AU606692B2 - Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds - Google Patents

Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds Download PDF

Info

Publication number
AU606692B2
AU606692B2 AU18241/88A AU1824188A AU606692B2 AU 606692 B2 AU606692 B2 AU 606692B2 AU 18241/88 A AU18241/88 A AU 18241/88A AU 1824188 A AU1824188 A AU 1824188A AU 606692 B2 AU606692 B2 AU 606692B2
Authority
AU
Australia
Prior art keywords
phenyl
hydroxy
group
compounds
propanone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU18241/88A
Other languages
English (en)
Other versions
AU1824188A (en
Inventor
Gerd Petrick
Klemens Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helopharm W Petrik and Co KG
Original Assignee
HELOPHARM PETRIK CO KG
Helopharm W Petrik and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HELOPHARM PETRIK CO KG, Helopharm W Petrik and Co KG filed Critical HELOPHARM PETRIK CO KG
Publication of AU1824188A publication Critical patent/AU1824188A/en
Application granted granted Critical
Publication of AU606692B2 publication Critical patent/AU606692B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
AU18241/88A 1987-06-23 1988-06-22 Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds Ceased AU606692B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87109015A EP0296264A1 (de) 1987-06-23 1987-06-23 Aminopropanolderivate von 3-(2-Hydroxyphenyl)-1-propanonderivaten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP87109015 1987-06-23

Publications (2)

Publication Number Publication Date
AU1824188A AU1824188A (en) 1989-01-05
AU606692B2 true AU606692B2 (en) 1991-02-14

Family

ID=8197084

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18241/88A Ceased AU606692B2 (en) 1987-06-23 1988-06-22 Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds

Country Status (17)

Country Link
EP (1) EP0296264A1 (it)
JP (1) JPS6426540A (it)
KR (1) KR890000400A (it)
AU (1) AU606692B2 (it)
DD (1) DD271701A5 (it)
DE (2) DE3868357D1 (it)
DK (1) DK342188A (it)
ES (1) ES2019857T3 (it)
FI (1) FI883002A (it)
GR (2) GR890300035T1 (it)
HU (1) HU204503B (it)
IL (1) IL86812A (it)
NO (1) NO167974C (it)
PT (1) PT87792B (it)
SU (1) SU1628855A3 (it)
YU (1) YU119988A (it)
ZA (1) ZA884436B (it)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362115A1 (fr) * 1976-08-21 1978-03-17 Hexachimie Nouveaux aryloxy-1 amino-3 propanols-2, leur preparation et leur utilisation, notamment en therapeutique
US4540697A (en) * 1982-09-09 1985-09-10 Basf Aktiengesellschaft Aminopropanol derivatives of 2-hydroxy-β-phenyl-propiophenones, pharmaceutical compositions and use
AU1259488A (en) * 1987-03-26 1988-09-29 Helopharm W. Petrik Gmbh & Co. Kg Process for the preparation of 5-hydroxydiprafenone and its acid addition salts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226863A1 (de) * 1981-09-18 1983-04-07 Basf Ag, 6700 Ludwigshafen Aminopropanolderivate von 2-hydroxy-ss-phenyl-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362115A1 (fr) * 1976-08-21 1978-03-17 Hexachimie Nouveaux aryloxy-1 amino-3 propanols-2, leur preparation et leur utilisation, notamment en therapeutique
US4540697A (en) * 1982-09-09 1985-09-10 Basf Aktiengesellschaft Aminopropanol derivatives of 2-hydroxy-β-phenyl-propiophenones, pharmaceutical compositions and use
AU1259488A (en) * 1987-03-26 1988-09-29 Helopharm W. Petrik Gmbh & Co. Kg Process for the preparation of 5-hydroxydiprafenone and its acid addition salts

Also Published As

Publication number Publication date
GR890300035T1 (en) 1989-04-12
GR3004456T3 (it) 1993-03-31
ES2019857T3 (es) 1993-09-16
DK342188A (da) 1988-12-24
ES2019857A4 (es) 1991-07-16
NO167974B (no) 1991-09-23
SU1628855A3 (ru) 1991-02-15
YU119988A (en) 1989-12-31
JPS6426540A (en) 1989-01-27
DE3821259A1 (de) 1989-01-05
FI883002A (fi) 1988-12-24
IL86812A0 (en) 1988-11-30
DD271701A5 (de) 1989-09-13
FI883002A0 (fi) 1988-06-22
ZA884436B (en) 1989-03-29
HU204503B (en) 1992-01-28
DE3868357D1 (de) 1992-03-26
NO882770L (no) 1988-12-27
AU1824188A (en) 1989-01-05
JPH0320382B2 (it) 1991-03-19
DK342188D0 (da) 1988-06-22
PT87792A (pt) 1988-07-01
IL86812A (en) 1991-12-15
NO167974C (no) 1992-01-02
PT87792B (pt) 1992-10-30
EP0296264A1 (de) 1988-12-28
NO882770D0 (no) 1988-06-22
HUT51234A (en) 1990-04-28
KR890000400A (ko) 1989-03-14

Similar Documents

Publication Publication Date Title
US3941789A (en) N-Aryl-N'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof
EP0159566A1 (en) Novel piperazine derivatives, processes for production thereof, and pharmaceutical compositions comprising said compounds as active ingredient
US4730042A (en) Compounds 1 or 3-hydroxy-4-benzyl-6-methyl-7-(4-isopropylamino-butoxy)-1,3-dihydro[3,4-C]pyridine and 2-methyl-3-(4-isopropyl-aminobutoxy)-4-(1'-morphilinomethyl)-5-hydroxymethyl-6-benzyl pyridine, useful for treating cardiac arrhythmias
US4460605A (en) 2-[2'-Hydroxy-3'-(1,1-dimethylpropylamino)-propoxy]-β-phenylpropiophenone, its physiologically acceptable acid addition salts, and pharmaceutical compositions
AU606692B2 (en) Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds
US3706755A (en) Certain 4(3-(4-(phenyl)-3,6-dihydro-1(2h)pyridyl)-2 - hydroxy-propoxy)-benzophenones
US3959338A (en) 1-(Cyano-phenoxy)-2-hydroxy-3-hydroxyalkylamino-propanes and salts thereof
CA1331877C (en) Aminopropanol derivatives of 3-(3-hydroxyphenyl)-1- propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds
US3822266A (en) (3-(1-piperazinyl)-2-hydroxy-propoxy)acetanilides
US5118685A (en) Aminopropanol derivatives of substituted 2-hydroxy-propiophenones, and therapeutic agents containing these compounds
US4048322A (en) Bronchially effective xanthene-9-carboxylates
US4000274A (en) Pharmaceutical compositions containing an n-aryl-n'-(phenyl-or-phenoxy-alkyl)-piperazine and method of use
US3954776A (en) 1-[Methylated piperidino(and pyrrolidin-1-yl)]-3-(substituted phenoxy)-2propanols
AU594840B2 (en) 1-aryloxy-3-amino-2-propanols
EP0352639B1 (de) p-Hydroxiphenon-Derivate und deren Anwendung
US4070461A (en) Biphenylyl ethers
IE49113B1 (en) Aminopropanol derivatives of 6-hydroxy-2,3,4,5-tetrahydro-1h-1-benzazepin-2-one,their preparation,and pharmaceutical formulations containing the said compounds
GB1583372A (en) 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives
IE41667B1 (en) Substituted phenylpiperazine compounds and pharmaceutical uses thereof
US4025646A (en) Pharmaceutical compositions containing a 1-(cyano-phenoxy)-2-hydroxy-3-hydroxyalkylamino-propane and method of use
US3890439A (en) Imidazolidinone derivatives in the treatment of emesis and psychosomatic disturbances
JPS63290852A (ja) 化合物
US4442120A (en) 1-Aryloxy-3-alkylamino-propan-2-ols
EP0296592B1 (de) Aminopropanolderivate von 3-(2-Hydroxyphenyl)-1-propanon-Verbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
WO1991009834A1 (de) o-HYDROXY-β-(1-NAPHTHYL)-PROPIOPHENONDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL