AU640486B2 - Hypotriglyceridemic use of certain bis(3,5-di-alkyl-4-hydroxyphenylthio) methanes - Google Patents

Hypotriglyceridemic use of certain bis(3,5-di-alkyl-4-hydroxyphenylthio) methanes

Info

Publication number
AU640486B2
AU640486B2 AU78365/91A AU7836591A AU640486B2 AU 640486 B2 AU640486 B2 AU 640486B2 AU 78365/91 A AU78365/91 A AU 78365/91A AU 7836591 A AU7836591 A AU 7836591A AU 640486 B2 AU640486 B2 AU 640486B2
Authority
AU
Australia
Prior art keywords
patient
compound
hydroxyphenylthio
hypertriglyceridemia
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU78365/91A
Other languages
English (en)
Other versions
AU7836591A (en
Inventor
Richard L. Jackson
George Ku
Simon J.T. Mao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of AU7836591A publication Critical patent/AU7836591A/en
Application granted granted Critical
Publication of AU640486B2 publication Critical patent/AU640486B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU78365/91A 1990-06-19 1991-06-14 Hypotriglyceridemic use of certain bis(3,5-di-alkyl-4-hydroxyphenylthio) methanes Ceased AU640486B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/540,657 US5122542A (en) 1990-06-19 1990-06-19 Hypotriglyceridemic use of certain bis (3,5-di-alkyl-4-hydroxyphenylthio)methanes
US540657 2000-03-31

Publications (2)

Publication Number Publication Date
AU7836591A AU7836591A (en) 1992-01-02
AU640486B2 true AU640486B2 (en) 1993-08-26

Family

ID=24156398

Family Applications (1)

Application Number Title Priority Date Filing Date
AU78365/91A Ceased AU640486B2 (en) 1990-06-19 1991-06-14 Hypotriglyceridemic use of certain bis(3,5-di-alkyl-4-hydroxyphenylthio) methanes

Country Status (13)

Country Link
US (1) US5122542A (enExample)
EP (1) EP0462556B1 (enExample)
JP (1) JPH04230213A (enExample)
KR (1) KR0168649B1 (enExample)
AT (1) ATE129151T1 (enExample)
AU (1) AU640486B2 (enExample)
DE (1) DE69113871T2 (enExample)
DK (1) DK0462556T3 (enExample)
ES (1) ES2080854T3 (enExample)
GR (1) GR3018351T3 (enExample)
IE (1) IE69315B1 (enExample)
TW (1) TW205542B (enExample)
ZA (1) ZA914538B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100004333A1 (en) * 2004-12-17 2010-01-07 Stocker Roland O Compositions and methods for treating cardiovascular disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734527A (en) * 1986-10-17 1988-03-29 Merrell Dow Pharmaceuticals Inc. Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol
US4900757A (en) * 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
US4954528A (en) * 1988-12-08 1990-09-04 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic use of bis(3,5-di-tertiary-butly-4-hydroxyphenylthio)methane
US4959392A (en) * 1989-07-24 1990-09-25 Merrell Dow Pharmaceuticals Inc. Method of treating diabetes mellitus

Also Published As

Publication number Publication date
IE69315B1 (en) 1996-09-04
AU7836591A (en) 1992-01-02
EP0462556A3 (en) 1992-03-11
TW205542B (enExample) 1993-05-11
GR3018351T3 (en) 1996-03-31
KR920000327A (ko) 1992-01-29
DE69113871T2 (de) 1996-04-04
KR0168649B1 (ko) 1999-01-15
JPH04230213A (ja) 1992-08-19
EP0462556A2 (en) 1991-12-27
EP0462556B1 (en) 1995-10-18
ZA914538B (en) 1992-03-25
US5122542A (en) 1992-06-16
DK0462556T3 (da) 1995-11-27
ATE129151T1 (de) 1995-11-15
ES2080854T3 (es) 1996-02-16
IE912087A1 (en) 1992-01-01
DE69113871D1 (de) 1995-11-23

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired