AU7221698A - Light imaging contrast agents - Google Patents

Light imaging contrast agents

Info

Publication number
AU7221698A
AU7221698A AU72216/98A AU7221698A AU7221698A AU 7221698 A AU7221698 A AU 7221698A AU 72216/98 A AU72216/98 A AU 72216/98A AU 7221698 A AU7221698 A AU 7221698A AU 7221698 A AU7221698 A AU 7221698A
Authority
AU
Australia
Prior art keywords
contrast agents
light imaging
imaging contrast
light
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72216/98A
Other languages
English (en)
Inventor
Edward Bacon
Vinay Chandrakant Desai
Paul Mark Henrichs
Gregory Lynn Mcintire
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed Imaging AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/984,771 external-priority patent/US6159445A/en
Priority claimed from GBGB9727124.1A external-priority patent/GB9727124D0/en
Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS
Publication of AU7221698A publication Critical patent/AU7221698A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043Fluorescein, used in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A61K41/0033Sonodynamic cancer therapy with sonochemically active agents or sonosensitizers, having their cytotoxic effects enhanced through application of ultrasounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • A61K49/0034Indocyanine green, i.e. ICG, cardiogreen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052Small organic molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/006Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461Dispersions, colloids, emulsions or suspensions
    • A61K49/0466Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0476Particles, beads, capsules, spheres
    • A61K49/0485Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU72216/98A 1997-04-29 1998-04-29 Light imaging contrast agents Abandoned AU7221698A (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US84858697A 1997-04-29 1997-04-29
US08848586 1997-04-29
US08984771 1997-12-04
US08/984,771 US6159445A (en) 1994-07-20 1997-12-04 Light imaging contrast agents
GB9727124 1997-12-22
GBGB9727124.1A GB9727124D0 (en) 1997-12-22 1997-12-22 Compounds
US3528598A 1998-03-05 1998-03-05
US09035285 1998-03-05
PCT/GB1998/001248 WO1998048846A1 (en) 1997-04-29 1998-04-29 Light imaging contrast agents

Publications (1)

Publication Number Publication Date
AU7221698A true AU7221698A (en) 1998-11-24

Family

ID=27451736

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72216/98A Abandoned AU7221698A (en) 1997-04-29 1998-04-29 Light imaging contrast agents

Country Status (4)

Country Link
EP (1) EP0979107A1 (ja)
JP (1) JP2001526650A (ja)
AU (1) AU7221698A (ja)
WO (1) WO1998048846A1 (ja)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6217848B1 (en) 1999-05-20 2001-04-17 Mallinckrodt Inc. Cyanine and indocyanine dye bioconjugates for biomedical applications
US7790144B2 (en) 2000-01-18 2010-09-07 Mallinckrodt Inc. Receptor-avid exogenous optical contrast and therapeutic agents
US6395257B1 (en) * 2000-01-18 2002-05-28 Mallinckrodt Inc. Dendrimer precursor dyes for imaging
EP1263447B1 (en) * 2000-02-08 2013-06-26 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
US6748259B1 (en) 2000-06-15 2004-06-08 Spectros Corporation Optical imaging of induced signals in vivo under ambient light conditions
WO2002038190A2 (en) 2000-10-27 2002-05-16 Beth Israel Deaconess Medical Center Non-isotopic detection of osteoblastic activity in vivo using modified bisphosphonates
JP4241038B2 (ja) 2000-10-30 2009-03-18 ザ ジェネラル ホスピタル コーポレーション 組織分析のための光学的な方法及びシステム
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
US6761878B2 (en) 2001-10-17 2004-07-13 Mallinckrodt, Inc. Pathological tissue detection and treatment employing targeted benzoindole optical agents
US20030105300A1 (en) 2001-10-17 2003-06-05 Mallinckrodt Inc. Tumor targeted photodiagnostic-phototherapeutic agents
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
CA2519937C (en) 2003-03-31 2012-11-20 Guillermo J. Tearney Speckle reduction in optical coherence tomography by path length encoded angular compounding
WO2005000218A2 (en) 2003-05-31 2005-01-06 Washington University Macrocyclic cyanine and indocyanine bioconjugates provide improved biomedical applications
CA2527930C (en) 2003-06-06 2014-08-19 The General Hospital Corporation Process and apparatus for a wavelength tuning source
EP3009815B1 (en) 2003-10-27 2022-09-07 The General Hospital Corporation Method and apparatus for performing optical imaging using frequency-domain interferometry
EP1771755B1 (en) 2004-07-02 2016-09-21 The General Hospital Corporation Endoscopic imaging probe comprising dual clad fibre
EP1782020B1 (en) 2004-08-06 2012-10-03 The General Hospital Corporation Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
WO2006024014A2 (en) 2004-08-24 2006-03-02 The General Hospital Corporation Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample
KR20120062944A (ko) 2004-08-24 2012-06-14 더 제너럴 하스피탈 코포레이션 혈관절편 영상화 방법 및 장치
EP2302364A3 (en) 2004-09-10 2011-04-06 The General Hospital Corporation System and method for optical coherence imaging
EP2329759B1 (en) 2004-09-29 2014-03-12 The General Hospital Corporation System and method for optical coherence imaging
JP4597744B2 (ja) 2004-11-08 2010-12-15 株式会社トプコン 光画像計測装置及び光画像計測方法
EP1825214A1 (en) 2004-11-24 2007-08-29 The General Hospital Corporation Common-path interferometer for endoscopic oct
EP1816949A1 (en) 2004-11-29 2007-08-15 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
EP1875436B1 (en) 2005-04-28 2009-12-09 The General Hospital Corporation Evaluation of image features of an anatomical structure in optical coherence tomography images
WO2006130802A2 (en) 2005-06-01 2006-12-07 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
EP1745739A3 (en) 2005-07-14 2009-04-22 Bundesrepublik Deutschland, vertr. d.d. Bundes- ministerium f. Wirtschaft- und Technologie, dieses vertr. d.d. Präs. d. Phys.-Techn. Bundesanstalt Optical imaging of rheumatoid arthritis
EP1913332B1 (en) 2005-08-09 2010-10-13 The General Hospital Corporation Apparatus and method for performing polarization-based quadrature demodulation in optical coherence tomography
KR20080066705A (ko) 2005-09-29 2008-07-16 더 제너럴 하스피탈 코포레이션 점진적으로 증가하는 분해능을 이용하여 하나 이상의 생물학적 샘플을 관찰 및 분석하기 위한 방법 및 장치
ES2627998T3 (es) * 2005-11-16 2017-08-01 Exchange Imaging Technologies Gmbh Nanopartículas fluorescentes
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
JP5384944B2 (ja) 2006-01-19 2014-01-08 ザ ジェネラル ホスピタル コーポレイション ビームスキャニングによる上皮性管腔器官の光学的撮像システム
EP2659852A3 (en) 2006-02-01 2014-01-15 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
EP1983921B1 (en) 2006-02-01 2016-05-25 The General Hospital Corporation Systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
WO2007092911A2 (en) 2006-02-08 2007-08-16 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
JP2007223966A (ja) * 2006-02-24 2007-09-06 Pentax Corp 細胞表面又は組織表面染色剤組成物及びこれを用いた染色方法
WO2007101026A2 (en) 2006-02-24 2007-09-07 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
US8175685B2 (en) 2006-05-10 2012-05-08 The General Hospital Corporation Process, arrangements and systems for providing frequency domain imaging of a sample
US7993927B2 (en) 2006-07-03 2011-08-09 Beth Israel Deaconess Medical Center, Inc. Histology methods
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
WO2008102065A1 (fr) * 2007-02-14 2008-08-28 Commissariat A L'energie Atomique Emulsions fluorescentes pour l'imagerie optique
WO2008116010A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome exemplary laser speckle imaging procedure
EP2132840A2 (en) 2007-03-23 2009-12-16 The General Hospital Corporation Methods, arrangements and apparatus for utlizing a wavelength-swept laser using angular scanning and dispersion procedures
WO2008121844A1 (en) 2007-03-30 2008-10-09 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
EP2173254A2 (en) 2007-07-31 2010-04-14 The General Hospital Corporation Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging
US20090214436A1 (en) 2008-02-18 2009-08-27 Washington University Dichromic fluorescent compounds
EP2288948A4 (en) 2008-06-20 2011-12-28 Gen Hospital Corp ARRANGEMENT OF CONDENSED GLASS FIBER COUPLERS AND METHOD FOR THEIR USE
US9254089B2 (en) 2008-07-14 2016-02-09 The General Hospital Corporation Apparatus and methods for facilitating at least partial overlap of dispersed ration on at least one sample
FR2934953B1 (fr) 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
US20100092390A1 (en) * 2008-10-09 2010-04-15 President And Fellows Of Harvard College Methods for Making Particles Having Long Spin-Lattice Relaxation Times
JP5731394B2 (ja) 2008-12-10 2015-06-10 ザ ジェネラル ホスピタル コーポレイション 光サブサンプリングを通じて、光コヒーレンストモグラヒィーのイメージング深度範囲を伸ばすためのシステム、装置及び方法
US9814417B2 (en) * 2009-01-13 2017-11-14 Longevity Link Corporation Noninvasive measurement of flavonoid compounds in biological tissue
EP2389093A4 (en) 2009-01-20 2013-07-31 Gen Hospital Corp APPARATUS, SYSTEM AND METHOD FOR ENDOSCOPIC BIOPSY
WO2010105197A2 (en) 2009-03-12 2010-09-16 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measuring at least one mechanical property of tissue using coherent speckle techniques(s)
WO2011008822A2 (en) 2009-07-14 2011-01-20 The General Hospital Corporation Apparatus, systems and methods for measuring flow and pressure within a vessel
PT2542154T (pt) 2010-03-05 2020-11-25 Massachusetts Gen Hospital Aparelho para proporcionar radiação eletromagnética a uma amostra
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
JP5778762B2 (ja) 2010-05-25 2015-09-16 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィー画像のスペクトル解析のための装置及び方法
US9557154B2 (en) 2010-05-25 2017-01-31 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
WO2011153434A2 (en) 2010-06-03 2011-12-08 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
WO2012026608A1 (en) * 2010-08-24 2012-03-01 Canon Kabushiki Kaisha Polymeric particle and hydrophilic dye having a sulfonate group encapsulated within the particle
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
US9330092B2 (en) 2011-07-19 2016-05-03 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
EP3835718B1 (en) 2011-08-25 2023-07-26 The General Hospital Corporation Apparatus for providing micro-optical coherence tomography inside a respiratory system
JP2015502562A (ja) 2011-10-18 2015-01-22 ザ ジェネラル ホスピタル コーポレイション 再循環光学遅延を生成および/または提供するための装置および方法
EP3553075A1 (en) 2012-01-23 2019-10-16 Washington University Goggle imaging systems and methods
WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
EP2852315A4 (en) 2012-05-21 2016-06-08 Gen Hospital Corp DEVICE, APPARATUS AND METHOD FOR CAPSULE MICROSCOPY
US9968261B2 (en) 2013-01-28 2018-05-15 The General Hospital Corporation Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging
WO2014120791A1 (en) 2013-01-29 2014-08-07 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
WO2014144709A2 (en) 2013-03-15 2014-09-18 The General Hospital Corporation Methods and systems for characterizing an object
US9784681B2 (en) 2013-05-13 2017-10-10 The General Hospital Corporation System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence
EP3021735A4 (en) 2013-07-19 2017-04-19 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
EP3692887B1 (en) 2013-07-19 2024-03-06 The General Hospital Corporation Imaging apparatus which utilizes multidirectional field of view endoscopy
US9668652B2 (en) 2013-07-26 2017-06-06 The General Hospital Corporation System, apparatus and method for utilizing optical dispersion for fourier-domain optical coherence tomography
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
WO2015153982A1 (en) 2014-04-04 2015-10-08 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
ES2907287T3 (es) 2014-07-25 2022-04-22 Massachusetts Gen Hospital Aparato para imagenología y diagnóstico in vivo
US10806804B2 (en) 2015-05-06 2020-10-20 Washington University Compounds having RD targeting motifs and methods of use thereof
EP4072598A4 (en) 2019-12-13 2024-02-21 Washington University St Louis NEAR-INFRARED FLUORESCENT DYES, FORMULATIONS AND ASSOCIATED METHODS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650135A (en) * 1994-07-01 1997-07-22 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
GB9502065D0 (en) * 1995-02-02 1995-03-22 Nycomed Imaging As Contrast media
HUP9900426A3 (en) * 1995-05-01 2001-12-28 Univ Pittsburgh Pittsburgh Amyloid binding azoderivatives, preparation thereof and use of these compounds for the antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid deposition

Also Published As

Publication number Publication date
JP2001526650A (ja) 2001-12-18
WO1998048846A1 (en) 1998-11-05
EP0979107A1 (en) 2000-02-16

Similar Documents

Publication Publication Date Title
AU7221698A (en) Light imaging contrast agents
AU7365098A (en) Light enhanced bullhorn
AU8275798A (en) Fluorescence imaging system
AU9103798A (en) Switchable optical components
AU2228197A (en) Optical shutter
AU8599598A (en) Imaging device
AUPO884297A0 (en) Imaging devices
AU5541998A (en) Light screening agent
AU4955297A (en) Optical images
AU5786498A (en) Optical device
GB9711366D0 (en) Optical imaging system
GB9702123D0 (en) Optical components
AU3949597A (en) Optical images
EP1039317A4 (en) OPTICAL FILM
GB9722250D0 (en) Optical components
AU7065198A (en) Light assembly
AU6641698A (en) Optical device
AU6105998A (en) Optical device
AU6129298A (en) Light fitting
AU9002098A (en) Optical device
AU5208798A (en) Light
AUPO634497A0 (en) Light fit
AU1899099A (en) Agents
AUPO462297A0 (en) Light
AUPM645694A0 (en) Light images

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase