AU714581B2 - Use of 2-(4-(azolylbutyl)piperazinyl-(methyl)benzimidazole derivatives for preparing drugs for treating or preventing asthma - Google Patents

Use of 2-(4-(azolylbutyl)piperazinyl-(methyl)benzimidazole derivatives for preparing drugs for treating or preventing asthma Download PDF

Info

Publication number
AU714581B2
AU714581B2 AU42611/96A AU4261196A AU714581B2 AU 714581 B2 AU714581 B2 AU 714581B2 AU 42611/96 A AU42611/96 A AU 42611/96A AU 4261196 A AU4261196 A AU 4261196A AU 714581 B2 AU714581 B2 AU 714581B2
Authority
AU
Australia
Prior art keywords
methyl
azolylbutyl
piperazinyl
treating
benzimidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU42611/96A
Other languages
English (en)
Other versions
AU4261196A (en
Inventor
Maria Rosa Cuberes-Altisent
Jordi Frigola-Constansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of AU4261196A publication Critical patent/AU4261196A/en
Application granted granted Critical
Publication of AU714581B2 publication Critical patent/AU714581B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU42611/96A 1994-12-08 1995-12-06 Use of 2-(4-(azolylbutyl)piperazinyl-(methyl)benzimidazole derivatives for preparing drugs for treating or preventing asthma Ceased AU714581B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/14766 1994-12-08
FR9414766A FR2727865B1 (fr) 1994-12-08 1994-12-08 Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
PCT/EP1995/004884 WO1996017609A1 (fr) 1994-12-08 1995-12-06 Utilisation des derives de 2-[4-(azolylbutyl)piperazinyl(methyl)] benzimidazole pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme

Publications (2)

Publication Number Publication Date
AU4261196A AU4261196A (en) 1996-06-26
AU714581B2 true AU714581B2 (en) 2000-01-06

Family

ID=9469596

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42611/96A Ceased AU714581B2 (en) 1994-12-08 1995-12-06 Use of 2-(4-(azolylbutyl)piperazinyl-(methyl)benzimidazole derivatives for preparing drugs for treating or preventing asthma

Country Status (9)

Country Link
EP (1) EP0741571A1 (es)
JP (1) JPH09508923A (es)
AU (1) AU714581B2 (es)
BR (1) BR1100852A (es)
CA (1) CA2182904A1 (es)
ES (1) ES2105986B1 (es)
FR (1) FR2727865B1 (es)
WO (1) WO1996017609A1 (es)
ZA (1) ZA9510435B (es)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200641A (en) * 1976-12-21 1980-04-29 Janssen Pharmaceutica, N.V. 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
US5182280A (en) * 1990-07-26 1993-01-26 Laboratorios Del Dr. Esteve, S. A. Derivatives of benzimidazole and their use as antihistamines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0383924A (ja) * 1989-08-28 1991-04-09 Kanebo Ltd 経皮投与用組成物
FR2668150B1 (fr) * 1990-10-17 1994-11-18 Theramex Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
FR2674856B1 (fr) * 1991-04-05 1993-07-30 Esteve Labor Dr Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200641A (en) * 1976-12-21 1980-04-29 Janssen Pharmaceutica, N.V. 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
US5182280A (en) * 1990-07-26 1993-01-26 Laboratorios Del Dr. Esteve, S. A. Derivatives of benzimidazole and their use as antihistamines

Also Published As

Publication number Publication date
ZA9510435B (en) 1996-06-14
EP0741571A1 (fr) 1996-11-13
FR2727865B1 (fr) 1997-07-18
CA2182904A1 (fr) 1996-06-13
WO1996017609A1 (fr) 1996-06-13
JPH09508923A (ja) 1997-09-09
BR1100852A (pt) 1999-10-13
ES2105986B1 (es) 1998-07-01
FR2727865A1 (fr) 1996-06-14
ES2105986A1 (es) 1997-10-16
AU4261196A (en) 1996-06-26

Similar Documents

Publication Publication Date Title
DE60027985T2 (de) Behandlung von Lungenhochdruck
TWI272106B (en) New medicament compositions based on anticholinergically-effective compounds and beta-mimetics
DD210276A5 (de) Verfahren zur herstellung von 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkylnorscopinether
JPH05507083A (ja) イミダゾリンの吸入による慢性閉塞性肺疾患(copd)の治療
CN111936124A (zh) 一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用
JPH09506622A (ja) α−2−アドレノセプター作動剤として有用な6−(2−イミダゾリニルアミノ)キノキサリン化合物
EP2254581A1 (en) Pteridine derivatives for treating respiratory disease
AU714581B2 (en) Use of 2-(4-(azolylbutyl)piperazinyl-(methyl)benzimidazole derivatives for preparing drugs for treating or preventing asthma
US6946486B2 (en) Quaternary ammonium compounds
US6951950B2 (en) Quaternary ammonium compounds
US4097596A (en) Inhalation therapy for relieving bronchial spasm using quaternary salts of promethazine
EP2080507A1 (en) Pharmaceutical formulations comprising an anticholinergic drug
CN111971034A (zh) 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用
JPS62294614A (ja) ベンゾ〔c〕〔1,6〕ナフチリジン誘導体からなる新規医薬組成物
EP1562599A1 (en) Quaternary ammonium compounds as muscarinic receptor antagonists
MXPA05003398A (es) Compuestos de amonio cuaternario.
WO2023225177A1 (en) Methods and pharmaceutical compositions to treat respiratory depression in patients
US4010269A (en) Antiviral quinazoline compositions and methods of use
JPH06192090A (ja) 抗喘息薬
EP0075029B1 (en) Agent for treating chronic obliterative lung disease
DE69523346T2 (de) Substituierte 6-h-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetisierende cardiovaskulare und hypometabole mittel, und eine sie enthaltende pharmazeutische zubereitung
Nishino Effects of Hypercapnia on Nasal Reflex Responses Elicited by Nasal Insufflation of Isoflurane in Lightly-Anesthetized Humans
CN118541153A (zh) 用于治疗睡眠呼吸暂停的task1/3通道阻断剂与去甲肾上腺素再摄取抑制剂的结合物
WO2005004875A1 (ja) 経肺投与用医薬組成物
JPH0873354A (ja) 気道過敏症および/または気道障害の予防、治療剤

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired