AU3307384A - Preparation of compounds containing carboxamide groups - Google Patents

Preparation of compounds containing carboxamide groups

Info

Publication number
AU3307384A
AU3307384A AU33073/84A AU3307384A AU3307384A AU 3307384 A AU3307384 A AU 3307384A AU 33073/84 A AU33073/84 A AU 33073/84A AU 3307384 A AU3307384 A AU 3307384A AU 3307384 A AU3307384 A AU 3307384A
Authority
AU
Australia
Prior art keywords
preparation
reaction
compounds containing
compounds
carboxamide groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU33073/84A
Other versions
AU570724B2 (en
Inventor
Volker Teetz
Hans Wissmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Publication of AU3307384A publication Critical patent/AU3307384A/en
Application granted granted Critical
Publication of AU570724B2 publication Critical patent/AU570724B2/en
Assigned to AVENTIS PHARMA DEUTSCHLAND GMBH reassignment AVENTIS PHARMA DEUTSCHLAND GMBH Alteration of Name(s) in Register under S187 Assignors: HOECHST A.G.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus

Abstract

1. A process for the preparation of compounds containing carboxamide groups by reaction of compounds which contain a carboxyl group, in the presence of dialkylphosphinic anhydrides, with compounds which contain a free amino group, which comprises maintaining the hydrogen ion concentration in the reaction mixture at an almost constant value in a range of 10**-5 to 10**-10 (mol/l) during the reaction and, after the reaction is complete, eliminating radicals which have, where appropriate, been introduced to protect other functional groups.
AU33073/84A 1983-09-16 1984-09-14 Preparation of compounds containing carboxamide groups Expired AU570724B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833333456 DE3333456A1 (en) 1983-09-16 1983-09-16 METHOD FOR PRODUCING COMPOUNDS CONTAINING CARBONIC ACID AMIDE, IN PARTICULAR PEPTIDES
DE3333456 1983-09-16

Publications (2)

Publication Number Publication Date
AU3307384A true AU3307384A (en) 1985-03-21
AU570724B2 AU570724B2 (en) 1988-03-24

Family

ID=6209237

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33073/84A Expired AU570724B2 (en) 1983-09-16 1984-09-14 Preparation of compounds containing carboxamide groups

Country Status (13)

Country Link
EP (1) EP0135183B1 (en)
JP (1) JPS6084249A (en)
AT (1) ATE33251T1 (en)
AU (1) AU570724B2 (en)
CA (1) CA1285698C (en)
DE (2) DE3333456A1 (en)
DK (1) DK160041C (en)
ES (1) ES535919A0 (en)
GR (1) GR80370B (en)
HU (1) HU189936B (en)
IE (1) IE58082B1 (en)
IL (1) IL72943A (en)
PT (1) PT79195B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575585B2 (en) * 1983-09-16 1988-08-04 Aventis Pharma Deutschland Gmbh Preparation of n-alkylated dipeptides
AU576782B2 (en) * 1983-09-16 1988-09-08 Aventis Pharma Deutschland Gmbh Preparation of n-alkylated dipeptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901843A1 (en) * 1979-01-18 1980-07-31 Hoechst Ag METHOD FOR PRODUCING CARBONIC ACID AMIDES AND PEPTIDES
DE3101427A1 (en) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "METHOD FOR PRODUCING COMPOUNDS CONTAINING CARBONIC ACID AMIDE, IN PARTICULAR PEPTIDES"
DE3333455A1 (en) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS
DE3333454A1 (en) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575585B2 (en) * 1983-09-16 1988-08-04 Aventis Pharma Deutschland Gmbh Preparation of n-alkylated dipeptides
AU576782B2 (en) * 1983-09-16 1988-09-08 Aventis Pharma Deutschland Gmbh Preparation of n-alkylated dipeptides

Also Published As

Publication number Publication date
DK440184A (en) 1985-03-17
HUT36083A (en) 1985-08-28
EP0135183A3 (en) 1986-03-05
IE58082B1 (en) 1993-06-30
IL72943A0 (en) 1984-12-31
PT79195A (en) 1984-10-01
DK160041C (en) 1991-06-10
GR80370B (en) 1985-01-11
AU570724B2 (en) 1988-03-24
IL72943A (en) 1988-07-31
ATE33251T1 (en) 1988-04-15
ES8505939A1 (en) 1985-06-16
JPS6084249A (en) 1985-05-13
DK440184D0 (en) 1984-09-14
DE3333456A1 (en) 1985-04-11
IE842352L (en) 1985-03-16
ES535919A0 (en) 1985-06-16
HU189936B (en) 1986-08-28
DK160041B (en) 1991-01-21
CA1285698C (en) 1991-07-02
DE3470162D1 (en) 1988-05-05
EP0135183A2 (en) 1985-03-27
PT79195B (en) 1986-09-10
EP0135183B1 (en) 1988-03-30
JPH0417177B2 (en) 1992-03-25

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Legal Events

Date Code Title Description
PC Assignment registered

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH

Free format text: FORMER OWNER WAS: HOECHST A.G.