AU546457B2 - Amino acid derivatives for treating depression - Google Patents

Amino acid derivatives for treating depression

Info

Publication number
AU546457B2
AU546457B2 AU84237/82A AU8423782A AU546457B2 AU 546457 B2 AU546457 B2 AU 546457B2 AU 84237/82 A AU84237/82 A AU 84237/82A AU 8423782 A AU8423782 A AU 8423782A AU 546457 B2 AU546457 B2 AU 546457B2
Authority
AU
Australia
Prior art keywords
amino acid
acid derivatives
treating depression
depression
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU84237/82A
Other languages
English (en)
Other versions
AU8423782A (en
Inventor
Ian A. Mcdonald
Michael G. Palfreyman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/268,554 external-priority patent/US4346110A/en
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of AU8423782A publication Critical patent/AU8423782A/en
Application granted granted Critical
Publication of AU546457B2 publication Critical patent/AU546457B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU84237/82A 1981-06-01 1982-05-27 Amino acid derivatives for treating depression Ceased AU546457B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26855381A 1981-06-01 1981-06-01
US268554 1981-06-01
US06/268,554 US4346110A (en) 1981-06-01 1981-06-01 Method for treating depression
US268553 1981-06-01

Publications (2)

Publication Number Publication Date
AU8423782A AU8423782A (en) 1982-12-09
AU546457B2 true AU546457B2 (en) 1985-09-05

Family

ID=26953167

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84237/82A Ceased AU546457B2 (en) 1981-06-01 1982-05-27 Amino acid derivatives for treating depression

Country Status (16)

Country Link
EP (1) EP0066518B1 (enExample)
KR (1) KR890002771B1 (enExample)
AU (1) AU546457B2 (enExample)
CA (1) CA1190242A (enExample)
DE (1) DE3271642D1 (enExample)
DK (1) DK152425C (enExample)
ES (1) ES512700A0 (enExample)
GB (1) GB2102411B (enExample)
GR (1) GR75480B (enExample)
HK (1) HK90586A (enExample)
IE (1) IE53458B1 (enExample)
IL (1) IL65809A (enExample)
MY (1) MY8600721A (enExample)
NO (1) NO161438C (enExample)
NZ (1) NZ200643A (enExample)
SG (1) SG63686G (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101602687A (zh) * 2008-06-13 2009-12-16 上海特化医药科技有限公司 6-硝基苯乙酮类化合物、其制备方法及用途
US8669267B2 (en) * 2008-08-21 2014-03-11 Suntory Holdings Limited Pharmaceutical, food or beverage having inhibitory activity on serotonin transporter

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4275220A (en) * 1979-08-06 1981-06-23 Merck & Co., Inc. Process for preparing amino acids and esters

Also Published As

Publication number Publication date
NO161438B (no) 1989-05-08
ES8306472A1 (es) 1983-06-01
IL65809A (en) 1986-07-31
IE53458B1 (en) 1988-11-23
NO821798L (no) 1982-12-02
KR890002771B1 (ko) 1989-07-28
DE3271642D1 (en) 1986-07-17
CA1190242A (en) 1985-07-09
GR75480B (enExample) 1984-07-23
EP0066518A3 (en) 1984-02-29
NZ200643A (en) 1986-06-11
HK90586A (en) 1986-12-05
GB2102411A (en) 1983-02-02
GB2102411B (en) 1984-12-05
DK152425B (da) 1988-02-29
KR830010047A (ko) 1983-12-24
NO161438C (no) 1989-08-16
EP0066518A2 (en) 1982-12-08
AU8423782A (en) 1982-12-09
MY8600721A (en) 1986-12-31
ES512700A0 (es) 1983-06-01
DK244482A (da) 1982-12-02
EP0066518B1 (en) 1986-06-11
SG63686G (en) 1987-03-27
IE821247L (en) 1982-12-01
DK152425C (da) 1988-08-22

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired