AU618794B2 - 7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo- propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugs - Google Patents

7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo- propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugs Download PDF

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Publication number
AU618794B2
AU618794B2 AU32263/89A AU3226389A AU618794B2 AU 618794 B2 AU618794 B2 AU 618794B2 AU 32263/89 A AU32263/89 A AU 32263/89A AU 3226389 A AU3226389 A AU 3226389A AU 618794 B2 AU618794 B2 AU 618794B2
Authority
AU
Australia
Prior art keywords
formula
dihydro
preparation
compound
difluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU32263/89A
Other languages
English (en)
Other versions
AU3226389A (en
Inventor
Jordi Frigola Constansa
Juan Pares Corominas
Augusto Colombo Pinol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of AU3226389A publication Critical patent/AU3226389A/en
Application granted granted Critical
Publication of AU618794B2 publication Critical patent/AU618794B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU32263/89A 1988-03-31 1989-03-31 7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo- propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugs Ceased AU618794B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8804289A FR2629456B1 (fr) 1988-03-31 1988-03-31 Derives des acides 7-(1-imidazolyl),1,4-dihydro-4-oxo-6,8-difluoro-1-cyclopropyl-3-quinoleincarboxylique, leur preparation et leur application en tant que medicaments
FR8804289 1988-03-31

Publications (2)

Publication Number Publication Date
AU3226389A AU3226389A (en) 1989-10-05
AU618794B2 true AU618794B2 (en) 1992-01-09

Family

ID=9364848

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32263/89A Ceased AU618794B2 (en) 1988-03-31 1989-03-31 7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo- propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugs

Country Status (10)

Country Link
US (1) US5098913A (OSRAM)
EP (1) EP0340055B1 (OSRAM)
AT (1) ATE86620T1 (OSRAM)
AU (1) AU618794B2 (OSRAM)
DE (1) DE68905222T2 (OSRAM)
ES (1) ES2010471A6 (OSRAM)
FR (1) FR2629456B1 (OSRAM)
GR (1) GR3007320T3 (OSRAM)
NZ (1) NZ228515A (OSRAM)
ZA (1) ZA892312B (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2002864C (en) * 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530930A (en) * 1982-12-29 1985-07-23 Kanebo, Ltd. Antimicrobial 1-ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives
EP0203488A2 (de) * 1985-05-30 1986-12-03 Bayer Ag 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolin-carbonsäuren und -1,8-napthyridin-3-carbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574404B1 (fr) * 1984-12-12 1987-04-24 Provesan Sa Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530930A (en) * 1982-12-29 1985-07-23 Kanebo, Ltd. Antimicrobial 1-ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives
EP0203488A2 (de) * 1985-05-30 1986-12-03 Bayer Ag 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolin-carbonsäuren und -1,8-napthyridin-3-carbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel

Also Published As

Publication number Publication date
DE68905222T2 (de) 1993-06-17
ES2010471A6 (es) 1989-11-01
US5098913A (en) 1992-03-24
DE68905222D1 (de) 1993-04-15
ZA892312B (en) 1989-12-27
AU3226389A (en) 1989-10-05
FR2629456B1 (fr) 1991-07-05
NZ228515A (en) 1990-10-26
EP0340055B1 (fr) 1993-03-10
FR2629456A1 (fr) 1989-10-06
ATE86620T1 (de) 1993-03-15
EP0340055A1 (fr) 1989-11-02
GR3007320T3 (OSRAM) 1993-07-30

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