AU707211B2 - Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease - Google Patents

Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease Download PDF

Info

Publication number
AU707211B2
AU707211B2 AU66826/96A AU6682696A AU707211B2 AU 707211 B2 AU707211 B2 AU 707211B2 AU 66826/96 A AU66826/96 A AU 66826/96A AU 6682696 A AU6682696 A AU 6682696A AU 707211 B2 AU707211 B2 AU 707211B2
Authority
AU
Australia
Prior art keywords
cells
recipient
hematopoietic system
bone marrow
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU66826/96A
Other languages
English (en)
Other versions
AU6682696A (en
Inventor
Edmund K. Waller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emory University
Original Assignee
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Publication of AU6682696A publication Critical patent/AU6682696A/en
Application granted granted Critical
Publication of AU707211B2 publication Critical patent/AU707211B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22Immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/418Antigens related to induction of tolerance to non-self
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/50Cellular immunotherapy characterised by the use of allogeneic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU66826/96A 1995-11-08 1996-07-29 Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease Ceased AU707211B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/555520 1995-11-08
US08/555,520 US5800539A (en) 1995-11-08 1995-11-08 Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease
PCT/US1996/012426 WO1997017079A1 (en) 1995-11-08 1996-07-29 Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease

Publications (2)

Publication Number Publication Date
AU6682696A AU6682696A (en) 1997-05-29
AU707211B2 true AU707211B2 (en) 1999-07-08

Family

ID=24217573

Family Applications (1)

Application Number Title Priority Date Filing Date
AU66826/96A Ceased AU707211B2 (en) 1995-11-08 1996-07-29 Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease

Country Status (6)

Country Link
US (1) US5800539A (OSRAM)
EP (1) EP0862443A1 (OSRAM)
JP (1) JP2001509778A (OSRAM)
AU (1) AU707211B2 (OSRAM)
CA (1) CA2237200A1 (OSRAM)
WO (1) WO1997017079A1 (OSRAM)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409564B2 (en) 1999-10-05 2013-04-02 Universite De Montreal Rhodamine derivatives for photodynamic diagnosis and treatment
DE60043511D1 (de) * 1999-10-20 2010-01-21 Chugai Pharmaceutical Co Ltd Verwendung von g-csf zur hemmung der gvhd
AU2001292564A1 (en) * 2000-08-31 2002-03-13 Emory University A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease
US6869956B2 (en) 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
EP1361896A2 (en) * 2001-01-23 2003-11-19 Boston Scientific Corporation Localized myocardial injection method for treating ischemic myocardium
JP2004528021A (ja) 2001-02-14 2004-09-16 アンスロジェネシス コーポレーション 分娩後の哺乳動物の胎盤、その使用およびそれに由来する胎盤幹細胞
CA2342675A1 (en) * 2001-04-02 2002-10-02 Abdelkrim Habi Halogenated rhodamine derivatives and applications thereof
WO2003001981A2 (en) * 2001-06-29 2003-01-09 The Government Of The United State Of America As Represent By The Secretary Of The Department Of Health And Human Services Method of promoting engraftment of a donor transplant in a recipient host
US7037900B2 (en) * 2001-10-12 2006-05-02 Supergen, Inc. Composition and method for treating graft-versus-host disease
US7799324B2 (en) * 2001-12-07 2010-09-21 Geron Corporation Using undifferentiated embryonic stem cells to control the immune system
US20040224403A1 (en) * 2001-12-07 2004-11-11 Robarts Research Institute Reconstituting hematopoietic cell function using human embryonic stem cells
NZ579705A (en) 2002-02-13 2011-07-29 Anthrogenesis Corp Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
CA105900S (en) 2003-08-12 2006-10-19 180S Inc Frame for ear warmer
JP4901479B2 (ja) * 2003-12-05 2012-03-21 ユニヴェルシテ ドゥ モントリオール 免疫疾患、感染症および癌の阻止、保護、予防または治療のための免疫学的化合物
JP2006081542A (ja) * 2004-08-18 2006-03-30 Institute Of Physical & Chemical Research クローン哺乳動物の作成方法
WO2006057951A2 (en) * 2004-11-22 2006-06-01 Beth Israel Deaconess Medical Center Methods and compositions for the treatment of graft failure
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス,インコーポレイティド 神経発生のgaba受容体媒介調節
PT2471905T (pt) 2005-12-29 2019-01-11 Celularity Inc Populações de células estaminais placentárias
AU2006332679A1 (en) 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
US20090197823A1 (en) 2006-05-09 2009-08-06 Braincells, Inc. Aliskiren modulation of neurogenesis
US7998971B2 (en) 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
CN101631852A (zh) 2006-10-23 2010-01-20 人类起源公司 用胎盘细胞群治疗骨缺损的方法和组合物
WO2008083204A2 (en) * 2006-12-28 2008-07-10 Braincells, Inc. Modulation of neurogenesis by melatoninergic ligands
WO2008086483A2 (en) * 2007-01-11 2008-07-17 Braincells, Inc. Modulation of neurogenesis with use of modafinil
WO2008097861A2 (en) * 2007-02-02 2008-08-14 Braincells, Inc. MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS
WO2009123877A1 (en) * 2008-03-21 2009-10-08 Braincells, Inc. A method of treating a nervous system disorder by modulation of neurogenesis with mcc-257
CA2965883C (en) 2008-08-22 2020-05-12 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
WO2012092485A1 (en) 2010-12-31 2012-07-05 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
WO2012166844A2 (en) 2011-06-01 2012-12-06 Anthrogenesis Corporation Treatment of pain using placental stem cells
WO2023277114A1 (ja) * 2021-07-02 2023-01-05 公益財団法人神戸医療産業都市推進機構 放射線照射造血幹細胞を含む医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4869826A (en) * 1987-09-01 1989-09-26 Process Biotechnology, Inc. Cellular adsorbents for removal of viral contaminants from blood and complex protein solutions
US5147289A (en) * 1990-03-29 1992-09-15 Therakos, Inc Non-specific immune system enhancement
WO1992010198A1 (en) * 1990-12-06 1992-06-25 Johnson & Johnson Research Pty Limited Immunotherapeutic agents, compositions and methods
US5601815A (en) * 1992-08-21 1997-02-11 Schering Corp IL-4 and IL-10 to downregulate delayed-type hypersensitivity and cytokine expresion by T-cells
JP3541950B2 (ja) * 1993-05-14 2004-07-14 ザ・ウイスター・インステイテユート・オブ・アナトミー・アンド・バイオロジー 癌およびウイルス性疾患を治療するための改変化tall−104細胞の使用
IL107483A0 (en) * 1993-11-03 1994-02-27 Yeda Res & Dev Bone marrow transplantation
IL112969A (en) * 1994-03-17 2001-05-20 Baxter Int Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator

Also Published As

Publication number Publication date
JP2001509778A (ja) 2001-07-24
CA2237200A1 (en) 1997-05-15
EP0862443A1 (en) 1998-09-09
WO1997017079A1 (en) 1997-05-15
US5800539A (en) 1998-09-01
AU6682696A (en) 1997-05-29

Similar Documents

Publication Publication Date Title
AU707211B2 (en) Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease
Thomas Bone marrow transplantation: a historical review
US5443983A (en) Method of culturing lymphocytes and method of treatment using such lymphocytes
Andrews et al. The ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboons
US7381563B2 (en) Use of cytokines and mitogens to inhibit graft versus host disease
US5308626A (en) Lymphokine activated effector cells for antibody-dependent cellular cytotoxicity (ADCC) treatment of cancer and other diseases
US5928639A (en) Immunotherapy of cancer with allogeneic lymphocytes
KR101900807B1 (ko) 헬퍼 t1 특성들 및 세포용해 특성들을 발현하는 세포들
Fagan et al. Immunotherapy for cancer: the use of lymphokine activated killer (LAK) cells
US20030149011A1 (en) Methods and reagents for extracorporeal immunomodulatory therapy
Arcese et al. Clinical use of allogeneic hematopoietic stem cells from sources other than bone marrow
Takaue Peripheral blood stem cell autografts in children with acute lymphoblastic leukemia and lymphoma: updated experience
US6213127B1 (en) Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity
CA2162732C (en) Use of modified tall-104 cells to treat cancer and viral diseases
US5702702A (en) Modified cytotoxic tall cell line and compositions and methods for manufacture and use thereof as therapeutic reagents for cancer
US20010014320A1 (en) Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity
JP2002501726A (ja) 抗原提示および免疫応答を高める、改善された体外方法
WO2001070243A2 (en) A method for treating early breast cancer
Kolb et al. Tolerance and chimerism1
MAckIE et al. Dose-related mechanisms of immunosuppression mediated by murine anti-CD3 monoclonal antibody in pancreatic islet cell transplantation and delayed-type hypersensitivity
Migliori et al. Lymphokine-activated killer (LAK) cells can be focused at sites of tumor growth by products of macrophage activation
JP2003508047A (ja) 移植片−対−宿主疾患を抑制するサイトカイン、細胞およびマイトジェンの使用
CN116135969A (zh) 从外周血中扩增及产生细胞因子诱导的杀伤细胞群的方法
JP4106488B2 (ja) 同種移植片に対する免疫寛容の誘導および/または白血病処置のための、幹細胞およびcd6枯渇幹細胞の使用
Bouwens Pit cells