AU4610472A - 2. 4-dihydro-2h-isoquinoline-1-thiones and process for preparing them - Google Patents
2. 4-dihydro-2h-isoquinoline-1-thiones and process for preparing themInfo
- Publication number
- AU4610472A AU4610472A AU46104/72A AU4610472A AU4610472A AU 4610472 A AU4610472 A AU 4610472A AU 46104/72 A AU46104/72 A AU 46104/72A AU 4610472 A AU4610472 A AU 4610472A AU 4610472 A AU4610472 A AU 4610472A
- Authority
- AU
- Australia
- Prior art keywords
- thiones
- isoquinoline
- dihydro
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2143745A DE2143745A1 (de) | 1971-09-01 | 1971-09-01 | 3,4-dihydro-2h-isochinolin-1-thione und verfahren zu ihrer herstellung |
| DEDE8214374 | 1971-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU4610472A true AU4610472A (en) | 1974-03-07 |
Family
ID=5818354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU46104/72A Expired AU4610472A (en) | 1971-09-01 | 1972-08-30 | 2. 4-dihydro-2h-isoquinoline-1-thiones and process for preparing them |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS4834885A (enExample) |
| AU (1) | AU4610472A (enExample) |
| BE (1) | BE788321A (enExample) |
| CA (1) | CA972755A (enExample) |
| DD (1) | DD102148A5 (enExample) |
| DE (1) | DE2143745A1 (enExample) |
| ES (1) | ES406134A1 (enExample) |
| FR (1) | FR2151044A1 (enExample) |
| IL (1) | IL40250A0 (enExample) |
| NL (1) | NL7211627A (enExample) |
| ZA (1) | ZA725997B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8475842B2 (en) | 2008-10-07 | 2013-07-02 | Astrazeneca Ab | Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL89997A0 (en) * | 1988-04-25 | 1989-12-15 | Lilly Co Eli | Propanamine derivatives |
| US5177075A (en) * | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
| CA1334969C (en) * | 1988-08-19 | 1995-03-28 | Mark James Suto | Substituted dihydroisoquinoline and phthalazine derivatives as potentiators of the lethal effects of radiation and certain chemotherapeutic agents, selected compounds, analogs andprocess |
| US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| DE60218458T2 (de) * | 2001-05-08 | 2007-11-15 | Kudos Pharmaceuticals Ltd. | Isochinolinon derivate als parp inhibitoren |
| EP1501822B1 (en) | 2002-04-30 | 2010-12-15 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
| GB0419072D0 (en) | 2004-08-26 | 2004-09-29 | Kudos Pharm Ltd | Phthalazinone derivatives |
| GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
| RU2010108008A (ru) | 2007-09-14 | 2011-10-20 | Астразенека Аб (Se) | Фталазиноновые производные |
| RU2487868C2 (ru) | 2007-10-17 | 2013-07-20 | Кудос Фармасеутикалс Лимитед | 4-[3-(4-циклопропанкарбонил-пиперазин-1-карбонил)-4-фтор-бензил]-2н-фталазин-1-он |
| UY31603A1 (es) | 2008-01-23 | 2009-08-31 | Derivados de ftalazinona |
-
1971
- 1971-09-01 DE DE2143745A patent/DE2143745A1/de active Pending
-
1972
- 1972-08-16 DD DD165084A patent/DD102148A5/xx unknown
- 1972-08-25 NL NL7211627A patent/NL7211627A/xx unknown
- 1972-08-25 CA CA150,238A patent/CA972755A/en not_active Expired
- 1972-08-26 ES ES406134A patent/ES406134A1/es not_active Expired
- 1972-08-29 IL IL40250A patent/IL40250A0/xx unknown
- 1972-08-30 AU AU46104/72A patent/AU4610472A/en not_active Expired
- 1972-08-31 ZA ZA725997A patent/ZA725997B/xx unknown
- 1972-08-31 FR FR7230951A patent/FR2151044A1/fr not_active Withdrawn
- 1972-09-01 JP JP47087839A patent/JPS4834885A/ja active Pending
- 1972-09-01 BE BE788321D patent/BE788321A/xx unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8475842B2 (en) | 2008-10-07 | 2013-07-02 | Astrazeneca Ab | Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
| US11633396B2 (en) | 2008-10-07 | 2023-04-25 | Kudos Pharmaceuticals Limited | Immediate release pharmaceutical formulation of 4-[3-(4- cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H- phthalazin-1-one |
| US11975001B2 (en) | 2008-10-07 | 2024-05-07 | Kudos Pharmaceuticals Limited | Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
| US12048695B2 (en) | 2008-10-07 | 2024-07-30 | Kudos Pharmaceuticals Limited | Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
| US12144810B1 (en) | 2008-10-07 | 2024-11-19 | Kudos Pharmaceuticals Limited | Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
| US12178816B2 (en) | 2008-10-07 | 2024-12-31 | Kudos Pharmaceuticals Limited | Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2143745A1 (de) | 1973-03-08 |
| IL40250A0 (en) | 1972-10-29 |
| ES406134A1 (es) | 1975-08-01 |
| BE788321A (fr) | 1973-03-01 |
| ZA725997B (en) | 1973-07-25 |
| CA972755A (en) | 1975-08-12 |
| DD102148A5 (enExample) | 1973-12-05 |
| JPS4834885A (enExample) | 1973-05-22 |
| NL7211627A (enExample) | 1973-03-05 |
| FR2151044A1 (en) | 1973-04-13 |
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