AU666357B2 - Indole or benzimidazole derivatives - Google Patents
Indole or benzimidazole derivatives Download PDFInfo
- Publication number
- AU666357B2 AU666357B2 AU35718/93A AU3571893A AU666357B2 AU 666357 B2 AU666357 B2 AU 666357B2 AU 35718/93 A AU35718/93 A AU 35718/93A AU 3571893 A AU3571893 A AU 3571893A AU 666357 B2 AU666357 B2 AU 666357B2
- Authority
- AU
- Australia
- Prior art keywords
- dihydro
- oxo
- methyl
- carboxylate
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929204565A GB9204565D0 (en) | 1992-03-03 | 1992-03-03 | Pharmaceuticals |
| GB9204565 | 1992-03-03 | ||
| PCT/GB1993/000395 WO1993018027A1 (en) | 1992-03-03 | 1993-02-25 | Nitrogen containing heterocyclic compounds useful as pharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU3571893A AU3571893A (en) | 1993-10-05 |
| AU666357B2 true AU666357B2 (en) | 1996-02-08 |
Family
ID=10711400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU35718/93A Ceased AU666357B2 (en) | 1992-03-03 | 1993-02-25 | Indole or benzimidazole derivatives |
Country Status (11)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
| WO1994008965A1 (en) * | 1992-10-16 | 1994-04-28 | Smithkline Beecham Plc | N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-ht4 receptor antagonists |
| GB9310582D0 (en) * | 1993-05-22 | 1993-07-07 | Smithkline Beecham Plc | Pharmaceuticals |
| IT1275903B1 (it) * | 1995-03-14 | 1997-10-24 | Boehringer Ingelheim Italia | Esteri e ammidi della 1,4-piperidina disostituita |
| IL138568A0 (en) * | 1998-04-28 | 2001-10-31 | Dainippon Pharmaceutical Co | 1-[(1-substituted-4-piperidinyl) methyl] -4- piperidine derivative, process for the preparation thereof, pharmaceutical composition containing the same and intermediate therefor |
| BRPI0414105B8 (pt) * | 2003-09-03 | 2021-05-25 | Askat Inc | compostos de benzimidazolona com atividade agonista do receptor 5-ht4 |
| EA010891B9 (ru) | 2004-06-15 | 2012-08-30 | Пфайзер Инк. | Производные бензимидазолонкарбоновой кислоты |
| US7737163B2 (en) | 2004-06-15 | 2010-06-15 | Pfizer Inc. | Benzimidazolone carboxylic acid derivatives |
| AP2418A (en) * | 2004-06-15 | 2012-06-04 | Pfizer | Benzimidazolone carboxylic acid derivatives. |
| JP2008509088A (ja) * | 2004-09-02 | 2008-03-27 | ファイザー株式会社 | ベンズイミダゾロンカルボン酸誘導体 |
| EA012615B1 (ru) * | 2005-02-22 | 2009-10-30 | Пфайзер Инк. | Производные оксииндола в качестве агонистов 5-htрецептора |
| ES2357362T3 (es) | 2005-03-15 | 2011-04-25 | Pfizer, Inc. | Derivados de bencimidazolona como ligandos del receptor cb2. |
| US8592427B2 (en) | 2010-06-24 | 2013-11-26 | Alkermes Pharma Ireland Limited | Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2053451T3 (es) * | 1986-01-07 | 1994-08-01 | Beecham Group Plc | Un procedimiento para la preparacion de un compuesto que tiene propiedades farmacologicas utiles. |
| IT1231413B (it) * | 1987-09-23 | 1991-12-04 | Angeli Inst Spa | Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht |
-
1992
- 1992-03-03 GB GB929204565A patent/GB9204565D0/en active Pending
-
1993
- 1993-02-25 JP JP5515422A patent/JPH07504428A/ja active Pending
- 1993-02-25 AU AU35718/93A patent/AU666357B2/en not_active Ceased
- 1993-02-25 NZ NZ249217A patent/NZ249217A/en unknown
- 1993-02-25 WO PCT/GB1993/000395 patent/WO1993018027A1/en not_active Application Discontinuation
- 1993-02-25 CA CA002131381A patent/CA2131381A1/en not_active Abandoned
- 1993-02-25 EP EP93904259A patent/EP0629198A1/en not_active Withdrawn
- 1993-03-01 ZA ZA931430A patent/ZA931430B/xx unknown
- 1993-03-02 MX MX9301157A patent/MX9301157A/es unknown
- 1993-03-20 TW TW082102087A patent/TW279857B/zh active
-
1994
- 1994-09-02 KR KR1019940703105A patent/KR950700285A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU3571893A (en) | 1993-10-05 |
| NZ249217A (en) | 1996-06-25 |
| KR950700285A (ko) | 1995-01-16 |
| WO1993018027A1 (en) | 1993-09-16 |
| CA2131381A1 (en) | 1993-09-16 |
| MX9301157A (es) | 1994-07-29 |
| TW279857B (enrdf_load_html_response) | 1996-07-01 |
| GB9204565D0 (en) | 1992-04-15 |
| EP0629198A1 (en) | 1994-12-21 |
| JPH07504428A (ja) | 1995-05-18 |
| ZA931430B (en) | 1993-10-22 |
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