AU459272B2 - New 2, 2'-methylenediphenols, compositions based theron and methods for preparing both - Google Patents

New 2, 2'-methylenediphenols, compositions based theron and methods for preparing both

Info

Publication number
AU459272B2
AU459272B2 AU40850/72A AU4085072A AU459272B2 AU 459272 B2 AU459272 B2 AU 459272B2 AU 40850/72 A AU40850/72 A AU 40850/72A AU 4085072 A AU4085072 A AU 4085072A AU 459272 B2 AU459272 B2 AU 459272B2
Authority
AU
Australia
Prior art keywords
methylenediphenols
preparing
new
methods
compositions based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU40850/72A
Other languages
English (en)
Other versions
AU4085072A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACF Chemiefarma NV
Original Assignee
ACF Chemiefarma NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACF Chemiefarma NV filed Critical ACF Chemiefarma NV
Publication of AU4085072A publication Critical patent/AU4085072A/en
Application granted granted Critical
Publication of AU459272B2 publication Critical patent/AU459272B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/26Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU40850/72A 1971-04-09 1972-04-06 New 2, 2'-methylenediphenols, compositions based theron and methods for preparing both Expired AU459272B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7104839.A NL167151C (nl) 1971-04-09 1971-04-09 Werkwijze ter bereiding van geneesmiddelen met anti-parasitaire werking op basis van halogeen bevatten- de 2,2'-methyleendifenolderivaten, alsmede werkwijze ter bereiding van deze geneeskrachtige verbindingen.

Publications (2)

Publication Number Publication Date
AU4085072A AU4085072A (en) 1973-10-11
AU459272B2 true AU459272B2 (en) 1975-03-05

Family

ID=19812895

Family Applications (1)

Application Number Title Priority Date Filing Date
AU40850/72A Expired AU459272B2 (en) 1971-04-09 1972-04-06 New 2, 2'-methylenediphenols, compositions based theron and methods for preparing both

Country Status (19)

Country Link
US (1) US3884906A (cg-RX-API-DMAC10.html)
JP (2) JPS5525177B1 (cg-RX-API-DMAC10.html)
AR (2) AR194587A1 (cg-RX-API-DMAC10.html)
AU (1) AU459272B2 (cg-RX-API-DMAC10.html)
BE (1) BE781674A (cg-RX-API-DMAC10.html)
CH (2) CH575372A5 (cg-RX-API-DMAC10.html)
DE (1) DE2215409C3 (cg-RX-API-DMAC10.html)
DK (1) DK143227C (cg-RX-API-DMAC10.html)
ES (1) ES401501A1 (cg-RX-API-DMAC10.html)
FR (1) FR2132788B1 (cg-RX-API-DMAC10.html)
GB (1) GB1346266A (cg-RX-API-DMAC10.html)
HU (1) HU165790B (cg-RX-API-DMAC10.html)
IE (1) IE36209B1 (cg-RX-API-DMAC10.html)
IL (1) IL39108A (cg-RX-API-DMAC10.html)
NL (1) NL167151C (cg-RX-API-DMAC10.html)
PH (2) PH15268A (cg-RX-API-DMAC10.html)
SE (1) SE389331B (cg-RX-API-DMAC10.html)
SU (1) SU580828A3 (cg-RX-API-DMAC10.html)
ZA (1) ZA722331B (cg-RX-API-DMAC10.html)

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AU4101678A (en) * 1977-11-08 1980-05-01 Ici Australia Ltd Process for killing parasites
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
US6403652B1 (en) 2000-06-30 2002-06-11 Colgate-Palmolive Company Method and composition
IL218714A (en) * 2004-03-16 2013-02-28 Boehringer Ingelheim Int Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof
UA91546C2 (uk) * 2005-05-03 2010-08-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
US7772191B2 (en) 2005-05-10 2010-08-10 Boehringer Ingelheim International Gmbh Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
PE20080697A1 (es) * 2006-05-03 2008-08-05 Boehringer Ingelheim Int Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
CL2008002427A1 (es) * 2007-08-16 2009-09-11 Boehringer Ingelheim Int Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
WO2009068617A1 (en) * 2007-11-30 2009-06-04 Boehringer Ingelheim International Gmbh 1, 5-dihydro-pyrazolo (3, 4-d) pyrimidin-4-one derivatives and their use as pde9a modulators for the teatment of cns disorders
UA105362C2 (en) * 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
MX2011002340A (es) 2008-09-08 2011-04-04 Boehringer Ingelheim Int Pirazolopirimidinas y su uso para el tratamiento de trastornos del snc.
JP5685550B2 (ja) 2009-02-13 2015-03-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Sglt2阻害剤、dpp−iv阻害剤、更に必要により抗糖尿病薬を含む医薬組成物及びその使用
HRP20240365T1 (hr) * 2009-02-13 2024-06-07 Boehringer Ingelheim International Gmbh Farmaceutski pripravak koji sadrži derivate glukopiranozil difenilmetana, njegov farmaceutski oblik za doziranje, postupak za njihovu proizvodnju i njihove uporabe za poboljšanu regulaciju glikemije kod pacijenta
MX344264B (es) 2009-02-13 2016-12-09 Boehringer Ingelheim Int Gmbh * Inhibidor de sglt-2 para el tratamiento de diabetes mellitus tipo 1, diabetes mellitus tipo 2, tolerancia deteriorada a la glucosa o hiperglucemia.
BRPI1011533A2 (pt) * 2009-03-31 2016-03-29 Boehringer Ingelheim Int derivados de 1-heterocicil-1 5- diidro-pirazolo [3,4--d] pirimidin-4-ona e seu uso como moduladores de pde9a.
TW201118099A (en) * 2009-08-12 2011-06-01 Boehringer Ingelheim Int New compounds for the treatment of CNS disorders
AU2010303123B2 (en) * 2009-09-30 2014-02-27 Boehringer Ingelheim International Gmbh Method for the preparation of a crystalline form of 1-chloro-4- (Beta-D-glucopyranos-1-yl)-2-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)benzene
HUE026133T2 (en) 2009-09-30 2016-05-30 Boehringer Ingelheim Int Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives
UY32919A (es) * 2009-10-02 2011-04-29 Boehringer Ingelheim Int Composición farmacéutica, forma de dosificación farmacéutica, procedimiento para su preparación, mé todos para su tratamiento y sus usos
AP2012006631A0 (en) 2010-08-12 2012-12-31 Boehringer Ingelheim Int 6-Cycloalkyl-1, 5-dihydro-pyrazolo[3,4-D] pyrimidin-4-one derivatives and their use as PDE9A inhibitors
US8809345B2 (en) 2011-02-15 2014-08-19 Boehringer Ingelheim International Gmbh 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
UY33937A (es) 2011-03-07 2012-09-28 Boehringer Ingelheim Int Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
US9192617B2 (en) 2012-03-20 2015-11-24 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
HK1215398A1 (zh) 2013-04-05 2016-08-26 勃林格殷格翰国际有限公司 依帕列净的治疗用途
US11813275B2 (en) 2013-04-05 2023-11-14 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US20140303097A1 (en) 2013-04-05 2014-10-09 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
CA2812519A1 (en) 2013-04-05 2014-10-05 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
PT2986304T (pt) 2013-04-18 2022-02-25 Boehringer Ingelheim Int Composição farmacêutica, métodos para o tratamento e suas utilizações
MA46742A (fr) 2016-11-10 2019-09-18 Boehringer Ingelheim Int Composition pharmaceutique, méthodes de traitement et leurs utilisations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2544826A (en) * 1945-05-08 1951-03-13 Dow Chemical Co Anthelmintic feed composition
US2615052A (en) * 1950-06-23 1952-10-21 Allied Lab Inc 2,2'-methylenebis(4-chloro-6-nitrophenol) and a method for its production
US2739941A (en) * 1952-09-13 1956-03-27 Gen Aniline & Film Corp Germicidal soap composition
NL283922A (cg-RX-API-DMAC10.html) * 1962-10-03

Also Published As

Publication number Publication date
DK143227B (da) 1981-07-27
PH14191A (en) 1981-03-26
DE2215409C3 (de) 1980-10-09
NL167151C (nl) 1981-11-16
AU4085072A (en) 1973-10-11
AR193590A1 (es) 1973-04-30
SU580828A3 (ru) 1977-11-15
BE781674A (fr) 1972-10-05
SE389331B (sv) 1976-11-01
ZA722331B (en) 1973-01-31
JPS5525177B1 (cg-RX-API-DMAC10.html) 1980-07-04
NL167151B (nl) 1981-06-16
DE2215409A1 (de) 1973-01-25
DK143227C (da) 1981-11-30
DE2215409B2 (de) 1980-02-14
HU165790B (cg-RX-API-DMAC10.html) 1974-11-28
IL39108A (en) 1976-04-30
NL7104839A (cg-RX-API-DMAC10.html) 1972-10-11
CH575372A5 (cg-RX-API-DMAC10.html) 1976-05-14
IE36209L (en) 1972-10-09
ES401501A1 (es) 1975-02-16
JPS5950645B2 (ja) 1984-12-10
GB1346266A (en) 1974-02-06
FR2132788B1 (cg-RX-API-DMAC10.html) 1976-05-14
IE36209B1 (en) 1976-09-15
AR194587A1 (es) 1973-07-31
PH15268A (en) 1982-11-02
FR2132788A1 (cg-RX-API-DMAC10.html) 1972-11-24
JPS557256A (en) 1980-01-19
IL39108A0 (en) 1972-05-30
CH586182A5 (cg-RX-API-DMAC10.html) 1977-03-31
US3884906A (en) 1975-05-20

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