AU730859B2 - Methods of preforming homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof - Google Patents
Methods of preforming homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof Download PDFInfo
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- AU730859B2 AU730859B2 AU79848/98A AU7984898A AU730859B2 AU 730859 B2 AU730859 B2 AU 730859B2 AU 79848/98 A AU79848/98 A AU 79848/98A AU 7984898 A AU7984898 A AU 7984898A AU 730859 B2 AU730859 B2 AU 730859B2
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Classifications
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/202—Pseudochromosomes, minichrosomosomes of bacteriophage origin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
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- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
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- Biodiversity & Conservation Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/880,966 US6143566A (en) | 1997-06-23 | 1997-06-23 | Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof |
| US08/880966 | 1997-06-23 | ||
| US10249098A | 1998-06-22 | 1998-06-22 | |
| US09/102490 | 1998-06-22 | ||
| PCT/US1998/012966 WO1998059060A1 (en) | 1997-06-23 | 1998-06-23 | Methods of preforming homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof |
Publications (2)
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| AU7984898A AU7984898A (en) | 1999-01-04 |
| AU730859B2 true AU730859B2 (en) | 2001-03-15 |
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| AU79848/98A Ceased AU730859B2 (en) | 1997-06-23 | 1998-06-23 | Methods of preforming homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof |
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|---|---|
| EP (1) | EP0998574A1 (ja) |
| JP (1) | JP2002515764A (ja) |
| AU (1) | AU730859B2 (ja) |
| CA (1) | CA2294619A1 (ja) |
| WO (1) | WO1998059060A1 (ja) |
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| US6156574A (en) | 1997-06-23 | 2000-12-05 | The Rockefeller University | Methods of performing gene trapping in bacterial and bacteriophage-derived artificial chromosomes and use thereof |
| US6821759B1 (en) | 1997-06-23 | 2004-11-23 | The Rockefeller University | Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof |
| US6355412B1 (en) | 1999-07-09 | 2002-03-12 | The European Molecular Biology Laboratory | Methods and compositions for directed cloning and subcloning using homologous recombination |
| AU6229800A (en) * | 1999-07-20 | 2001-02-05 | Rockefeller University, The | Conditional homologous recombination of large genomic vector inserts |
| WO2002002782A1 (en) * | 2000-06-29 | 2002-01-10 | The Rockefeller University | Activation of gene expression in cloned eukaryotic genomic dna and methods of use thereof |
| JP5670755B2 (ja) | 2008-03-12 | 2015-02-18 | ザ ロックフェラー ユニバーシティ | 翻訳プロファイリング及び分子表現型解析のための方法及び組成物 |
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1998
- 1998-06-23 AU AU79848/98A patent/AU730859B2/en not_active Ceased
- 1998-06-23 CA CA002294619A patent/CA2294619A1/en not_active Abandoned
- 1998-06-23 WO PCT/US1998/012966 patent/WO1998059060A1/en not_active Application Discontinuation
- 1998-06-23 JP JP50494899A patent/JP2002515764A/ja active Pending
- 1998-06-23 EP EP98930459A patent/EP0998574A1/en not_active Withdrawn
Non-Patent Citations (3)
| Title |
|---|
| CHROMOSOMA 7:479-488 (1996) * |
| CRITICAL REVIEWS IN MICROBIOLOGY 20:125-142 (1994) * |
| PROC. NATL. ACAD. SCI. U.S.A. 93:3094-3098 (1996) * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998059060A1 (en) | 1998-12-30 |
| EP0998574A1 (en) | 2000-05-10 |
| JP2002515764A (ja) | 2002-05-28 |
| AU7984898A (en) | 1999-01-04 |
| CA2294619A1 (en) | 1998-12-30 |
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