AU663523B2 - Triazoloquinoxalin-1,4-diones and their preparation and use - Google Patents

Triazoloquinoxalin-1,4-diones and their preparation and use Download PDF

Info

Publication number
AU663523B2
AU663523B2 AU26600/92A AU2660092A AU663523B2 AU 663523 B2 AU663523 B2 AU 663523B2 AU 26600/92 A AU26600/92 A AU 26600/92A AU 2660092 A AU2660092 A AU 2660092A AU 663523 B2 AU663523 B2 AU 663523B2
Authority
AU
Australia
Prior art keywords
compound
formula
pct
international
defined above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU26600/92A
Other languages
English (en)
Other versions
AU2660092A (en
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU2660092A publication Critical patent/AU2660092A/en
Application granted granted Critical
Publication of AU663523B2 publication Critical patent/AU663523B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU26600/92A 1991-09-20 1992-09-09 Triazoloquinoxalin-1,4-diones and their preparation and use Ceased AU663523B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK911624A DK162491D0 (da) 1991-09-20 1991-09-20 Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
DK1624/91 1991-09-20
PCT/DK1992/000271 WO1993006103A1 (en) 1991-09-20 1992-09-09 Triazoloquinoxalin-1,4-diones and their preparation and use

Publications (2)

Publication Number Publication Date
AU2660092A AU2660092A (en) 1993-04-27
AU663523B2 true AU663523B2 (en) 1995-10-12

Family

ID=8106648

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26600/92A Ceased AU663523B2 (en) 1991-09-20 1992-09-09 Triazoloquinoxalin-1,4-diones and their preparation and use

Country Status (13)

Country Link
US (1) US5504085A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0633885A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH07501791A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU663523B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2119579A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK162491D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI106719B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL103160A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO302368B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ244398A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW210341B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1993006103A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA927172B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08509747A (ja) * 1993-05-06 1996-10-15 ノボ ノルディスク アクティーゼルスカルブ 〔１，２，４〕トリアゾロ〔４，３−ａ〕キノキサリン化合物、それらの製造および使用
DE69516128T2 (de) * 1994-02-14 2000-12-21 Merrell Pharmaceuticals Inc., Cincinnati Mercaptoacetylamid-1,3,4,5-tetrahydrobenzo(c)azepin-3-ein disulfidderivate als enkephalinase und ace inhibitoren
FR2717813B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant .
FR2717812B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Indeno[1,2-e]pyrazine-4-ones, leur préparation et les médicaments les contenant.
FR2717805B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .
FR2717814B1 (fr) * 1994-03-28 1996-04-26 Rhone Poulenc Rorer Sa Dérivés de 1,2,4-triazolo(4,3-a)pyrazine-4-one, leur préparation et les médicaments les contenant.
FR2722789B1 (fr) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant
JPH10506620A (ja) * 1994-09-16 1998-06-30 ノボ ノルディスク アクティーゼルスカブ 〔１，２，４〕トリアゾロ〔４，３−ａ〕キノキサリノン誘導体、それらの調製方法及び使用
DE69515680T2 (de) * 1994-09-16 2000-10-19 Novo Nordisk A/S, Bagsvaerd [1,2,4]TRIAZOLO[4,3-a]CHINOXYLINONDERIVATE, IHRE DARSTELLUNG UND VERWENDUNG ALS ANTAGONISTEN VON AMPA-REZEPTOREN
US5679680A (en) * 1995-02-16 1997-10-21 Warner-Lambert Company α-substituted hydrazides having calpain inhibitory activity
USRE37234E1 (en) * 1996-11-01 2001-06-19 Nitromed, Inc. Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
US5958926A (en) 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
AU2007332440B2 (en) * 2006-12-13 2013-05-16 Aska Pharmaceutical Co., Ltd. Quinoxaline derivative
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
PT2615096T (pt) * 2010-09-07 2019-10-15 Astellas Pharma Inc Composto de quinoxalina
CN116535410B (zh) * 2023-04-25 2025-03-21 河北农业大学 一种三唑并喹唑啉酮类化合物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400382A (en) * 1980-05-09 1983-08-23 Usv Pharmaceutical Corporation Thiazoloquinoxalin-1,4-diones for treating allergy
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
US4623725A (en) * 1982-10-18 1986-11-18 Pfizer Inc. [1,2,4]Triazolo[4,3-a]quinoxaline-4-amine derivatives
US4780464A (en) * 1986-12-08 1988-10-25 Warner-Lambert Company (1,2,4)triazolo(4,3-a)quinoxaline-4-amines
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
US4975430A (en) * 1989-06-16 1990-12-04 The State Of Oregon Acting By And Through The State Board Of Education On Behalf Of The Oregon Health Sciences University CNQX and its analogs as therapeutics for degenerative neural diseases
US5283244A (en) * 1990-11-06 1994-02-01 Yamanouchi Pharmaceutical Co., Ltd. Fused pyrazine derivatives
PT101004B (pt) * 1991-10-26 1999-10-29 Schering Ag Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem
FR2690160A1 (fr) * 1992-04-15 1993-10-22 Rhone Poulenc Rorer Sa Application de dérivés d'acide 2H-1,2,4-benzothiadiazine-1,1-dioxyde-3-carboxylique à la préparation de médicaments, les produits nouveaux, leur préparation et les médicaments les contenant.

Also Published As

Publication number Publication date
NO302368B1 (no) 1998-02-23
ZA927172B (en) 1993-03-24
CA2119579A1 (en) 1993-04-01
FI106719B (fi) 2001-03-30
WO1993006103A1 (en) 1993-04-01
FI941287A0 (fi) 1994-03-18
TW210341B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-08-01
IL103160A0 (en) 1993-02-21
AU2660092A (en) 1993-04-27
NZ244398A (en) 1995-02-24
EP0633885A1 (en) 1995-01-18
JPH07501791A (ja) 1995-02-23
IL103160A (en) 1999-08-17
US5504085A (en) 1996-04-02
DK162491D0 (da) 1991-09-20
NO940989L (no) 1994-03-18
NO940989D0 (no) 1994-03-18
FI941287L (fi) 1994-03-18

Similar Documents

Publication Publication Date Title
AU663523B2 (en) Triazoloquinoxalin-1,4-diones and their preparation and use
AU624885B2 (en) Substituted fused quinoxaline -2,3 (1h,4h) diones, their preparation and use
IE66561B1 (en) Quinoxaline compounds and their preparation and use
US5559106A (en) Heterocyclic compounds, their use and preparation
EP0698024B1 (en) [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE
AU692524B2 (en) Imidazol {1, 2-9} quinoxalinone derivatives and the preparation and use
EP0783504B1 (en) [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE AS ANTAGONISTS OF AMPA-RECEPTORS
EP0511152A2 (en) Quinoxaline compounds, their preparation and use
EP0781282B1 (en) [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired