AU732426B2 - A method of analysing a sample of free cells - Google Patents
A method of analysing a sample of free cells Download PDFInfo
- Publication number
- AU732426B2 AU732426B2 AU18817/00A AU1881700A AU732426B2 AU 732426 B2 AU732426 B2 AU 732426B2 AU 18817/00 A AU18817/00 A AU 18817/00A AU 1881700 A AU1881700 A AU 1881700A AU 732426 B2 AU732426 B2 AU 732426B2
- Authority
- AU
- Australia
- Prior art keywords
- suspension
- sample
- platelets
- cell
- stress
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 239000012634 fragment Substances 0.000 claims description 40
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- 230000003204 osmotic effect Effects 0.000 claims description 6
- 238000000338 in vitro Methods 0.000 claims description 4
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- 239000006285 cell suspension Substances 0.000 claims description 3
- 238000001514 detection method Methods 0.000 claims description 3
- 239000000470 constituent Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 75
- 230000035882 stress Effects 0.000 description 29
- 206010001497 Agitation Diseases 0.000 description 19
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- 210000000601 blood cell Anatomy 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 230000009089 cytolysis Effects 0.000 description 5
- 210000003743 erythrocyte Anatomy 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
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- 208000024320 Abnormal platelet count Diseases 0.000 description 1
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- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical group [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
- G01N13/04—Investigating osmotic effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1029—Particle size
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9828765.9A GB9828765D0 (en) | 1998-12-29 | 1998-12-29 | A method of testing a cell sample |
| GB9828765 | 1998-12-29 | ||
| GB9910266 | 1999-05-04 | ||
| GBGB9910266.7A GB9910266D0 (en) | 1999-05-04 | 1999-05-04 | A method of analysing a sample of free cells |
| GB9910267 | 1999-05-04 | ||
| GBGB9910267.5A GB9910267D0 (en) | 1999-05-04 | 1999-05-04 | A method of determining the number of platelets in a cell suspension containing platelets |
| PCT/GB1999/004428 WO2000039559A2 (en) | 1998-12-29 | 1999-12-24 | A method of analysing a sample of free cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1881700A AU1881700A (en) | 2000-07-31 |
| AU732426B2 true AU732426B2 (en) | 2001-04-26 |
Family
ID=27269605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU18817/00A Expired AU732426B2 (en) | 1998-12-29 | 1999-12-24 | A method of analysing a sample of free cells |
Country Status (6)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2322910B1 (en) * | 1998-12-29 | 2019-03-13 | Ian Basil Shine | A method of analysing a sample of free cells |
| WO2006055615A2 (en) | 2004-11-15 | 2006-05-26 | University Of North Dakota | A method for single oxygen atom incorporation into digested peptides using peptidases |
| US7822276B2 (en) * | 2005-02-17 | 2010-10-26 | Iris International, Inc. | Method and apparatus for analyzing body fluids |
| JP5058320B2 (ja) * | 2010-09-16 | 2012-10-24 | シスメックス株式会社 | 血液撮像装置および血液撮像方法 |
| CN111033256B (zh) | 2017-09-05 | 2022-07-12 | 深圳迈瑞生物医疗电子股份有限公司 | 血小板聚集样本的报警方法、血细胞分析仪及存储介质 |
| CN111656161B (zh) | 2018-04-28 | 2024-02-20 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析仪异常的报警方法、系统及存储介质 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0010526A1 (en) * | 1978-09-07 | 1980-04-30 | SALUS ISTITUTO DIAGNOSTICO DI CROCE' DR.FRANCESCO & C. s.a.s. | Method and apparatus for investigating haemocoagulation or aggregation of platelets |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3502412A (en) * | 1967-10-16 | 1970-03-24 | Abbott Lab | Method and apparatus for measuring osmotic fragility of red blood cells by constantly reducing the concentration of the saline solution suspending the cells |
| US3606539A (en) * | 1968-11-13 | 1971-09-20 | American Optical Corp | Apparatus and method for measuring osmotic fragility of red blood cells |
| CA988319A (en) | 1973-10-11 | 1976-05-04 | Tomas Hirschfeld | System for differentiating particles |
| US3851246A (en) | 1973-11-26 | 1974-11-26 | Us Navy | Method of predicting the post transfusion viability of preserved erythrocytes and other similar cells |
| GB1481480A (en) * | 1974-02-02 | 1977-07-27 | Kernforschungsanlage Juelich | Process and apparatus for increasing the permeability of the membrane of cells of organisms |
| US4271001A (en) * | 1978-03-23 | 1981-06-02 | Asahi Kasei Kogyo Kabushiki Kaisha | Apparatus for measuring membrane characteristics of vesicles |
| US4240027A (en) * | 1978-08-31 | 1980-12-16 | The United States Of America As Represented By The Secretary Of The Army | Electromagnetic method for the noninvasive analysis of cell membrane physiology and pharmacology |
| US4375615A (en) * | 1979-04-20 | 1983-03-01 | Becton Dickinson And Company | Apparatus for counting particles in a liquid suspension |
| US4298836A (en) | 1979-11-23 | 1981-11-03 | Coulter Electronics, Inc. | Particle shape determination |
| US4374644A (en) * | 1981-04-06 | 1983-02-22 | Coulter Electronics, Inc. | Blood cell volume monitoring |
| US4535284A (en) * | 1981-07-10 | 1985-08-13 | Coulter Electronics, Inc. | High and low frequency analysis of osmotic stress of cells |
| DE3215719C2 (de) | 1982-04-28 | 1984-01-26 | Holger Dr. 5100 Aachen Kiesewetter | Meßeinrichtung zur Messung des Verformungsvermögens von roten Blutkörperchen |
| GB8408529D0 (en) | 1984-04-03 | 1984-05-16 | Health Lab Service Board | Concentration of biological particles |
| US4664796A (en) * | 1985-09-16 | 1987-05-12 | Coulter Electronics, Inc. | Flux diverting flow chamber for high gradient magnetic separation of particles from a liquid medium |
| US4791355A (en) | 1986-10-21 | 1988-12-13 | Coulter Electronics Inc. | Particle analyzer for measuring the resistance and reactance of a particle |
| US5223398A (en) | 1987-03-13 | 1993-06-29 | Coulter Corporation | Method for screening cells or formed bodies for enumeration of populations expressing selected characteristics |
| US5006460A (en) | 1988-05-26 | 1991-04-09 | Pantox Corporation | Method for measuring DNA damage in single cells |
| JP2966904B2 (ja) * | 1990-08-08 | 1999-10-25 | 株式会社日立製作所 | 細胞の処理方法、および処理装置 |
| US5548661A (en) | 1991-07-12 | 1996-08-20 | Price; Jeffrey H. | Operator independent image cytometer |
| JP2565844B2 (ja) * | 1992-02-07 | 1996-12-18 | アボツト・ラボラトリーズ | 細胞溶解処理条件下で異種細胞集団を正確に計数し，感受性に関する格付けを行う方法 |
| US5532139A (en) | 1992-10-30 | 1996-07-02 | Micro-Med, Inc. | Micro lysis-analysis process to measure cell characteristics and diagnose diseases |
| US5595866A (en) | 1994-05-27 | 1997-01-21 | Methodist Hospital Of Indiana, Inc. | Step-wise method to remove cryoprotectant from sperm |
| GB9526676D0 (en) * | 1995-12-29 | 1996-02-28 | Shine Thomas A | Method for testing a cell suspension |
| GB9526653D0 (en) | 1995-12-29 | 1996-02-28 | Shine Thomas A | Fluid delivery device |
| GB9526652D0 (en) | 1995-12-29 | 1996-02-28 | Shine Thomas A | Electrode assembly |
| GB9526684D0 (en) | 1995-12-29 | 1996-02-28 | Shine Thomas A | Method for testing a cell sample |
| EP1180678B1 (en) | 1995-12-29 | 2005-11-02 | Ian Basil Shine | Method for testing a cell sample |
| EP2322910B1 (en) * | 1998-12-29 | 2019-03-13 | Ian Basil Shine | A method of analysing a sample of free cells |
-
1999
- 1999-12-24 EP EP10183397.8A patent/EP2322910B1/en not_active Expired - Lifetime
- 1999-12-24 JP JP2000591409A patent/JP4402301B2/ja not_active Expired - Lifetime
- 1999-12-24 AU AU18817/00A patent/AU732426B2/en not_active Expired
- 1999-12-24 US US09/623,186 patent/US6699680B1/en not_active Expired - Lifetime
- 1999-12-24 EP EP99962461A patent/EP1058830B1/en not_active Expired - Lifetime
- 1999-12-24 NZ NZ506590A patent/NZ506590A/xx not_active IP Right Cessation
- 1999-12-24 WO PCT/GB1999/004428 patent/WO2000039559A2/en active Application Filing
-
2002
- 2002-12-26 US US10/329,608 patent/US20030138871A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0010526A1 (en) * | 1978-09-07 | 1980-04-30 | SALUS ISTITUTO DIAGNOSTICO DI CROCE' DR.FRANCESCO & C. s.a.s. | Method and apparatus for investigating haemocoagulation or aggregation of platelets |
Non-Patent Citations (1)
| Title |
|---|
| "A METHOD FOR THE PRODUCTION OF N2 MICROBUBBLES IN...." UNDERSEA BIO.RES. VOL.13,NO.3,SEPT 1986, PAGES 273,274,281 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US6699680B1 (en) | 2004-03-02 |
| EP1058830B1 (en) | 2012-07-11 |
| EP1058830A1 (en) | 2000-12-13 |
| JP4402301B2 (ja) | 2010-01-20 |
| WO2000039559A2 (en) | 2000-07-06 |
| EP2322910A2 (en) | 2011-05-18 |
| US20030138871A1 (en) | 2003-07-24 |
| EP2322910B1 (en) | 2019-03-13 |
| JP2002533712A (ja) | 2002-10-08 |
| WO2000039559A3 (en) | 2000-11-09 |
| EP2322910A3 (en) | 2012-02-01 |
| AU1881700A (en) | 2000-07-31 |
| NZ506590A (en) | 2002-10-25 |
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| Lines | COULTER ELECTRONICS LTD., NORTHWELL DRIVE, LUTON, BEDS. LU3 3RH, UK |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |