AU633207B2 - Compositions comprising cytotoxic agent and permeation enhancers - Google Patents

Compositions comprising cytotoxic agent and permeation enhancers Download PDF

Info

Publication number
AU633207B2
AU633207B2 AU75620/91A AU7562091A AU633207B2 AU 633207 B2 AU633207 B2 AU 633207B2 AU 75620/91 A AU75620/91 A AU 75620/91A AU 7562091 A AU7562091 A AU 7562091A AU 633207 B2 AU633207 B2 AU 633207B2
Authority
AU
Australia
Prior art keywords
permeation
weight
composition
cytotoxic agent
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU75620/91A
Other languages
English (en)
Other versions
AU7562091A (en
Inventor
Michel J.N. Cormier
Lina T Taskovich
Su Il Yum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AU7562091A publication Critical patent/AU7562091A/en
Application granted granted Critical
Publication of AU633207B2 publication Critical patent/AU633207B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU75620/91A 1990-03-30 1991-03-25 Compositions comprising cytotoxic agent and permeation enhancers Ceased AU633207B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50248890A 1990-03-30 1990-03-30
US502488 1990-03-30

Publications (2)

Publication Number Publication Date
AU7562091A AU7562091A (en) 1991-10-30
AU633207B2 true AU633207B2 (en) 1993-01-21

Family

ID=23998069

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75620/91A Ceased AU633207B2 (en) 1990-03-30 1991-03-25 Compositions comprising cytotoxic agent and permeation enhancers

Country Status (9)

Country Link
EP (1) EP0522006A1 (ja)
JP (1) JPH05505807A (ja)
AU (1) AU633207B2 (ja)
CA (1) CA2038969A1 (ja)
FI (1) FI924344A0 (ja)
IE (1) IE910976A1 (ja)
PT (1) PT97139A (ja)
WO (1) WO1991015210A1 (ja)
ZA (1) ZA912228B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU722285B2 (en) * 1996-06-19 2000-07-27 Novartis Ag Cyclosporin-containing soft capsule preparations
ES2227700T3 (es) * 1996-06-19 2005-04-01 Novartis Ag Preparados de capsulas blandas que contienen ciclosporina.
US5958876A (en) * 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions
AU753018B2 (en) * 1996-06-19 2002-10-03 Novartis Ag Cyclosporin-containing soft capsule preparations
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
NZ314702A (en) * 1997-04-29 1998-07-28 Bernard Charles Sherman Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent
WO2005079855A1 (es) * 2004-02-23 2005-09-01 David Quintanar Guerrero Composicion promotora de penetracion a base de esteres de acidos grasos de sacarosa
KR20220047347A (ko) 2019-08-14 2022-04-15 나노메틱스 엘엘씨 (디.피.에이 피에이치디 바이오사이언시스) 우라실 피부 약학 제형

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37447B1 (en) * 1972-04-05 1977-07-20 Procter & Gamble Dermatological compositions
US4865848A (en) * 1987-02-26 1989-09-12 Alza Corporation Skin permeation enhancer compositions using sucrose esters
US4849426A (en) * 1987-05-15 1989-07-18 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents

Also Published As

Publication number Publication date
PT97139A (pt) 1991-11-29
IE910976A1 (en) 1991-10-09
CA2038969A1 (en) 1991-10-01
ZA912228B (en) 1991-12-24
JPH05505807A (ja) 1993-08-26
AU7562091A (en) 1991-10-30
WO1991015210A1 (en) 1991-10-17
EP0522006A1 (en) 1993-01-13
FI924344A (fi) 1992-09-28
FI924344A0 (fi) 1992-09-28

Similar Documents

Publication Publication Date Title
CA2309688C (en) Penetration enhancing and irritation reducing systems
EP0069385B1 (en) Use of eucalyptol for enhancing skin permeation of bioaffecting agents
CA2135925C (en) Use of glycerin in moderating transdermal drug delivery
US5093133A (en) Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
US4560553A (en) Use of eucalyptol for enhancing skin permeation of bio-affecting agents
CA2170016C (en) Improved method for treating hair loss
HU197847B (en) Process for producing therapeutical preparations suitable for transdermatic treating
EP0651993B1 (en) Percutaneously administrable base composition and drug composition prepared therefrom
AU633207B2 (en) Compositions comprising cytotoxic agent and permeation enhancers
JPH08175986A (ja) 経皮活性を示す5−アミノレブリン酸含有薬学組成物
CA1176167A (en) Use of n,n-diethyl-m-toluamide for enhancing skin permeation of bio-affecting agents
US4762851A (en) Pyroglutamic acid esters used as dermal penetration enhancers for drugs
EP2910254A1 (en) Base and external preparation for skin
US4888360A (en) Carvone enhancement of transdermal drug delivery
US4888362A (en) Eugenol enhancement of transdermal drug delivery
EP1043979B1 (en) Compositions for the transdermal and dermal administration of biologically active agents
US5183665A (en) Composition for percutaneous administration and method for enhancing percutaneous absorption of a physiologically active ingredient empolying the same
NZ196395A (en) Topical pharmaceutical composition containing n,n-diethyl-m-toluamide
MXPA00004513A (en) Penetration enhancing and irritation reducing systems