AU627489B2 - The use of transglutaminases as immunosuppressants - Google Patents
The use of transglutaminases as immunosuppressants Download PDFInfo
- Publication number
- AU627489B2 AU627489B2 AU40904/89A AU4090489A AU627489B2 AU 627489 B2 AU627489 B2 AU 627489B2 AU 40904/89 A AU40904/89 A AU 40904/89A AU 4090489 A AU4090489 A AU 4090489A AU 627489 B2 AU627489 B2 AU 627489B2
- Authority
- AU
- Australia
- Prior art keywords
- transglutaminase
- patient
- administering
- effective amount
- xiii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3829524 | 1988-08-31 | ||
DE3829524A DE3829524A1 (de) | 1988-08-31 | 1988-08-31 | Verwendung von transglutaminasen als immunsuppressiva |
Publications (2)
Publication Number | Publication Date |
---|---|
AU4090489A AU4090489A (en) | 1990-03-08 |
AU627489B2 true AU627489B2 (en) | 1992-08-27 |
Family
ID=6361974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU40904/89A Expired AU627489B2 (en) | 1988-08-31 | 1989-08-30 | The use of transglutaminases as immunosuppressants |
Country Status (11)
Country | Link |
---|---|
US (2) | US5464615A (da) |
EP (1) | EP0358995B1 (da) |
JP (1) | JP2831045B2 (da) |
KR (1) | KR0154523B1 (da) |
AT (1) | ATE94762T1 (da) |
AU (1) | AU627489B2 (da) |
CA (1) | CA1338776C (da) |
DE (2) | DE3829524A1 (da) |
DK (1) | DK174512B1 (da) |
ES (1) | ES2059658T3 (da) |
PT (1) | PT91583B (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3829524A1 (de) * | 1988-08-31 | 1990-03-01 | Behringwerke Ag | Verwendung von transglutaminasen als immunsuppressiva |
DE3829523A1 (de) * | 1988-08-31 | 1990-03-01 | Behringwerke Ag | Verwendung von plasminogen-aktivator-inhibitor (pai-2) zur immunsuppression |
JPH03240738A (ja) * | 1990-02-20 | 1991-10-28 | Hoechst Japan Ltd | 糖尿病性壊疽治療剤 |
JP3550685B2 (ja) * | 1992-04-21 | 2004-08-04 | 味の素株式会社 | 創傷治療剤 |
ATE184199T1 (de) * | 1992-11-12 | 1999-09-15 | Zymogenetics Inc | Verwendung von lokal appliziertem faktor xiii zur verhinderung von blutungen |
KR100302935B1 (ko) * | 1993-03-30 | 2001-11-30 | 바트 루디거 | 사람혈액응고인자xiii과아프로티닌을포함하는약제학적조성물 |
DE19630557C2 (de) * | 1996-07-18 | 1998-07-02 | Schuppan Detlef Priv Doz Dr Dr | Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie |
AU7483798A (en) * | 1997-05-14 | 1998-12-08 | Zymogenetics Inc. | Use of factor xiii for the manufacture of a medicament for the treatment of reperfusion injury and mucosal damage |
EP1201136A1 (en) * | 2000-10-31 | 2002-05-02 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Food grade transglutaminase inhibitor and uses thereof |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
EP1889198B1 (en) | 2005-04-28 | 2014-11-26 | Proteus Digital Health, Inc. | Pharma-informatics system |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
WO2017009136A1 (en) | 2015-07-15 | 2017-01-19 | Novo Nordisk Health Care Ag | Factor xiii for the treatment of interstitial cystitis |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4536387A (en) * | 1982-02-12 | 1985-08-20 | Unitika Ltd. | Anti-cancer device |
AU1138388A (en) * | 1987-02-09 | 1988-08-11 | Mycogen Plant Science, Inc. | Hybrid rna virus |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT359652B (de) * | 1979-02-15 | 1980-11-25 | Immuno Ag | Verfahren zur herstellung eines gewebekleb- stoffes |
JPS56135418A (en) * | 1980-03-27 | 1981-10-22 | Green Cross Corp:The | Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human |
US4923807A (en) * | 1984-05-18 | 1990-05-08 | New England Medical Center Hospitals Inc. | Arg-Serpin human plasminogen activator inhibitor designated PAI-2 |
JPS63196520A (ja) * | 1987-02-09 | 1988-08-15 | Hoechst Japan Kk | 潰瘍性大腸炎治療剤 |
US5013719A (en) * | 1988-05-13 | 1991-05-07 | Merrell Dow Pharmaceuticals Inc. | Method of effecting immunosuppression |
DE3829524A1 (de) * | 1988-08-31 | 1990-03-01 | Behringwerke Ag | Verwendung von transglutaminasen als immunsuppressiva |
-
1988
- 1988-08-31 DE DE3829524A patent/DE3829524A1/de not_active Withdrawn
-
1989
- 1989-08-24 ES ES89115614T patent/ES2059658T3/es not_active Expired - Lifetime
- 1989-08-24 AT AT89115614T patent/ATE94762T1/de not_active IP Right Cessation
- 1989-08-24 EP EP89115614A patent/EP0358995B1/de not_active Expired - Lifetime
- 1989-08-24 DE DE89115614T patent/DE58905671D1/de not_active Expired - Lifetime
- 1989-08-30 AU AU40904/89A patent/AU627489B2/en not_active Expired
- 1989-08-30 JP JP1221876A patent/JP2831045B2/ja not_active Expired - Lifetime
- 1989-08-30 DK DK198904279A patent/DK174512B1/da not_active IP Right Cessation
- 1989-08-30 PT PT91583A patent/PT91583B/pt not_active IP Right Cessation
- 1989-08-30 CA CA000609835A patent/CA1338776C/en not_active Expired - Fee Related
- 1989-08-30 KR KR1019890012384A patent/KR0154523B1/ko not_active IP Right Cessation
-
1994
- 1994-09-22 US US08/310,038 patent/US5464615A/en not_active Expired - Lifetime
-
1995
- 1995-06-06 US US08/468,058 patent/US5695753A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4536387A (en) * | 1982-02-12 | 1985-08-20 | Unitika Ltd. | Anti-cancer device |
AU1138388A (en) * | 1987-02-09 | 1988-08-11 | Mycogen Plant Science, Inc. | Hybrid rna virus |
Also Published As
Publication number | Publication date |
---|---|
DE58905671D1 (de) | 1993-10-28 |
JPH02108631A (ja) | 1990-04-20 |
DK427989D0 (da) | 1989-08-30 |
US5464615A (en) | 1995-11-07 |
DK427989A (da) | 1990-03-01 |
AU4090489A (en) | 1990-03-08 |
EP0358995B1 (de) | 1993-09-22 |
EP0358995A3 (en) | 1990-08-16 |
PT91583A (pt) | 1990-03-30 |
EP0358995A2 (de) | 1990-03-21 |
ES2059658T3 (es) | 1994-11-16 |
PT91583B (pt) | 1995-05-31 |
DE3829524A1 (de) | 1990-03-01 |
ATE94762T1 (de) | 1993-10-15 |
US5695753A (en) | 1997-12-09 |
KR900002802A (ko) | 1990-03-23 |
DK174512B1 (da) | 2003-05-05 |
KR0154523B1 (ko) | 1998-11-16 |
CA1338776C (en) | 1996-12-10 |
JP2831045B2 (ja) | 1998-12-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HB | Alteration of name in register |
Owner name: AVENTIS BEHRING GMBH Free format text: FORMER NAME WAS: CENTEON PHARMA GMBH |