AU88776/98 A AU 88776/98A AU 8877698 A AU8877698 A AU 8877698A AU 737829 B2 AU737829 B2 AU 737829B2
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- conjugate
- region
- protein
- conjugate according
- nucleic acid
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
- C07K14/43581—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies from Drosophila
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| GB9718609 | 1997-09-02 | ||
| GBGB9718609.2A GB9718609D0 (en) | 1997-09-02 | 1997-09-02 | Fusion protein |
| PCT/GB1998/002628 WO1999011809A1 (en) | 1997-09-02 | 1998-09-02 | Conjugates that contain the homeodomain of antennapedia |
Publications (2)
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| AU8877698A AU8877698A (en) | 1999-03-22 |
| AU737829B2 true AU737829B2 (en) | 2001-08-30 |
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| JP (1) | JP2001514858A (enExample) |
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| IL (2) | IL134602A0 (enExample) |
| NZ (1) | NZ503007A (enExample) |
| WO (1) | WO1999011809A1 (enExample) |
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| US6221355B1 (en) * | 1997-12-10 | 2001-04-24 | Washington University | Anti-pathogen system and methods of use thereof |
| GB9814527D0 (en) | 1998-07-03 | 1998-09-02 | Cyclacel Ltd | Delivery system |
| JP4854853B2 (ja) | 1998-11-12 | 2012-01-18 | ライフ テクノロジーズ コーポレーション | トランスフェクション薬剤 |
| JP2002530059A (ja) * | 1998-11-13 | 2002-09-17 | サイクラセル・リミテッド | 輸送ベクター |
| WO2000038733A1 (en) * | 1998-12-24 | 2000-07-06 | Ucb S.A. | Peptidic product, process and composition |
| US6773920B1 (en) | 1999-03-31 | 2004-08-10 | Invitrogen Corporation | Delivery of functional protein sequences by translocating polypeptides |
| AU775001B2 (en) * | 1999-03-31 | 2004-07-15 | Invitrogen Corporation | Delivery of functional protein sequences by translocating polypeptides |
| US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| IL150510A0 (en) * | 2000-01-07 | 2003-02-12 | Artemis Pharmaceuticals Gmbh | Transduction of recombinases for inducible gene targeting |
| EP1118668A1 (en) * | 2000-01-07 | 2001-07-25 | ARTEMIS Pharmaceuticals GmbH | Transduction of recombinases for inducible gene targeting |
| GB0003284D0 (en) * | 2000-02-15 | 2000-04-05 | Secr Defence Brit | Anti-viral therapy |
| RU2002130200A (ru) * | 2000-04-12 | 2004-03-27 | Импликс Лтд. (Gb) | Композиции для доставки лекарственного средства |
| DE10027777A1 (de) * | 2000-06-07 | 2001-12-13 | Otogene Ag | Transfektionsverfahren |
| GB0015090D0 (en) * | 2000-06-20 | 2000-08-09 | Implyx Ltd | Gene-activating conjugates |
| KR100374050B1 (ko) * | 2000-07-26 | 2003-03-03 | 최수영 | 세포침투성 융합단백질, 이를 코딩하는 재조합폴리뉴클레오타이드 및 발현벡터 |
| AU2001288955A1 (en) * | 2000-09-07 | 2002-03-22 | Vanderbilt University | Genome engineering by cell-permeable dna site-specific recombinases |
| US6472176B2 (en) * | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| CA2367636C (en) | 2001-04-12 | 2010-05-04 | Lisa Mckerracher | Fusion proteins |
| US7442686B2 (en) | 2001-04-12 | 2008-10-28 | Bioaxone Therapeutique Inc. | Treatment of macular degeneration with ADP-ribosyl transferase fusion protein therapeutic compositions |
| CA2452865A1 (en) * | 2001-06-07 | 2002-12-12 | Skinmedica, Inc. | Conditioned cell culture media and uses thereof |
| US20050136040A1 (en) * | 2001-10-11 | 2005-06-23 | Imperial College Innovations Limited | Control of gene expression using a complex of an oligonucleotide and a regulatory peptide |
| GB0124391D0 (en) * | 2001-10-11 | 2001-11-28 | Gene Expression Technologies L | Control of gene expression |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| DE102007041655A1 (de) | 2007-09-03 | 2009-03-05 | Medicyte Gmbh | Vermehrung von primären Zellen und deren Verwendung |
| US8119366B2 (en) * | 2007-10-05 | 2012-02-21 | Trojan Technologies, Ltd. | Antennapedia-dominant negative mastermind-like construct |
| CA2758378A1 (en) | 2009-04-14 | 2010-10-21 | Trojan Technologies Ltd. | Therapeutic antennapedia-antibody molecules and methods of use thereof |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| DE102010041958A1 (de) | 2010-10-04 | 2012-04-05 | Medicyte Gmbh | Geeignete Hepatozyten für in-vitro Genotoxitätstests |
| WO2012154684A2 (en) * | 2011-05-06 | 2012-11-15 | University Of Rochester | Method of preventing development of psoriatic lesions |
| ES2633343T3 (es) | 2011-06-13 | 2017-09-20 | The Board Of Trustees Of The University Of Illionis | Composiciones de péptidos y métodos para tratar lesión pulmonar, asma, anafilaxis, angioedema, síndromes de permeabilidad vascular sistémica y congestión nasal |
| AU2013246034B2 (en) | 2012-04-09 | 2017-12-07 | Case Western Reserve University | Compositions and methods for inhibiting the activity of LAR family phosphatases |
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| DK3581207T5 (da) | 2013-06-11 | 2024-09-02 | Ppl Bvi Ltd | Fusionsproteiner omfattende hoxd12 og nemo-bindingsdomæne og anvendelse deraf |
| EP2927685A1 (en) | 2014-04-02 | 2015-10-07 | Medicyte GmbH | Suitable hepatocytes for in-vitro hepatitis tests |
| CN106572974B (zh) | 2014-07-15 | 2021-04-23 | 生命技术公司 | 用于将分子有效递送到细胞的具有脂质聚集体的组合物和方法 |
| CA2962444C (en) | 2014-10-03 | 2023-09-05 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
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| FR2739621B1 (fr) * | 1995-10-05 | 1997-12-05 | Centre Nat Rech Scient | Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives |
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1998
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- 1998-09-02 JP JP2000508817A patent/JP2001514858A/ja active Pending
- 1998-09-02 CA CA002301157A patent/CA2301157A1/en not_active Abandoned
- 1998-09-02 EP EP98940453A patent/EP1009847A1/en not_active Withdrawn
- 1998-09-02 IL IL13460298A patent/IL134602A0/xx active IP Right Grant
- 1998-09-02 NZ NZ503007A patent/NZ503007A/xx not_active IP Right Cessation
- 1998-09-02 WO PCT/GB1998/002628 patent/WO1999011809A1/en not_active Ceased
- 1998-09-02 BR BR9811744-0A patent/BR9811744A/pt not_active Application Discontinuation
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2000
- 2000-02-17 IL IL134602A patent/IL134602A/en not_active IP Right Cessation
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2004
- 2004-02-27 US US10/789,403 patent/US7968512B2/en not_active Expired - Lifetime
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2011
- 2011-06-24 US US13/168,167 patent/US8735340B2/en not_active Expired - Fee Related
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| BONFANTI ET AL. CANCER RES.1997 * |
| PROCHIANTZ. CURRENT OP. NEUROBIOL.1996 * |
| SCHULZE-REDELMEIER. J IMMUNOL.1996 * |
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| IL134602A0 (en) | 2001-04-30 |
| US20080317773A1 (en) | 2008-12-25 |
| NZ503007A (en) | 2000-11-24 |
| BR9811744A (pt) | 2002-01-02 |
| US20110256168A1 (en) | 2011-10-20 |
| CA2301157A1 (en) | 1999-03-11 |
| AU8877698A (en) | 1999-03-22 |
| WO1999011809A1 (en) | 1999-03-11 |
| EP1009847A1 (en) | 2000-06-21 |
| JP2001514858A (ja) | 2001-09-18 |
| IL134602A (en) | 2006-10-31 |
| US7968512B2 (en) | 2011-06-28 |
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