ZA725997B - 3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing them - Google Patents
3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing themInfo
- Publication number
- ZA725997B ZA725997B ZA725997A ZA725997A ZA725997B ZA 725997 B ZA725997 B ZA 725997B ZA 725997 A ZA725997 A ZA 725997A ZA 725997 A ZA725997 A ZA 725997A ZA 725997 B ZA725997 B ZA 725997B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiones
- isoquinoline
- dihydro
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2143745A DE2143745A1 (en) | 1971-09-01 | 1971-09-01 | 3,4-DIHYDRO-2H-ISOCHINOLIN-1-THIONE AND THE METHOD FOR MANUFACTURING IT |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA725997B true ZA725997B (en) | 1973-07-25 |
Family
ID=5818354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA725997A ZA725997B (en) | 1971-09-01 | 1972-08-31 | 3,4-dihydro 2h-isoquinoline-1-thiones and process for preparing them |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS4834885A (en) |
AU (1) | AU4610472A (en) |
BE (1) | BE788321A (en) |
CA (1) | CA972755A (en) |
DD (1) | DD102148A5 (en) |
DE (1) | DE2143745A1 (en) |
ES (1) | ES406134A1 (en) |
FR (1) | FR2151044A1 (en) |
IL (1) | IL40250A0 (en) |
NL (1) | NL7211627A (en) |
ZA (1) | ZA725997B (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL89997A0 (en) * | 1988-04-25 | 1989-12-15 | Lilly Co Eli | Propanamine derivatives |
EP0355750B1 (en) * | 1988-08-19 | 1995-01-25 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
US5177075A (en) * | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
ATE355278T1 (en) | 2001-05-08 | 2006-03-15 | Kudos Pharm Ltd | ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS |
CA2482806A1 (en) | 2002-04-30 | 2003-11-13 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
GB0419072D0 (en) | 2004-08-26 | 2004-09-29 | Kudos Pharm Ltd | Phthalazinone derivatives |
GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
MX2010002749A (en) | 2007-09-14 | 2010-06-25 | Astrazeneca Ab | Phthalazinone derivatives. |
CA2702429A1 (en) | 2007-10-17 | 2009-04-23 | Kudos Pharmaceuticals Limited | Crystalline form l 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthalazin-1-one |
AR070221A1 (en) | 2008-01-23 | 2010-03-25 | Astrazeneca Ab | DERIVATIVES OF FTALAZINONA POLYMERASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USES OF THE SAME TO PREVENT AND / OR TREAT CANCERIGENE TUMORS, ISCHEMICAL INJURIES AND OTHER ASSOCIATED DISEASES. |
EA020783B1 (en) | 2008-10-07 | 2015-01-30 | Астразенека Юк Лимитед | Pharmaceutical formulation comprising 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2h-phthalazin-1-one and copovidone |
-
1971
- 1971-09-01 DE DE2143745A patent/DE2143745A1/en active Pending
-
1972
- 1972-08-16 DD DD165084A patent/DD102148A5/xx unknown
- 1972-08-25 CA CA150,238A patent/CA972755A/en not_active Expired
- 1972-08-25 NL NL7211627A patent/NL7211627A/xx unknown
- 1972-08-26 ES ES406134A patent/ES406134A1/en not_active Expired
- 1972-08-29 IL IL40250A patent/IL40250A0/en unknown
- 1972-08-30 AU AU46104/72A patent/AU4610472A/en not_active Expired
- 1972-08-31 ZA ZA725997A patent/ZA725997B/en unknown
- 1972-08-31 FR FR7230951A patent/FR2151044A1/en not_active Withdrawn
- 1972-09-01 JP JP47087839A patent/JPS4834885A/ja active Pending
- 1972-09-01 BE BE788321D patent/BE788321A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE788321A (en) | 1973-03-01 |
DE2143745A1 (en) | 1973-03-08 |
AU4610472A (en) | 1974-03-07 |
JPS4834885A (en) | 1973-05-22 |
NL7211627A (en) | 1973-03-05 |
CA972755A (en) | 1975-08-12 |
IL40250A0 (en) | 1972-10-29 |
DD102148A5 (en) | 1973-12-05 |
ES406134A1 (en) | 1975-08-01 |
FR2151044A1 (en) | 1973-04-13 |
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