AU633207B2 - Compositions comprising cytotoxic agent and permeation enhancers - Google Patents

Compositions comprising cytotoxic agent and permeation enhancers Download PDF

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Publication number
AU633207B2
AU633207B2 AU75620/91A AU7562091A AU633207B2 AU 633207 B2 AU633207 B2 AU 633207B2 AU 75620/91 A AU75620/91 A AU 75620/91A AU 7562091 A AU7562091 A AU 7562091A AU 633207 B2 AU633207 B2 AU 633207B2
Authority
AU
Australia
Prior art keywords
permeation
weight
composition
cytotoxic agent
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU75620/91A
Other languages
English (en)
Other versions
AU7562091A (en
Inventor
Michel J.N. Cormier
Lina T Taskovich
Su Il Yum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AU7562091A publication Critical patent/AU7562091A/en
Application granted granted Critical
Publication of AU633207B2 publication Critical patent/AU633207B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU75620/91A 1990-03-30 1991-03-25 Compositions comprising cytotoxic agent and permeation enhancers Ceased AU633207B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50248890A 1990-03-30 1990-03-30
US502488 1990-03-30

Publications (2)

Publication Number Publication Date
AU7562091A AU7562091A (en) 1991-10-30
AU633207B2 true AU633207B2 (en) 1993-01-21

Family

ID=23998069

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75620/91A Ceased AU633207B2 (en) 1990-03-30 1991-03-25 Compositions comprising cytotoxic agent and permeation enhancers

Country Status (9)

Country Link
EP (1) EP0522006A1 (fr)
JP (1) JPH05505807A (fr)
AU (1) AU633207B2 (fr)
CA (1) CA2038969A1 (fr)
FI (1) FI924344A (fr)
IE (1) IE910976A1 (fr)
PT (1) PT97139A (fr)
WO (1) WO1991015210A1 (fr)
ZA (1) ZA912228B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283361B6 (sk) * 1996-06-19 2003-06-03 Novartis Ag Prípravok vo forme mäkkej kapsuly obsahujúci cyklosporín
AU722285B2 (en) * 1996-06-19 2000-07-27 Novartis Ag Cyclosporin-containing soft capsule preparations
AU753018B2 (en) * 1996-06-19 2002-10-03 Novartis Ag Cyclosporin-containing soft capsule preparations
US5958876A (en) * 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
NZ314702A (en) * 1997-04-29 1998-07-28 Bernard Charles Sherman Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent
WO2005079855A1 (fr) * 2004-02-23 2005-09-01 David Quintanar Guerrero Composition activatrice de penetration a base d'esters d'acides gras de saccharose
EP4013418A4 (fr) * 2019-08-14 2023-07-19 Nanometics LLC (D.B.A. Phd Biosciences) Formulation pharmaceutique dermique d'uracile

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37447B1 (en) * 1972-04-05 1977-07-20 Procter & Gamble Dermatological compositions
US4865848A (en) * 1987-02-26 1989-09-12 Alza Corporation Skin permeation enhancer compositions using sucrose esters
US4849426A (en) * 1987-05-15 1989-07-18 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents

Also Published As

Publication number Publication date
FI924344A0 (fi) 1992-09-28
CA2038969A1 (fr) 1991-10-01
WO1991015210A1 (fr) 1991-10-17
JPH05505807A (ja) 1993-08-26
PT97139A (pt) 1991-11-29
IE910976A1 (en) 1991-10-09
EP0522006A1 (fr) 1993-01-13
ZA912228B (en) 1991-12-24
FI924344A (fi) 1992-09-28
AU7562091A (en) 1991-10-30

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