AU731704B2 - Oral composition comprising a triazole antifungal compound - Google Patents

Oral composition comprising a triazole antifungal compound Download PDF

Info

Publication number
AU731704B2
AU731704B2 AU33874/97A AU3387497A AU731704B2 AU 731704 B2 AU731704 B2 AU 731704B2 AU 33874/97 A AU33874/97 A AU 33874/97A AU 3387497 A AU3387497 A AU 3387497A AU 731704 B2 AU731704 B2 AU 731704B2
Authority
AU
Australia
Prior art keywords
composition
beads
antifungal compound
surfactant
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU33874/97A
Other languages
English (en)
Other versions
AU3387497A (en
Inventor
Ping I. Lee
Surendra A. Sangekar
Winston A. Vadino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU3387497A publication Critical patent/AU3387497A/en
Application granted granted Critical
Publication of AU731704B2 publication Critical patent/AU731704B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AU33874/97A 1996-06-28 1997-06-25 Oral composition comprising a triazole antifungal compound Ceased AU731704B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67243296A 1996-06-28 1996-06-28
US08/672432 1996-06-28
PCT/US1997/010122 WO1998000116A1 (en) 1996-06-28 1997-06-25 Oral composition comprising a triazole antifungal compound

Publications (2)

Publication Number Publication Date
AU3387497A AU3387497A (en) 1998-01-21
AU731704B2 true AU731704B2 (en) 2001-04-05

Family

ID=24698529

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33874/97A Ceased AU731704B2 (en) 1996-06-28 1997-06-25 Oral composition comprising a triazole antifungal compound

Country Status (16)

Country Link
EP (1) EP0914100A1 (ja)
JP (1) JP2000514059A (ja)
KR (1) KR20000022294A (ja)
CN (1) CN1228693A (ja)
AU (1) AU731704B2 (ja)
BR (1) BR9710069A (ja)
CA (1) CA2258683C (ja)
CZ (1) CZ421498A3 (ja)
HU (1) HUP9903869A3 (ja)
IL (1) IL127780A0 (ja)
NO (1) NO986087L (ja)
NZ (1) NZ333514A (ja)
PL (1) PL330864A1 (ja)
SK (1) SK177598A3 (ja)
TR (1) TR199802718T2 (ja)
WO (1) WO1998000116A1 (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0969821T1 (en) * 1997-03-26 2003-10-31 Janssen Pharmaceutica N.V. Pellets having a core coated with an antifungal and a polymer
WO1999063971A1 (en) * 1998-06-11 1999-12-16 Em Industries, Inc. Micro-osmotic controlled drug delivery systems
BR9906712A (pt) * 1998-07-17 2000-10-10 Janssen Pharmaceutica Nv Péletes que apresentam um núcleo revestido com um antifúngico e um polìmero
ES2157731B1 (es) * 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
FR2795961B1 (fr) * 1999-07-09 2004-05-28 Ethypharm Lab Prod Ethiques Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation
US7863331B2 (en) 1999-07-09 2011-01-04 Ethypharm Pharmaceutical composition containing fenofibrate and method for the preparation thereof
KR100694667B1 (ko) * 1999-12-08 2007-03-14 동아제약주식회사 생체내이용률 향상과 개인간 및 개인내 흡수 편차를감소시킨 이트라코나졸 함유 항진균성 제제
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
EP1842532A3 (en) * 2001-02-06 2009-04-22 Stiefel Laboratories, Inc. Oral sparingly water-soluble antifungal formulations and methods of making the same
FR2842736B1 (fr) 2002-07-26 2005-07-22 Flamel Tech Sa Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s)
ITMI20031096A1 (it) * 2003-05-30 2004-11-30 Eurand Spa Microcapsule per coacervazione contenenti farmaco incorporato nel polimero di rivestimento
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
CN105949278B (zh) * 2016-03-30 2019-12-06 南京曼杰生物科技有限公司 一种取代的四氢呋喃水溶性衍生物及其应用
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005263A1 (en) * 1992-09-03 1994-03-17 Janssen Pharmaceutica N.V. Beads having a core coated with an antifungal and a polymer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
CZ294823B6 (cs) * 1993-12-21 2005-03-16 Schering Corporation Fungicidní tetrahydrofurany

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005263A1 (en) * 1992-09-03 1994-03-17 Janssen Pharmaceutica N.V. Beads having a core coated with an antifungal and a polymer

Also Published As

Publication number Publication date
CA2258683A1 (en) 1998-01-08
NO986087L (no) 1999-02-26
CN1228693A (zh) 1999-09-15
PL330864A1 (en) 1999-06-07
BR9710069A (pt) 1999-08-10
HUP9903869A3 (en) 2000-07-28
EP0914100A1 (en) 1999-05-12
HUP9903869A2 (hu) 2000-06-28
JP2000514059A (ja) 2000-10-24
NO986087D0 (no) 1998-12-23
AU3387497A (en) 1998-01-21
IL127780A0 (en) 1999-10-28
NZ333514A (en) 2000-05-26
CZ421498A3 (cs) 1999-06-16
CA2258683C (en) 2007-07-31
WO1998000116A1 (en) 1998-01-08
SK177598A3 (en) 1999-07-12
KR20000022294A (ko) 2000-04-25
TR199802718T2 (xx) 1999-03-22

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired