DK152425C - Analogifremgangsmaade til fremstilling af alfa-amino-buten-3-carboxylsyrer eller farmaceutisk acceptable ikke toksiske salte deraf i form af racemater eller rene enantiomere - Google Patents
Analogifremgangsmaade til fremstilling af alfa-amino-buten-3-carboxylsyrer eller farmaceutisk acceptable ikke toksiske salte deraf i form af racemater eller rene enantiomereInfo
- Publication number
- DK152425C DK152425C DK244482A DK244482A DK152425C DK 152425 C DK152425 C DK 152425C DK 244482 A DK244482 A DK 244482A DK 244482 A DK244482 A DK 244482A DK 152425 C DK152425 C DK 152425C
- Authority
- DK
- Denmark
- Prior art keywords
- buten
- alfa
- racemates
- analogue
- amino
- Prior art date
Links
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- 231100000252 nontoxic Toxicity 0.000 title 1
- 230000003000 nontoxic effect Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26855381A | 1981-06-01 | 1981-06-01 | |
| US06/268,554 US4346110A (en) | 1981-06-01 | 1981-06-01 | Method for treating depression |
| US26855381 | 1981-06-01 | ||
| US26855481 | 1981-06-01 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK244482A DK244482A (da) | 1982-12-02 |
| DK152425B DK152425B (da) | 1988-02-29 |
| DK152425C true DK152425C (da) | 1988-08-22 |
Family
ID=26953167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK244482A DK152425C (da) | 1981-06-01 | 1982-05-28 | Analogifremgangsmaade til fremstilling af alfa-amino-buten-3-carboxylsyrer eller farmaceutisk acceptable ikke toksiske salte deraf i form af racemater eller rene enantiomere |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0066518B1 (da) |
| KR (1) | KR890002771B1 (da) |
| AU (1) | AU546457B2 (da) |
| CA (1) | CA1190242A (da) |
| DE (1) | DE3271642D1 (da) |
| DK (1) | DK152425C (da) |
| ES (1) | ES8306472A1 (da) |
| GB (1) | GB2102411B (da) |
| GR (1) | GR75480B (da) |
| HK (1) | HK90586A (da) |
| IE (1) | IE53458B1 (da) |
| IL (1) | IL65809A (da) |
| MY (1) | MY8600721A (da) |
| NO (1) | NO161438C (da) |
| NZ (1) | NZ200643A (da) |
| SG (1) | SG63686G (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101602687A (zh) * | 2008-06-13 | 2009-12-16 | 上海特化医药科技有限公司 | 6-硝基苯乙酮类化合物、其制备方法及用途 |
| JP5400779B2 (ja) * | 2008-08-21 | 2014-01-29 | サントリーホールディングス株式会社 | セロトニントランスポーター阻害活性を有する医薬品又は飲食品 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4275220A (en) * | 1979-08-06 | 1981-06-23 | Merck & Co., Inc. | Process for preparing amino acids and esters |
-
1982
- 1982-05-17 NZ NZ200643A patent/NZ200643A/en unknown
- 1982-05-17 IL IL65809A patent/IL65809A/xx not_active IP Right Cessation
- 1982-05-21 GB GB08214890A patent/GB2102411B/en not_active Expired
- 1982-05-25 IE IE1247/82A patent/IE53458B1/en not_active IP Right Cessation
- 1982-05-27 EP EP82400990A patent/EP0066518B1/en not_active Expired
- 1982-05-27 DE DE8282400990T patent/DE3271642D1/de not_active Expired
- 1982-05-27 AU AU84237/82A patent/AU546457B2/en not_active Ceased
- 1982-05-28 CA CA000403964A patent/CA1190242A/en not_active Expired
- 1982-05-28 NO NO821798A patent/NO161438C/no not_active IP Right Cessation
- 1982-05-28 DK DK244482A patent/DK152425C/da not_active IP Right Cessation
- 1982-05-31 GR GR68305A patent/GR75480B/el unknown
- 1982-05-31 ES ES512700A patent/ES8306472A1/es not_active Expired
- 1982-05-31 KR KR8202442A patent/KR890002771B1/ko not_active Expired
-
1986
- 1986-07-22 SG SG63686A patent/SG63686G/en unknown
- 1986-11-27 HK HK905/86A patent/HK90586A/xx not_active IP Right Cessation
- 1986-12-30 MY MY721/86A patent/MY8600721A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB2102411A (en) | 1983-02-02 |
| GB2102411B (en) | 1984-12-05 |
| NZ200643A (en) | 1986-06-11 |
| SG63686G (en) | 1987-03-27 |
| MY8600721A (en) | 1986-12-31 |
| ES512700A0 (es) | 1983-06-01 |
| AU546457B2 (en) | 1985-09-05 |
| DE3271642D1 (en) | 1986-07-17 |
| KR830010047A (ko) | 1983-12-24 |
| DK152425B (da) | 1988-02-29 |
| EP0066518A2 (en) | 1982-12-08 |
| IL65809A (en) | 1986-07-31 |
| GR75480B (da) | 1984-07-23 |
| IE821247L (en) | 1982-12-01 |
| IE53458B1 (en) | 1988-11-23 |
| EP0066518A3 (en) | 1984-02-29 |
| KR890002771B1 (ko) | 1989-07-28 |
| NO821798L (no) | 1982-12-02 |
| NO161438C (no) | 1989-08-16 |
| NO161438B (no) | 1989-05-08 |
| AU8423782A (en) | 1982-12-09 |
| DK244482A (da) | 1982-12-02 |
| CA1190242A (en) | 1985-07-09 |
| HK90586A (en) | 1986-12-05 |
| ES8306472A1 (es) | 1983-06-01 |
| EP0066518B1 (en) | 1986-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |