AU5115393A - Novel derivatives of taxol analogues, preparation thereof and compositions containing them - Google Patents

Novel derivatives of taxol analogues, preparation thereof and compositions containing them

Info

Publication number
AU5115393A
AU5115393A AU51153/93A AU5115393A AU5115393A AU 5115393 A AU5115393 A AU 5115393A AU 51153/93 A AU51153/93 A AU 51153/93A AU 5115393 A AU5115393 A AU 5115393A AU 5115393 A AU5115393 A AU 5115393A
Authority
AU
Australia
Prior art keywords
preparation
compositions containing
novel derivatives
taxol analogues
taxol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU51153/93A
Other languages
English (en)
Inventor
Jean-Dominique Bourzat
Alain Commercon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of AU5115393A publication Critical patent/AU5115393A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
AU51153/93A 1992-10-05 1993-10-04 Novel derivatives of taxol analogues, preparation thereof and compositions containing them Abandoned AU5115393A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9211744 1992-10-05
FR9211744A FR2696461B1 (fr) 1992-10-05 1992-10-05 Nouveaux dérivés d'analogues du taxol, leur préparation et les compositions qui les contiennent.
PCT/FR1993/000970 WO1994007880A1 (fr) 1992-10-05 1993-10-04 Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent

Publications (1)

Publication Number Publication Date
AU5115393A true AU5115393A (en) 1994-04-26

Family

ID=9434122

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51153/93A Abandoned AU5115393A (en) 1992-10-05 1993-10-04 Novel derivatives of taxol analogues, preparation thereof and compositions containing them

Country Status (5)

Country Link
AU (1) AU5115393A (fr)
FR (1) FR2696461B1 (fr)
MX (1) MX9305769A (fr)
WO (1) WO1994007880A1 (fr)
ZA (1) ZA937321B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2290074T3 (es) 1993-07-19 2008-02-16 Angiotech Pharmaceuticals, Inc. Composiciones anti-angiogenicas que contienen taxol y un vehiculo no biodegradable y su uso.
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
ES2151277T3 (es) * 1996-05-22 2000-12-16 Protarga Inc Composiciones que comprenden conjugados de acido cis-docosahexaenoico y taxotere.
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
WO1998013359A1 (fr) * 1996-09-24 1998-04-02 Marigen S.A. Ultramicroemulsions constituees de concentres pouvant etre disperses de façon spontanne, renfermant des esters de composes de baccatine-iii a effet antitumoral et antiviral
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2307393A1 (fr) 2000-05-01 2001-11-01 The University Of British Columbia Chimiotherapie par administration d'un ginsenoside
US20030054036A1 (en) 2001-03-13 2003-03-20 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
DE60220519T2 (de) 2001-04-20 2007-09-27 The University Of British Columbia, Vancouver Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe
CA2354471A1 (fr) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. Taxanes substitues avec un ester en c10
US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
US20040225077A1 (en) 2002-12-30 2004-11-11 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US20070172446A1 (en) 2003-05-16 2007-07-26 Intermune, Inc. Synthetic chemokine receptor ligands and methods of use thereof
PE20050693A1 (es) 2004-02-13 2005-09-27 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
US7846940B2 (en) 2004-03-31 2010-12-07 Cordis Corporation Solution formulations of sirolimus and its analogs for CAD treatment
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
US20060188508A1 (en) 2005-02-17 2006-08-24 Cohen Stanley N Methods and compositions for modulating angiogenesis
CA2646156C (fr) 2006-03-22 2016-05-24 Medigene Ag Traitement du cancer du sein avec = triple recepteur negatif =
WO2008005284A2 (fr) 2006-06-30 2008-01-10 Cook Incorporated Procédés de production et de modification de revêtements en taxane destinés à des dispositifs médicaux implantables
CA2718567A1 (fr) 2008-03-31 2009-12-03 Florida State University Research Foundation, Inc. Taxanes substitues par un ester ethylique en c(10) et un ester cyclopropylique en c(10)
US8420110B2 (en) 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US8273404B2 (en) 2008-05-19 2012-09-25 Cordis Corporation Extraction of solvents from drug containing polymer reservoirs
WO2009143454A2 (fr) 2008-05-22 2009-11-26 Kereos, Inc. Combinaison thérapeutique anticancéreuse
WO2010005850A1 (fr) 2008-07-08 2010-01-14 The J. David Gladstone Institutes Procédés et compositions de modulation de l’angiogenèse
US8642063B2 (en) 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
US20120303115A1 (en) 2011-05-25 2012-11-29 Dadino Ronald C Expandable devices coated with a rapamycin composition
US20120302954A1 (en) 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
JP6578206B2 (ja) 2012-07-19 2019-09-18 レッドウッド バイオサイエンス， インコーポレイテッド Ｃｄ２２に特異的な抗体およびその使用方法
WO2014074218A1 (fr) 2012-11-12 2014-05-15 Redwood Bioscience, Inc. Composés et procédés pour produire un conjugué
SI3613439T1 (sl) 2013-02-15 2021-11-30 The Regents Of The University Of California Himerni antigenski receptor in postopki njegove uporabe
CN105358531B (zh) 2013-03-14 2017-11-14 利兰-斯坦福大学初级学院的董事会 线粒体醛脱氢酶‑2调节剂和其使用方法
US9493413B2 (en) 2013-11-27 2016-11-15 Redwood Bioscience, Inc. Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
EP3107899B1 (fr) 2014-02-19 2020-08-12 Aviv Therapeutics, Inc. Amides polycycliques se liant à l'aldéhyde déshydrogénase 2 mitochondriale (aldh2) et leur utilisation pour le traitement du cancer
US10517961B2 (en) 2015-09-25 2019-12-31 ZY Therapeutics, Inc. Drug formulation based on particulates comprising polysaccharide-vitamin conjugate
WO2017083637A1 (fr) 2015-11-12 2017-05-18 The Board Of Trustees Of The Leland Stanford Junior University Oligophosphotriesters riches en guanidinium à pénétration cellulaire pour l'administration de médicament et de sonde
TWI760319B (zh) 2015-12-30 2022-04-11 杏國新藥股份有限公司 乳癌治療
AU2017257504A1 (en) 2016-04-26 2018-10-25 R.P. Scherer Technologies, Llc Antibody conjugates and methods of making and using the same
EP3463308B1 (fr) 2016-06-01 2021-12-01 Servier IP UK Limited Formulations d'oxyde de polyalkylène-asparaginase et leurs procédés de fabrication et d'utilisation
MX2019008503A (es) 2017-01-18 2019-09-13 F1 Oncology Inc Receptores de antigenos quimericos contra axl o ror2 y metodos de uso de los mismos.
EP3388082A1 (fr) 2017-04-13 2018-10-17 Galera Labs, LLC Poly-immunothérapie anticancéreuse avec un complexe de cycle pentaaza macrocyclique
CN111902147A (zh) 2018-01-31 2020-11-06 加莱拉实验室有限责任公司 五氮杂大环状环配合物和基于铂的抗癌剂的组合癌症治疗
CA3096838A1 (fr) 2018-04-11 2019-10-17 Ohio State Innovation Foundation Procedes et compositions pour microparticules a liberation prolongee pour l'administration de medicament oculaire
CA3105879A1 (fr) 2018-07-18 2020-01-23 Manzanita Pharmaceuticals, Inc. Conjugues pour administrer un agent anticancereux a des cellules nerveuses, methodes d'utilisation et leurs procedes de fabrication
WO2020148612A1 (fr) 2019-01-14 2020-07-23 Ignite Immunotherapy, Inc. Virus de la vaccine recombinant et ses procédés d'utilisation
US11685904B2 (en) 2019-02-14 2023-06-27 Ignite Immunotherapy, Inc. Recombinant vaccinia virus and methods of use thereof
CA3131895A1 (fr) 2019-04-02 2020-10-08 Kenjockety Biotechnology, Inc. Anticorps multi-specifiques d'un antigene associe a un cancer et d'une pompe d'efflux, ainsi que compositions, reactifs, kits et methodes associes a ceux-ci
US20230002740A1 (en) 2019-12-12 2023-01-05 Ignite Immunotherapy, Inc Variant oncolytic vaccinia virus and methods of use thereof
CN115023443A (zh) 2020-01-29 2022-09-06 肯乔克蒂生物技术股份有限公司 抗mdr1抗体及其用途
US20230192902A1 (en) 2020-06-04 2023-06-22 Kenjockety Biotechnology, Inc. Abcg2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto
JP2023528416A (ja) 2020-06-04 2023-07-04 ケンジョッケティ バイオテクノロジー，インク． 抗ａｂｃｇ２抗体及びそれらの使用
KR20230023032A (ko) 2020-07-14 2023-02-16 화이자 인코포레이티드 재조합 백시니아 바이러스
WO2022051390A1 (fr) 2020-09-02 2022-03-10 Kenjockety Biotechnology, Inc. Anticorps anti-abcc1 et leurs utilisations
WO2022103603A1 (fr) 2020-11-13 2022-05-19 Kenjockety Biotechnology, Inc. Anticorps anti-mrp4 (codés par le gène abcc4) et leurs utilisations
WO2023114658A1 (fr) 2021-12-13 2023-06-22 Kenjockety Biotechnology, Inc. Anticorps anti-abcb1
WO2023159220A1 (fr) 2022-02-18 2023-08-24 Kenjockety Biotechnology, Inc. Anticorps anti-cd47

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ZA937321B (en) 1994-04-25
FR2696461A1 (fr) 1994-04-08
WO1994007880A1 (fr) 1994-04-14
MX9305769A (es) 1994-05-31
FR2696461B1 (fr) 1994-11-10

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