AU584071B2 - 1a-hydroxyvitamin d2 analogs and process for preparing same - Google Patents

1a-hydroxyvitamin d2 analogs and process for preparing same

Info

Publication number
AU584071B2
AU584071B2 AU38895/85A AU3889585A AU584071B2 AU 584071 B2 AU584071 B2 AU 584071B2 AU 38895/85 A AU38895/85 A AU 38895/85A AU 3889585 A AU3889585 A AU 3889585A AU 584071 B2 AU584071 B2 AU 584071B2
Authority
AU
Australia
Prior art keywords
compound
compounds
vitamin
mixture
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU38895/85A
Other languages
English (en)
Other versions
AU3889585A (en
Inventor
Hector F. Deluca
Heinrich K. Schnoes
Rafal R. Sicinski
Yoko Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of AU3889585A publication Critical patent/AU3889585A/en
Application granted granted Critical
Publication of AU584071B2 publication Critical patent/AU584071B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU38895/85A 1984-03-05 1985-01-22 1a-hydroxyvitamin d2 analogs and process for preparing same Ceased AU584071B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58616084A 1984-03-05 1984-03-05
US586160 1984-03-05

Publications (2)

Publication Number Publication Date
AU3889585A AU3889585A (en) 1985-09-24
AU584071B2 true AU584071B2 (en) 1989-05-18

Family

ID=24344548

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38895/85A Ceased AU584071B2 (en) 1984-03-05 1985-01-22 1a-hydroxyvitamin d2 analogs and process for preparing same

Country Status (12)

Country Link
JP (1) JPH064536B2 (de)
AU (1) AU584071B2 (de)
BE (1) BE901879A (de)
CH (1) CH667658A5 (de)
DE (2) DE3590080C2 (de)
DK (1) DK153145C (de)
FR (1) FR2560597B1 (de)
GB (1) GB2155478B (de)
IE (1) IE57951B1 (de)
IL (1) IL74168A (de)
NL (1) NL8520021A (de)
WO (1) WO1985003939A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
IN171426B (de) * 1990-02-14 1992-10-10 Wisconsin Alumni Res Found

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
AU2593784A (en) * 1983-03-21 1984-09-27 F. Hoffmann-La Roche Ag Pharmaceutical ergocalciferols and intermediates
AU3837285A (en) * 1984-01-30 1985-08-09 Wisconsin Alumni Research Foundation 1a, 25-DIHYDROXY-22Z-DEHYDROVITAMIN D COMPOUND

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4206131A (en) * 1978-06-19 1980-06-03 The Upjohn Company Compounds and process
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
AU2593784A (en) * 1983-03-21 1984-09-27 F. Hoffmann-La Roche Ag Pharmaceutical ergocalciferols and intermediates
AU3837285A (en) * 1984-01-30 1985-08-09 Wisconsin Alumni Research Foundation 1a, 25-DIHYDROXY-22Z-DEHYDROVITAMIN D COMPOUND

Also Published As

Publication number Publication date
JPH064536B2 (ja) 1994-01-19
NL8520021A (nl) 1986-02-03
GB2155478B (en) 1987-12-16
DK153145C (da) 1988-10-31
DK506985A (da) 1985-11-06
IL74168A (en) 1988-11-15
WO1985003939A1 (en) 1985-09-12
GB8505486D0 (en) 1985-04-03
DK153145B (da) 1988-06-20
FR2560597B1 (fr) 1987-12-04
GB2155478A (en) 1985-09-25
CH667658A5 (de) 1988-10-31
BE901879A (fr) 1985-07-01
JPS61501447A (ja) 1986-07-17
DK506985D0 (da) 1985-11-04
DE3590080C2 (de) 1992-08-06
IE57951B1 (en) 1993-05-19
IL74168A0 (en) 1985-04-30
IE850520L (en) 1985-09-05
DE3590080T (de) 1986-02-20
FR2560597A1 (fr) 1985-09-06
AU3889585A (en) 1985-09-24

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