AU517830B2 - Piperidine derivatives - Google Patents

Piperidine derivatives

Info

Publication number
AU517830B2
AU517830B2 AU30673/77A AU3067377A AU517830B2 AU 517830 B2 AU517830 B2 AU 517830B2 AU 30673/77 A AU30673/77 A AU 30673/77A AU 3067377 A AU3067377 A AU 3067377A AU 517830 B2 AU517830 B2 AU 517830B2
Authority
AU
Australia
Prior art keywords
group
general formula
methoxy
amino
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU30673/77A
Other languages
English (en)
Other versions
AU3067377A (en
Inventor
A. V. Dr. ET AL Noverola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fordonal SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of AU3067377A publication Critical patent/AU3067377A/en
Application granted granted Critical
Publication of AU517830B2 publication Critical patent/AU517830B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU30673/77A 1976-11-16 1977-11-15 Piperidine derivatives Expired AU517830B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB47739/76A GB1574418A (en) 1976-11-16 1976-11-16 Piperidine derivatives
GBGB47739/76 1979-11-16

Publications (2)

Publication Number Publication Date
AU3067377A AU3067377A (en) 1979-05-24
AU517830B2 true AU517830B2 (en) 1981-08-27

Family

ID=10446086

Family Applications (2)

Application Number Title Priority Date Filing Date
AU30673/77A Expired AU517830B2 (en) 1976-11-16 1977-11-15 Piperidine derivatives
AU30672/77A Expired AU517004B2 (en) 1976-11-16 1977-11-15 Piperidine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU30672/77A Expired AU517004B2 (en) 1976-11-16 1977-11-15 Piperidine derivatives

Country Status (13)

Country Link
US (1) US5026858A (enExample)
JP (2) JPS5390267A (enExample)
AT (2) AT360013B (enExample)
AU (2) AU517830B2 (enExample)
BE (2) BE860737A (enExample)
CA (2) CA1094072A (enExample)
DE (2) DE2751139A1 (enExample)
ES (4) ES464146A1 (enExample)
FR (2) FR2370733A1 (enExample)
GB (1) GB1574418A (enExample)
IE (2) IE45989B1 (enExample)
NL (2) NL7712570A (enExample)
ZA (2) ZA776587B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives
FR2546169B1 (fr) * 1983-05-20 1986-03-21 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
US5011992A (en) * 1984-06-28 1991-04-30 Bristol-Myers Squibb Company Pharmacologically active substituted benzamides
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
GB8519707D0 (en) * 1985-08-06 1985-09-11 Fordonal Sa Chemical compounds
JP2909214B2 (ja) * 1992-08-19 1999-06-23 フアイザー・インコーポレイテツド 置換ベンジルアミノ窒素含有非芳香族複素環化合物
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
US6339087B1 (en) 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
ATE386720T1 (de) * 1998-11-20 2008-03-15 Hoffmann La Roche Piperidin ccr-3 rezeptor-hemmer
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TW200800953A (en) * 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
JP2007524641A (ja) * 2003-07-11 2007-08-30 セラヴァンス， インコーポレーテッド 置換４−アミノ−１−ベンジルピペリジン化合物
WO2005053663A2 (en) * 2003-11-24 2005-06-16 Eli Lilly And Company Norepinephrine reuptake inhibitors useful for treatment of cognitive failure
BRPI0611138A2 (pt) * 2005-06-02 2010-08-17 Hoffmann La Roche compostos, processo para a manufatura dos mesmos, composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de sst subtipo 5 e utilização dos compostos
JP2009264436A (ja) 2008-04-23 2009-11-12 Funai Electric Co Ltd トルクリミッタ装置、トルクリミッタ装置を備えた表示画面旋回装置およびトルクリミッタ装置を含むテレビジョン装置
CN119679732B (zh) * 2024-12-11 2025-10-10 北京阳光诺和药物研究股份有限公司 一种胃肠促动力片剂及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1019781A (enExample) * 1963-03-05
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (enExample) * 1966-01-21 1968-05-06
US3577440A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-amido-pyrrolidines
GB1345872A (en) * 1970-09-03 1974-02-06 Wyeth John & Brother Ltd Amino-and acylamino-pyridine and hydropyridine derivatives
US3963745A (en) * 1972-04-03 1976-06-15 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
GB1513631A (en) * 1976-02-17 1978-06-07 Gallardo Antonio Sa Piperidine derivatives
US4163789A (en) * 1976-02-17 1979-08-07 Anphar, S.A. Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives

Also Published As

Publication number Publication date
FR2370732A1 (fr) 1978-06-09
NL7712570A (nl) 1978-05-18
US5026858A (en) 1991-06-25
AU3067377A (en) 1979-05-24
FR2370732B1 (enExample) 1980-07-04
DE2751138A1 (de) 1978-05-24
NL7712559A (nl) 1978-05-18
BE860737A (fr) 1978-03-01
IE46090B1 (en) 1983-02-23
ES464145A1 (es) 1978-09-01
ES464144A1 (es) 1978-09-01
ZA776588B (en) 1978-08-30
CA1094072A (en) 1981-01-20
GB1574418A (en) 1980-09-03
FR2370733B1 (enExample) 1980-07-04
IE45989L (en) 1978-05-16
ATA817077A (de) 1980-05-15
AT360013B (de) 1980-12-10
FR2370733A1 (fr) 1978-06-09
ZA776587B (en) 1978-09-27
IE45989B1 (en) 1983-01-26
IE46090L (en) 1978-05-16
CA1095046A (en) 1981-02-03
AT360014B (de) 1980-12-10
JPS6126782B2 (enExample) 1986-06-21
ES464146A1 (es) 1978-09-01
DE2751139A1 (de) 1978-05-24
ATA817177A (de) 1980-05-15
JPS5390267A (en) 1978-08-08
AU517004B2 (en) 1981-07-02
ES464147A1 (es) 1978-09-01
BE860736A (fr) 1978-03-01
JPS5387365A (en) 1978-08-01
AU3067277A (en) 1979-05-24
JPS6127388B2 (enExample) 1986-06-25

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