AU644533B2 - An acetohydroxamic acid compound, pharmaceutical compositions containing this compound and processes for the preparation of this compound and these compositions - Google Patents
An acetohydroxamic acid compound, pharmaceutical compositions containing this compound and processes for the preparation of this compound and these compositionsInfo
- Publication number
- AU644533B2 AU644533B2 AU20360/92A AU2036092A AU644533B2 AU 644533 B2 AU644533 B2 AU 644533B2 AU 20360/92 A AU20360/92 A AU 20360/92A AU 2036092 A AU2036092 A AU 2036092A AU 644533 B2 AU644533 B2 AU 644533B2
- Authority
- AU
- Australia
- Prior art keywords
- compound
- acetohydroxamic acid
- pharmaceutical compositions
- processes
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 229960001171 acetohydroxamic acid Drugs 0.000 title abstract 3
- -1 acetohydroxamic acid compound Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 2
- 239000000203 mixture Substances 0.000 title 1
- 150000002923 oximes Chemical class 0.000 abstract 2
- RBIGKSZIQCTIJF-UHFFFAOYSA-N 3-formylthiophene Chemical compound O=CC=1C=CSC=1 RBIGKSZIQCTIJF-UHFFFAOYSA-N 0.000 abstract 1
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 abstract 1
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 abstract 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 239000001116 FEMA 4028 Substances 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 abstract 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 abstract 1
- 229960004853 betadex Drugs 0.000 abstract 1
- 229910052796 boron Inorganic materials 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- HHKRHJJLCBYPSJ-UHFFFAOYSA-N n-(thiophen-3-ylmethyl)hydroxylamine Chemical compound ONCC=1C=CSC=1 HHKRHJJLCBYPSJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4123613 | 1991-07-17 | ||
| DE4123613A DE4123613C1 (enExample) | 1991-07-17 | 1991-07-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2036092A AU2036092A (en) | 1993-01-28 |
| AU644533B2 true AU644533B2 (en) | 1993-12-09 |
Family
ID=6436313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU20360/92A Ceased AU644533B2 (en) | 1991-07-17 | 1992-07-16 | An acetohydroxamic acid compound, pharmaceutical compositions containing this compound and processes for the preparation of this compound and these compositions |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5252562A (enExample) |
| EP (1) | EP0523499B1 (enExample) |
| AT (1) | ATE120460T1 (enExample) |
| AU (1) | AU644533B2 (enExample) |
| CA (1) | CA2070492A1 (enExample) |
| DE (2) | DE4123613C1 (enExample) |
| DK (1) | DK0523499T3 (enExample) |
| ES (1) | ES2073214T3 (enExample) |
| GR (1) | GR3015673T3 (enExample) |
| HK (1) | HK1005189A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1954320A2 (en) * | 2005-11-15 | 2008-08-13 | Baxter International Inc. | Compositions comprising lipoxygenase inhibitors and cyclodextrin |
| EP4008327A1 (en) | 2009-04-29 | 2022-06-08 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0196184B1 (en) * | 1985-03-16 | 1992-09-16 | The Wellcome Foundation Limited | Aryl derivatives |
| IE59397B1 (en) * | 1985-03-16 | 1994-02-23 | Wellcome Found | New aryl derivatives |
| GB8531839D0 (en) * | 1985-12-30 | 1986-02-05 | Wellcome Found | Aryl derivatives |
| GB8531838D0 (en) * | 1985-12-30 | 1986-02-05 | Wellcome Found | Aryl derivatives |
| US5036157A (en) * | 1986-03-11 | 1991-07-30 | Burroughs Wellcome Co. | Aryl derivatives |
| US5026729A (en) * | 1987-02-10 | 1991-06-25 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
| CA1316935C (en) * | 1987-12-09 | 1993-04-27 | Hiromitsu Saito | Hydroxamic acid derivatives |
| EP0351214A1 (en) * | 1988-07-14 | 1990-01-17 | The Wellcome Foundation Limited | Anti-inflammatory aryl derivatives |
| EP0412939A3 (en) * | 1989-08-11 | 1991-09-04 | Ciba-Geigy Ag | Certain benzopyran and benzothiopyran derivatives |
| FR2660309B1 (fr) * | 1990-03-27 | 1992-07-17 | Roussel Uclaf | Nouveaux complexes de l'acide tiaprofenique ou de ses esters insolubles ou partiellement solubles avec les cyclodextrines ou leurs derives. |
-
1991
- 1991-07-17 DE DE4123613A patent/DE4123613C1/de not_active Expired - Fee Related
-
1992
- 1992-06-04 CA CA002070492A patent/CA2070492A1/en not_active Abandoned
- 1992-07-06 DE DE59201764T patent/DE59201764D1/de not_active Expired - Lifetime
- 1992-07-06 DK DK92111427.8T patent/DK0523499T3/da active
- 1992-07-06 EP EP92111427A patent/EP0523499B1/de not_active Expired - Lifetime
- 1992-07-06 ES ES92111427T patent/ES2073214T3/es not_active Expired - Lifetime
- 1992-07-06 AT AT92111427T patent/ATE120460T1/de not_active IP Right Cessation
- 1992-07-10 US US07/911,623 patent/US5252562A/en not_active Expired - Lifetime
- 1992-07-16 AU AU20360/92A patent/AU644533B2/en not_active Ceased
-
1995
- 1995-04-03 GR GR950400817T patent/GR3015673T3/el unknown
-
1998
- 1998-05-19 HK HK98104298A patent/HK1005189A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3015673T3 (en) | 1995-07-31 |
| CA2070492A1 (en) | 1993-01-18 |
| ATE120460T1 (de) | 1995-04-15 |
| US5252562A (en) | 1993-10-12 |
| DE59201764D1 (de) | 1995-05-04 |
| EP0523499B1 (de) | 1995-03-29 |
| ES2073214T3 (es) | 1995-08-01 |
| DE4123613C1 (enExample) | 1993-02-04 |
| DK0523499T3 (da) | 1995-06-12 |
| HK1005189A1 (en) | 1998-12-24 |
| AU2036092A (en) | 1993-01-28 |
| EP0523499A1 (de) | 1993-01-20 |
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