AU509357B2 - Prostacyclin analogs - Google Patents

Prostacyclin analogs

Info

Publication number
AU509357B2
AU509357B2 AU28206/77A AU2820677A AU509357B2 AU 509357 B2 AU509357 B2 AU 509357B2 AU 28206/77 A AU28206/77 A AU 28206/77A AU 2820677 A AU2820677 A AU 2820677A AU 509357 B2 AU509357 B2 AU 509357B2
Authority
AU
Australia
Prior art keywords
prostacyclin analogs
prostacyclin
analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU28206/77A
Other languages
English (en)
Other versions
AU2820677A (en
Inventor
RA. and Sid JC Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU2820677A publication Critical patent/AU2820677A/en
Application granted granted Critical
Publication of AU509357B2 publication Critical patent/AU509357B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
AU28206/77A 1977-04-19 1977-08-25 Prostacyclin analogs Expired AU509357B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78814377A 1977-04-19 1977-04-19
US78814477A 1977-04-19 1977-04-19
USUS788143 1977-04-19
USUS788144 1977-04-19

Publications (2)

Publication Number Publication Date
AU2820677A AU2820677A (en) 1979-03-01
AU509357B2 true AU509357B2 (en) 1980-05-08

Family

ID=27120750

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28206/77A Expired AU509357B2 (en) 1977-04-19 1977-08-25 Prostacyclin analogs

Country Status (9)

Country Link
JP (1) JPS53132573A (el)
AU (1) AU509357B2 (el)
CA (1) CA1184906A (el)
CH (1) CH636347A5 (el)
DE (1) DE2746932A1 (el)
FR (1) FR2387975A1 (el)
GB (1) GB1554050A (el)
NL (1) NL7800011A (el)
SE (1) SE434266B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2
JPH02294718A (ja) * 1989-05-09 1990-12-05 Fujitsu Ltd ディジタル信号入力回路
PT1220849E (pt) * 1999-10-15 2004-10-29 Sucampo Ag Composicao de compostos biciclicos e metodo para a sua estabilizacao
RU2540330C2 (ru) 2009-07-28 2015-02-10 Оно Фармасьютикал Ко., Лтд. Бициклическое соединение и его применение для медицинских целей
US9029574B2 (en) 2011-01-27 2015-05-12 Ono Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
ES2581852T3 (es) * 2011-01-27 2016-09-07 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
US10899729B2 (en) 2016-06-30 2021-01-26 Ono Pharmaceutical Co.. Ltd. Method for producing bicyclic compound

Also Published As

Publication number Publication date
SE434266B (sv) 1984-07-16
SE7709477L (sv) 1978-10-20
JPS53132573A (en) 1978-11-18
JPS6151597B2 (el) 1986-11-10
FR2387975A1 (fr) 1978-11-17
CA1184906A (en) 1985-04-02
AU2820677A (en) 1979-03-01
NL7800011A (nl) 1978-10-23
DE2746932C2 (el) 1988-03-31
FR2387975B1 (el) 1980-08-08
CH636347A5 (en) 1983-05-31
DE2746932A1 (de) 1978-11-02
GB1554050A (en) 1979-10-17

Similar Documents

Publication Publication Date Title
AU520091B2 (en) Prostacyclin analog
AU523593B2 (en) Prostaglandin i2 derivatives
AU536416B2 (en) Prostacyclin analogs
AU523420B2 (en) Prostacyclin derivatives
GB2010247B (en) Prostacyclin derivatives
AU509357B2 (en) Prostacyclin analogs
AU4019778A (en) Prostacyclin analogs
GB2001311B (en) Prostaglandin derivatives
AU522799B2 (en) Prostaglandin analogs
ZA781608B (en) Prostaglandin analogs
AU527238B2 (en) Prostaglandin derivatives
GB2009169B (en) Prostacyclin derivatives
AU3583378A (en) Prostacyclin analogs
AU508355B2 (en) Prostaglandin derivatives
GB2002363B (en) Prostacyclin analogues
AU519080B2 (en) Prostaglandin analogs
AU512960B2 (en) Exo-amide prostaglandin analogues
AU529836B2 (en) Prostaglandin analog
ZA775105B (en) Prostacyclin analogs
AU537584B2 (en) Prostaglandin analogues
AU527253B2 (en) Prostacyclin intermediates
GB2009160B (en) Prostacyclin derivatives
AU8328382A (en) Prostaglandin derivatives
AU3256178A (en) Prostaglandin analogs
ZA783704B (en) Novel prostaglandin derivatives