ZA725997B - 3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing them - Google Patents

3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing them

Info

Publication number
ZA725997B
ZA725997B ZA725997A ZA725997A ZA725997B ZA 725997 B ZA725997 B ZA 725997B ZA 725997 A ZA725997 A ZA 725997A ZA 725997 A ZA725997 A ZA 725997A ZA 725997 B ZA725997 B ZA 725997B
Authority
ZA
South Africa
Prior art keywords
thiones
isoquinoline
dihydro
preparing
Prior art date
Application number
ZA725997A
Other languages
English (en)
Inventor
R Kunstann
E Granzer
G Seidl
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA725997B publication Critical patent/ZA725997B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA725997A 1971-09-01 1972-08-31 3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing them ZA725997B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2143745A DE2143745A1 (de) 1971-09-01 1971-09-01 3,4-dihydro-2h-isochinolin-1-thione und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA725997B true ZA725997B (en) 1973-07-25

Family

ID=5818354

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA725997A ZA725997B (en) 1971-09-01 1972-08-31 3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing them

Country Status (11)

Country Link
JP (1) JPS4834885A (xx)
AU (1) AU4610472A (xx)
BE (1) BE788321A (xx)
CA (1) CA972755A (xx)
DD (1) DD102148A5 (xx)
DE (1) DE2143745A1 (xx)
ES (1) ES406134A1 (xx)
FR (1) FR2151044A1 (xx)
IL (1) IL40250A0 (xx)
NL (1) NL7211627A (xx)
ZA (1) ZA725997B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89997A0 (en) * 1988-04-25 1989-12-15 Lilly Co Eli Propanamine derivatives
US5177075A (en) * 1988-08-19 1993-01-05 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
JP2786896B2 (ja) * 1988-08-19 1998-08-13 ワーナー―ランバート・コンパニー 置換されたジヒドロイソキノリノンおよび関連化合物
US7151102B2 (en) 2000-10-30 2006-12-19 Kudos Pharmaceuticals Limited Phthalazinone derivatives
WO2002090334A1 (en) * 2001-05-08 2002-11-14 Kudos Pharmaceuticals Limited Isoquinolinone derivatives as parp inhibitors
EP1501822B1 (en) 2002-04-30 2010-12-15 Kudos Pharmaceuticals Limited Phthalazinone derivatives
GB0305681D0 (en) 2003-03-12 2003-04-16 Kudos Pharm Ltd Phthalazinone derivatives
US7449464B2 (en) 2003-03-12 2008-11-11 Kudos Pharmaceuticals Limited Phthalazinone derivatives
GB0419072D0 (en) 2004-08-26 2004-09-29 Kudos Pharm Ltd Phthalazinone derivatives
GB0521373D0 (en) 2005-10-20 2005-11-30 Kudos Pharm Ltd Pthalazinone derivatives
MX2010002749A (es) 2007-09-14 2010-06-25 Astrazeneca Ab Derivados de ftalazinona.
BRPI0817537B1 (pt) 2007-10-17 2022-04-05 Kudos Pharmaceuticals Limited 4-[3-(4-ciclopropanocarbonil-piperazina-1-carbonil)-4-fluoro-benzil]-2h-ftalazin-1-ona, método para obtê-lo, composição farmacêutica compreendendo o mesmo, bem como usos terapêuticos do dito composto
UY31603A1 (es) 2008-01-23 2009-08-31 Derivados de ftalazinona
WO2010041051A1 (en) 2008-10-07 2010-04-15 Astrazeneca Uk Limited Pharmaceutical formulation 514

Also Published As

Publication number Publication date
FR2151044A1 (en) 1973-04-13
DE2143745A1 (de) 1973-03-08
BE788321A (fr) 1973-03-01
DD102148A5 (xx) 1973-12-05
AU4610472A (en) 1974-03-07
ES406134A1 (es) 1975-08-01
CA972755A (en) 1975-08-12
IL40250A0 (en) 1972-10-29
NL7211627A (xx) 1973-03-05
JPS4834885A (xx) 1973-05-22

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