AU461139B2 - Novel benzodiazepines and processes for their preparation - Google Patents

Novel benzodiazepines and processes for their preparation

Info

Publication number
AU461139B2
AU461139B2 AU44673/72A AU4467372A AU461139B2 AU 461139 B2 AU461139 B2 AU 461139B2 AU 44673/72 A AU44673/72 A AU 44673/72A AU 4467372 A AU4467372 A AU 4467372A AU 461139 B2 AU461139 B2 AU 461139B2
Authority
AU
Australia
Prior art keywords
processes
preparation
novel benzodiazepines
benzodiazepines
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU44673/72A
Other languages
English (en)
Other versions
AU4467372A (en
Inventor
JR. and ARTHUR RAYMOND HAUZE-DECEASED JACKSON BOLING HESTER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU4467372A publication Critical patent/AU4467372A/en
Application granted granted Critical
Publication of AU461139B2 publication Critical patent/AU461139B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU44673/72A 1971-08-04 1972-07-18 Novel benzodiazepines and processes for their preparation Expired AU461139B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16909171A 1971-08-04 1971-08-04
USUS169091 1971-08-04

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU82553/75A Division AU487137B2 (en) 1975-06-27 1975-06-27 Benzodiazepines and their preparation

Publications (2)

Publication Number Publication Date
AU4467372A AU4467372A (en) 1974-01-24
AU461139B2 true AU461139B2 (en) 1975-05-15

Family

ID=22614230

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44673/72A Expired AU461139B2 (en) 1971-08-04 1972-07-18 Novel benzodiazepines and processes for their preparation

Country Status (8)

Country Link
JP (3) JPS5714351B1 (fr)
AU (1) AU461139B2 (fr)
BE (1) BE787251A (fr)
CH (3) CH584206A5 (fr)
DE (1) DE2237592C2 (fr)
FR (1) FR2150732B1 (fr)
GB (4) GB1389437A (fr)
ZA (1) ZA724880B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917627A (en) * 1971-08-04 1975-11-04 Upjohn Co 6-Substituted 4H-imidazo{8 1,2-a{9 {8 1,4{9 benzodiazepines and process for their production
FR2183716A1 (en) * 1972-05-05 1973-12-21 Centre Etd Ind Pharma Substd-6-phenyl-4h-imidazo (1,2-a)-1,4-benzo diazepines - - tranquillisers anxiolytics,sedatives and muscle-relaxants
ZA755418B (en) * 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
US3910946A (en) * 1974-09-12 1975-10-07 Upjohn Co 4H-Imidazo{8 1,2-a{9 {8 1,4{9 benzodiazepines
JPS6015633B2 (ja) * 1974-11-06 1985-04-20 パーク・デービス・アンド・コンパニー 新規なジアゼピン化合物の製法
AU509371B2 (en) * 1975-08-07 1980-05-08 F. Hoffmann-La Roche Ag Diazepine Derivatives
US4118386A (en) * 1977-04-04 1978-10-03 Hoffmann-La Roche Inc. Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
EP0698015A1 (fr) * 1993-05-14 1996-02-28 Genentech, Inc. Preparation de n-cyanodithioimino-carbonates et de 3-mercapto-5-amino-1h-1,2,4-triazole
WO1996023790A1 (fr) * 1995-02-02 1996-08-08 F. Hoffmann-La Roche Ag Acetylimidazobenzodiazepines
US10266534B2 (en) 2014-06-26 2019-04-23 The Johns Hopkins University Peripherally restricted GABA positive allosteric modulators for the treatment of irritable bowel syndrome and other ailments of the peripheral nervous system
EP3535253A1 (fr) * 2016-11-01 2019-09-11 H. Hoffnabb-La Roche Ag 1,3-dihydro -1,4-benzodiazépine-2-thiones pour le traitement de maladies liées au snc
CN113717176B (zh) * 2021-10-09 2022-07-05 上海再启生物技术有限公司 一种制备瑞马唑仑的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987052A (en) * 1969-03-17 1976-10-19 The Upjohn Company 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines

Also Published As

Publication number Publication date
GB1389437A (en) 1975-04-03
JPS5547686A (en) 1980-04-04
DE2237592A1 (de) 1973-02-15
DE2237592C2 (de) 1985-08-14
AU4467372A (en) 1974-01-24
GB1389435A (en) 1975-04-03
BE787251A (fr) 1973-02-05
CH584206A5 (fr) 1977-01-31
GB1389434A (en) 1975-04-03
CH574444A5 (fr) 1976-04-15
GB1389436A (en) 1975-04-03
JPS5726667A (en) 1982-02-12
CH591488A5 (fr) 1977-09-30
JPS5732066B2 (fr) 1982-07-08
FR2150732B1 (fr) 1976-04-16
ZA724880B (en) 1973-06-27
FR2150732A1 (fr) 1973-04-13
JPS5714351B1 (fr) 1982-03-24
JPS5734277B2 (fr) 1982-07-22

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