AU596108B2 - 1,4-benzodioxane derivatives - Google Patents

1,4-benzodioxane derivatives Download PDF

Info

Publication number
AU596108B2
AU596108B2 AU60424/86A AU6042486A AU596108B2 AU 596108 B2 AU596108 B2 AU 596108B2 AU 60424/86 A AU60424/86 A AU 60424/86A AU 6042486 A AU6042486 A AU 6042486A AU 596108 B2 AU596108 B2 AU 596108B2
Authority
AU
Australia
Prior art keywords
group
formula
integer
represented
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU60424/86A
Other languages
English (en)
Other versions
AU6042486A (en
Inventor
Hiroshi Katoh
Toshinobu Kunii
Norio Minami
Nobuyuki Mori
Fumihiro Ozaki
Mikio Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of AU6042486A publication Critical patent/AU6042486A/en
Application granted granted Critical
Publication of AU596108B2 publication Critical patent/AU596108B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU60424/86A 1985-07-23 1986-07-22 1,4-benzodioxane derivatives Ceased AU596108B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60161096A JPS6222777A (ja) 1985-07-23 1985-07-23 １，４−ベンゾジオキサン誘導体
JP60-161096 1985-07-23

Publications (2)

Publication Number Publication Date
AU6042486A AU6042486A (en) 1987-01-29
AU596108B2 true AU596108B2 (en) 1990-04-26

Family

ID=15728530

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60424/86A Ceased AU596108B2 (en) 1985-07-23 1986-07-22 1,4-benzodioxane derivatives

Country Status (13)

Country Link
US (2) US4794118A (enExample)
EP (2) EP0307970A1 (enExample)
JP (1) JPS6222777A (enExample)
KR (1) KR870001189A (enExample)
AT (1) ATE124692T1 (enExample)
AU (1) AU596108B2 (enExample)
CA (1) CA1277321C (enExample)
DE (1) DE3650347T2 (enExample)
DK (1) DK347486A (enExample)
ES (2) ES2004491A6 (enExample)
HU (1) HU203230B (enExample)
NZ (1) NZ216930A (enExample)
PH (1) PH23359A (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63179868A (ja) * 1987-01-21 1988-07-23 Eisai Co Ltd １，４−ベンゾジオキサン誘導体及びその製法
US5158956A (en) * 1990-05-04 1992-10-27 Eli Lilly And Company Method of inhibiting gastric acid secretion with benzodioxanes
JP2004525109A (ja) 2001-02-15 2004-08-19 キング・ファーマシューティカルズ・インコーポレイティッド 安定化された甲状腺ホルモン医薬組成物、及びその製法
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3101345A (en) * 1960-04-29 1963-08-20 Thomae Gmbh Dr K 2-hydroxymethyl-8-hydroxy-1,4-benzodioxane
US3166573A (en) * 1963-11-08 1965-01-19 Colgate Palmolive Co 2-(nitratoalkyl)-1, 4-benzodioxanes

Also Published As

Publication number Publication date
EP0307970A1 (en) 1989-03-22
US4959376A (en) 1990-09-25
NZ216930A (en) 1989-08-29
EP0210581A1 (en) 1987-02-04
JPS6222777A (ja) 1987-01-30
HUT44776A (en) 1988-04-28
ATE124692T1 (de) 1995-07-15
KR870001189A (ko) 1987-03-12
ES2006545A6 (es) 1989-05-01
EP0210581B1 (en) 1995-07-05
DK347486A (da) 1987-01-24
AU6042486A (en) 1987-01-29
HU203230B (en) 1991-06-28
PH23359A (en) 1989-07-14
CA1277321C (en) 1990-12-04
ES2004491A6 (es) 1989-01-16
JPH0535150B2 (enExample) 1993-05-25
DE3650347D1 (de) 1995-08-10
US4794118A (en) 1988-12-27
DE3650347T2 (de) 1996-01-25
DK347486D0 (da) 1986-07-22

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