AU4688799A - Non-enzymatic chemical amidation process - Google Patents

Non-enzymatic chemical amidation process Download PDF

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Publication number
AU4688799A
AU4688799A AU46887/99A AU4688799A AU4688799A AU 4688799 A AU4688799 A AU 4688799A AU 46887/99 A AU46887/99 A AU 46887/99A AU 4688799 A AU4688799 A AU 4688799A AU 4688799 A AU4688799 A AU 4688799A
Authority
AU
Australia
Prior art keywords
peptide
terminal
amino
oxy
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46887/99A
Other languages
English (en)
Inventor
Binyamin Feibush
Stephen R. Jones
Lincoln A. Noecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Magainin Pharmaceuticals Inc
Original Assignee
Magainin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magainin Pharmaceuticals Inc filed Critical Magainin Pharmaceuticals Inc
Publication of AU4688799A publication Critical patent/AU4688799A/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/124—Hydrazinolysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
AU46887/99A 1998-06-17 1999-06-17 Non-enzymatic chemical amidation process Abandoned AU4688799A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8963598P 1998-06-17 1998-06-17
US60089635 1998-06-17
PCT/US1999/013626 WO1999065931A1 (en) 1998-06-17 1999-06-17 Non-enzymatic chemical amidation process

Publications (1)

Publication Number Publication Date
AU4688799A true AU4688799A (en) 2000-01-05

Family

ID=22218740

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46887/99A Abandoned AU4688799A (en) 1998-06-17 1999-06-17 Non-enzymatic chemical amidation process

Country Status (4)

Country Link
EP (1) EP1086121A4 (de)
AU (1) AU4688799A (de)
CA (1) CA2331330A1 (de)
WO (1) WO1999065931A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015068532A1 (ja) * 2013-11-05 2015-05-14 味の素株式会社 ペプチドヒドラジド、ペプチドアミド及びペプチドチオエステルの製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60194000A (ja) * 1984-03-14 1985-10-02 Amano Pharmaceut Co Ltd ペプチドアミドスルフエ−トエステル
ATE180491T1 (de) * 1993-02-19 1999-06-15 Hoffmann La Roche Racemisierungsfreie herstellung von amiden und peptiden in gegenwart katalytischer mengen einer n-hydroxy-verbindung
US5589364A (en) * 1994-07-29 1996-12-31 Magainin Pharmaceuticals Inc. Recombinant production of biologically active peptides and proteins

Also Published As

Publication number Publication date
WO1999065931A1 (en) 1999-12-23
EP1086121A1 (de) 2001-03-28
EP1086121A4 (de) 2001-12-12
CA2331330A1 (en) 1999-12-23
WO1999065931A9 (en) 2000-03-23

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted