AU509372B2 - 2-Phenyl-3-Aroylbenzothiophane Derivatives and their use as Antifertility Agents - Google Patents

2-Phenyl-3-Aroylbenzothiophane Derivatives and their use as Antifertility Agents

Info

Publication number
AU509372B2
AU509372B2 AU19004/76A AU1900476A AU509372B2 AU 509372 B2 AU509372 B2 AU 509372B2 AU 19004/76 A AU19004/76 A AU 19004/76A AU 1900476 A AU1900476 A AU 1900476A AU 509372 B2 AU509372 B2 AU 509372B2
Authority
AU
Australia
Prior art keywords
aroylbenzothiophane
phenyl
derivatives
antifertility agents
antifertility
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU19004/76A
Other languages
English (en)
Other versions
AU1900476A (en
Inventor
C. D. and Suarez T Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU1900476A publication Critical patent/AU1900476A/en
Application granted granted Critical
Publication of AU509372B2 publication Critical patent/AU509372B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid
AU19004/76A 1975-10-28 1976-10-26 2-Phenyl-3-Aroylbenzothiophane Derivatives and their use as Antifertility Agents Expired AU509372B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62599175A 1975-10-28 1975-10-28
USUS625991 1975-10-28

Publications (2)

Publication Number Publication Date
AU1900476A AU1900476A (en) 1978-05-04
AU509372B2 true AU509372B2 (en) 1980-05-08

Family

ID=24508491

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19004/76A Expired AU509372B2 (en) 1975-10-28 1976-10-26 2-Phenyl-3-Aroylbenzothiophane Derivatives and their use as Antifertility Agents

Country Status (30)

Country Link
JP (1) JPS6045191B2 (de)
AR (1) AR214622A1 (de)
AT (1) AT346321B (de)
AU (1) AU509372B2 (de)
BE (1) BE847716A (de)
BG (1) BG27555A3 (de)
CA (1) CA1078834A (de)
CH (2) CH624398A5 (de)
CS (1) CS235057B2 (de)
DD (1) DD127460A5 (de)
DE (1) DE2646213A1 (de)
DK (1) DK484776A (de)
ES (1) ES452735A1 (de)
FR (1) FR2329264A1 (de)
GB (1) GB1561687A (de)
GR (1) GR61816B (de)
HU (1) HU175227B (de)
IE (1) IE43641B1 (de)
IL (1) IL50772A (de)
MX (1) MX4291E (de)
NL (1) NL187164C (de)
NZ (1) NZ182421A (de)
PH (1) PH14538A (de)
PL (2) PL104551B1 (de)
PT (1) PT65752B (de)
RO (1) RO70755A (de)
SE (1) SE428689B (de)
SU (2) SU791220A3 (de)
YU (1) YU262276A (de)
ZA (1) ZA766439B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179558A (en) * 1978-01-30 1979-12-18 E. R. Squibb & Sons, Inc. Naphthalenone derivatives and analogs
DE3121175A1 (de) * 1981-05-27 1982-12-16 Klinge Pharma GmbH, 8000 München Erythro-1,2,3-triphenyl-1-pentanon-derivate sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH0717589B2 (ja) * 1990-01-22 1995-03-01 ファイザー製薬株式会社 新規１，３―ジカルボニル化合物およびその組成物
US6391892B1 (en) * 1995-03-10 2002-05-21 Eli Lilly And Company Naphthyl pharmaceutical compounds

Also Published As

Publication number Publication date
GB1561687A (en) 1980-02-27
PT65752B (en) 1978-04-20
AT346321B (de) 1978-11-10
RO70755A (ro) 1981-01-30
NL7611974A (nl) 1977-05-02
SU818476A3 (ru) 1981-03-30
DK484776A (da) 1977-04-29
PL111987B1 (en) 1980-09-30
AR214622A1 (es) 1979-07-13
CH624376A5 (en) 1981-07-31
FR2329264B1 (de) 1978-11-17
CH624398A5 (en) 1981-07-31
SU791220A3 (ru) 1980-12-23
ATA800576A (de) 1978-03-15
ES452735A1 (es) 1978-01-01
DE2646213A1 (de) 1977-05-12
AU1900476A (en) 1978-05-04
MX4291E (es) 1982-03-17
DD127460A5 (de) 1977-09-28
PH14538A (en) 1981-09-24
JPS5253845A (en) 1977-04-30
JPS6045191B2 (ja) 1985-10-08
DE2646213C2 (de) 1987-02-12
GR61816B (en) 1979-01-22
CS235057B2 (en) 1985-04-16
SE7611953L (sv) 1977-04-29
IE43641B1 (en) 1981-04-22
HU175227B (hu) 1980-06-28
YU262276A (en) 1982-05-31
FR2329264A1 (fr) 1977-05-27
NZ182421A (en) 1978-11-13
NL187164B (nl) 1991-01-16
IL50772A0 (en) 1976-12-31
CA1078834A (en) 1980-06-03
IL50772A (en) 1980-11-30
PL104551B1 (pl) 1979-08-31
BG27555A3 (en) 1979-11-12
PT65752A (en) 1976-11-01
ZA766439B (en) 1978-06-28
SE428689B (sv) 1983-07-18
NL187164C (nl) 1991-06-17
BE847716A (fr) 1977-04-28
IE43641L (en) 1977-04-28

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