EP1086121A4 - Nicht-enzymatische chemische amidierungsverfahren - Google Patents

Nicht-enzymatische chemische amidierungsverfahren

Info

Publication number
EP1086121A4
EP1086121A4 EP99930329A EP99930329A EP1086121A4 EP 1086121 A4 EP1086121 A4 EP 1086121A4 EP 99930329 A EP99930329 A EP 99930329A EP 99930329 A EP99930329 A EP 99930329A EP 1086121 A4 EP1086121 A4 EP 1086121A4
Authority
EP
European Patent Office
Prior art keywords
amidation process
enzymatic chemical
chemical amidation
enzymatic
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99930329A
Other languages
English (en)
French (fr)
Other versions
EP1086121A1 (de
Inventor
Stephen R Jones
Lincoln A Noecker
Binyamin Feibush
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Magainin Pharmaceuticals Inc
Original Assignee
Magainin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magainin Pharmaceuticals Inc filed Critical Magainin Pharmaceuticals Inc
Publication of EP1086121A1 publication Critical patent/EP1086121A1/de
Publication of EP1086121A4 publication Critical patent/EP1086121A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/124—Hydrazinolysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
EP99930329A 1998-06-17 1999-06-17 Nicht-enzymatische chemische amidierungsverfahren Withdrawn EP1086121A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8963598P 1998-06-17 1998-06-17
US89635P 1998-06-17
PCT/US1999/013626 WO1999065931A1 (en) 1998-06-17 1999-06-17 Non-enzymatic chemical amidation process

Publications (2)

Publication Number Publication Date
EP1086121A1 EP1086121A1 (de) 2001-03-28
EP1086121A4 true EP1086121A4 (de) 2001-12-12

Family

ID=22218740

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99930329A Withdrawn EP1086121A4 (de) 1998-06-17 1999-06-17 Nicht-enzymatische chemische amidierungsverfahren

Country Status (4)

Country Link
EP (1) EP1086121A4 (de)
AU (1) AU4688799A (de)
CA (1) CA2331330A1 (de)
WO (1) WO1999065931A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6493216B2 (ja) * 2013-11-05 2019-04-03 味の素株式会社 ペプチドヒドラジド、ペプチドアミド及びペプチドチオエステルの製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60194000A (ja) * 1984-03-14 1985-10-02 Amano Pharmaceut Co Ltd ペプチドアミドスルフエ−トエステル
EP0611774B1 (de) * 1993-02-19 1999-05-26 F. Hoffmann-La Roche Ag Racemisierungsfreie Herstellung von Amiden und Peptiden in Gegenwart katalytischer Mengen einer N-Hydroxy-Verbindung
US5589364A (en) * 1994-07-29 1996-12-31 Magainin Pharmaceuticals Inc. Recombinant production of biologically active peptides and proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9965931A1 *

Also Published As

Publication number Publication date
AU4688799A (en) 2000-01-05
WO1999065931A9 (en) 2000-03-23
CA2331330A1 (en) 1999-12-23
EP1086121A1 (de) 2001-03-28
WO1999065931A1 (en) 1999-12-23

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