AU579593B2 - Novel peptides which are active on the central nervous system and have an action on the cholinergic system - Google Patents

Novel peptides which are active on the central nervous system and have an action on the cholinergic system

Info

Publication number
AU579593B2
AU579593B2 AU35394/84A AU3539484A AU579593B2 AU 579593 B2 AU579593 B2 AU 579593B2 AU 35394/84 A AU35394/84 A AU 35394/84A AU 3539484 A AU3539484 A AU 3539484A AU 579593 B2 AU579593 B2 AU 579593B2
Authority
AU
Australia
Prior art keywords
active
action
central nervous
novel peptides
cholinergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU35394/84A
Other languages
English (en)
Other versions
AU3539484A (en
Inventor
Rolf Geiger
Hermann Gerhards
Hansjorg Kruse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU3539484A publication Critical patent/AU3539484A/en
Application granted granted Critical
Publication of AU579593B2 publication Critical patent/AU579593B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • C07K14/6955—Corticotropin [ACTH] with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU35394/84A 1984-10-22 1984-11-13 Novel peptides which are active on the central nervous system and have an action on the cholinergic system Expired AU579593B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/663,193 US4623715A (en) 1984-10-22 1984-10-22 Novel peptides which are active on the central nervous system and have an action on the cholinergic system
US663193 1984-10-22

Publications (2)

Publication Number Publication Date
AU3539484A AU3539484A (en) 1986-05-01
AU579593B2 true AU579593B2 (en) 1988-12-01

Family

ID=24660834

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35394/84A Expired AU579593B2 (en) 1984-10-22 1984-11-13 Novel peptides which are active on the central nervous system and have an action on the cholinergic system

Country Status (13)

Country Link
US (2) US4623715A ( )
EP (1) EP0179332B1 ( )
JP (1) JPH075632B2 ( )
AT (1) ATE84544T1 ( )
AU (1) AU579593B2 ( )
CA (1) CA1267996A ( )
CS (1) CS408391A3 ( )
DE (1) DE3586979D1 ( )
DK (1) DK170649B1 ( )
ES (1) ES8703488A1 ( )
GR (1) GR852541B ( )
IE (1) IE59724B1 ( )
PT (1) PT81345B ( )

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565606A (en) * 1986-10-21 1996-10-15 Hoechst Aktiengesellschaft Synthesis of peptide aminoalkylamides and peptide hydrazides by the solid-phase method
ATE63821T1 (de) * 1987-08-14 1991-06-15 Akzo Nv Praeparat zur verhuetung oder bekaempfung von komplikationen bei diabetes.
US4945999A (en) * 1989-04-06 1990-08-07 The Charles Machine Works, Inc. Directional rod pusher
DE3931788A1 (de) * 1989-09-23 1991-04-04 Hoechst Ag Neue zns-aktive hexapeptide mit antiamnestischer wirkung
ZA914684B (en) * 1990-07-18 1992-04-29 Akzo Nv Use of a centrally acting acth analog in the manufacture of a medicament
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
US5190924A (en) * 1991-02-13 1993-03-02 Boc Health Care, Inc. Peptide amides and amide dimers useful as muscle relaxants
US7176279B2 (en) * 2000-06-28 2007-02-13 Palatin Technologies, Inc. Cyclic peptide compositions and methods for treatment of sexual dysfunction
US6579968B1 (en) * 1999-06-29 2003-06-17 Palatin Technologies, Inc. Compositions and methods for treatment of sexual dysfunction
GB0010183D0 (en) * 2000-04-26 2000-06-14 Ferring Bv Inhibitors of dipeptidyl peptidase IV
AU2002359364A1 (en) * 2001-11-09 2003-05-26 Enzon, Inc. Polymeric thiol-linked prodrugs employing benzyl elimination systems
US6974187B2 (en) * 2004-01-28 2005-12-13 Tachi-S Co., Ltd. Vehicle seat structure
CA2939164A1 (en) 2014-02-12 2015-08-20 Iteos Therapeutics Novel 3-(indol-3-yl)-pyridine derivatives, pharmaceutical compositions and methods for use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042064A (en) * 1957-04-02 1962-07-03 Rockwell Mfg Co Gas pressure regulator
US3853836A (en) * 1972-02-22 1974-12-10 Akzona Inc Psychopharmacologically active peptides related to acth
US3856770A (en) * 1972-03-08 1974-12-24 Akzona Inc Psychopharmacologically active tetra-, penta-, hexa-, and heptapeptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175174C (nl) 1972-03-31 1984-10-01 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat met psychofarmacologische werking, dat een peptide of peptide-derivaat als actief bestanddeel bevat, alsmede een werkwijze ter bereiding van deze peptiden.
NL175618C (nl) 1972-07-15 1984-12-03 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat met psychofarmacologische werking, dat een peptide of peptide-derivaat bevat, alsmede een werkwijze ter bereiding van dergelijke peptiden.
NL7607684A (nl) 1976-07-12 1978-01-16 Akzo Nv Werkwijze ter bereiding van nieuwe peptiden en peptide-derivaten en de toepassing hiervan.
IE56254B1 (en) 1982-11-10 1991-06-05 Akzo Nv Peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042064A (en) * 1957-04-02 1962-07-03 Rockwell Mfg Co Gas pressure regulator
US3853836A (en) * 1972-02-22 1974-12-10 Akzona Inc Psychopharmacologically active peptides related to acth
US3856770A (en) * 1972-03-08 1974-12-24 Akzona Inc Psychopharmacologically active tetra-, penta-, hexa-, and heptapeptides

Also Published As

Publication number Publication date
PT81345B (pt) 1987-12-30
EP0179332B1 (de) 1993-01-13
ES548052A0 (es) 1987-02-16
JPS61100596A (ja) 1986-05-19
US4623715A (en) 1986-11-18
ES8703488A1 (es) 1987-02-16
ATE84544T1 (de) 1993-01-15
AU3539484A (en) 1986-05-01
IE852596L (en) 1986-04-22
CS408391A3 (en) 1992-06-17
PT81345A (de) 1985-11-01
EP0179332A3 (en) 1989-02-08
JPH075632B2 (ja) 1995-01-25
US4696913A (en) 1987-09-29
DE3586979D1 (de) 1993-02-25
CA1267996A (en) 1990-04-17
GR852541B ( ) 1986-02-18
DK482185D0 (da) 1985-10-21
IE59724B1 (en) 1994-03-23
DK170649B1 (da) 1995-11-20
DK482185A (da) 1986-04-23
EP0179332A2 (de) 1986-04-30

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