AU528186B2 - Microparticles for delivering drugs to female reproductive organs - Google Patents

Microparticles for delivering drugs to female reproductive organs

Info

Publication number
AU528186B2
AU528186B2 AU51696/79A AU5169679A AU528186B2 AU 528186 B2 AU528186 B2 AU 528186B2 AU 51696/79 A AU51696/79 A AU 51696/79A AU 5169679 A AU5169679 A AU 5169679A AU 528186 B2 AU528186 B2 AU 528186B2
Authority
AU
Australia
Prior art keywords
microparticles
cervix
hormone
uterus
progesterone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU51696/79A
Other languages
English (en)
Other versions
AU5169679A (en
Inventor
Lee R. Beck
Donald R. Cowsar
Charles F Flowers Jr.
Albert C. Tanquary
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stolle Research and Development Corp
Original Assignee
Stolle Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stolle Research and Development Corp filed Critical Stolle Research and Development Corp
Publication of AU5169679A publication Critical patent/AU5169679A/en
Application granted granted Critical
Publication of AU528186B2 publication Critical patent/AU528186B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU51696/79A 1978-10-17 1979-10-11 Microparticles for delivering drugs to female reproductive organs Ceased AU528186B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95210978A 1978-10-17 1978-10-17
US952109 1978-10-17
US96738078A 1978-12-07 1978-12-07
US967380 1978-12-07

Publications (2)

Publication Number Publication Date
AU5169679A AU5169679A (en) 1980-04-24
AU528186B2 true AU528186B2 (en) 1983-04-21

Family

ID=27130325

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51696/79A Ceased AU528186B2 (en) 1978-10-17 1979-10-11 Microparticles for delivering drugs to female reproductive organs

Country Status (13)

Country Link
AU (1) AU528186B2 (enExample)
CA (1) CA1143289A (enExample)
CH (1) CH645545A5 (enExample)
DE (1) DE2940146A1 (enExample)
FR (1) FR2439014A1 (enExample)
GB (1) GB2034182B (enExample)
IE (1) IE48851B1 (enExample)
IL (1) IL58471A (enExample)
IT (1) IT1124572B (enExample)
NL (1) NL184723C (enExample)
NZ (1) NZ191837A (enExample)
PH (1) PH25638A (enExample)
SE (1) SE7908520L (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US5366734A (en) * 1981-02-16 1994-11-22 Zeneca Limited Continuous release pharmaceutical compositions
CH661206A5 (fr) * 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
US4816257A (en) * 1985-09-20 1989-03-28 Research & Education Institute, Harbor-Ucla Medical Center Inc. Method for producing an in vivo environment suitable for human embryo transfer
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US5000886A (en) * 1987-05-26 1991-03-19 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules and process of making the same
EP0300102B1 (en) * 1987-07-21 1993-03-24 The Stolle Research And Development Corporation Improved method of obtaining immune regulatory factors by mammal immunization
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
FR2620335A1 (fr) * 1987-09-15 1989-03-17 Berdal Pascal Presentation pharmaceutique potentialisant l'effet cytotrophique des serums et/ou des anticorps antitissus animaux et/ou humains
US5084277A (en) * 1988-08-30 1992-01-28 Greco John C Vaginal progesterone tablet
US5922340A (en) 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5942241A (en) 1995-06-09 1999-08-24 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
AU733867B2 (en) 1996-06-24 2001-05-31 Euro-Celtique S.A. Methods for providing safe local anesthesia
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
IL129951A0 (en) 1997-07-02 2000-02-29 Euro Celtique Sa Prolonged anesthesia in joints and body spaces

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3594468A (en) * 1969-04-01 1971-07-20 Vincent R Saurino Germicidal compositions
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
AU513400B2 (en) * 1976-03-04 1980-11-27 Commonwealth Serum Laboratories Commission Biodegradable, sustained release composition

Also Published As

Publication number Publication date
NL184723C (nl) 1989-10-16
GB2034182A (en) 1980-06-04
CA1143289A (en) 1983-03-22
SE7908520L (sv) 1980-04-18
NZ191837A (en) 1984-07-31
DE2940146A1 (de) 1980-04-30
IT7926288A0 (it) 1979-10-05
PH25638A (en) 1991-08-31
GB2034182B (en) 1983-07-27
IE48851B1 (en) 1985-05-29
IE791966L (en) 1980-04-17
NL7907432A (nl) 1980-04-21
IL58471A (en) 1983-05-15
FR2439014A1 (fr) 1980-05-16
NL184723B (nl) 1989-05-16
AU5169679A (en) 1980-04-24
CH645545A5 (de) 1984-10-15
FR2439014B1 (enExample) 1983-12-09
IL58471A0 (en) 1980-01-31
IT1124572B (it) 1986-05-07
DE2940146C2 (enExample) 1991-12-05

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