DK160041C - PROCEDURE FOR THE PREPARATION OF CARBOXYLIC ACIDAMIDE GROUP, COMPOUNDS OF PEPTIDES - Google Patents
PROCEDURE FOR THE PREPARATION OF CARBOXYLIC ACIDAMIDE GROUP, COMPOUNDS OF PEPTIDESInfo
- Publication number
- DK160041C DK160041C DK440184A DK440184A DK160041C DK 160041 C DK160041 C DK 160041C DK 440184 A DK440184 A DK 440184A DK 440184 A DK440184 A DK 440184A DK 160041 C DK160041 C DK 160041C
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- preparation
- reaction
- peptides
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
- C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1. A process for the preparation of compounds containing carboxamide groups by reaction of compounds which contain a carboxyl group, in the presence of dialkylphosphinic anhydrides, with compounds which contain a free amino group, which comprises maintaining the hydrogen ion concentration in the reaction mixture at an almost constant value in a range of 10**-5 to 10**-10 (mol/l) during the reaction and, after the reaction is complete, eliminating radicals which have, where appropriate, been introduced to protect other functional groups.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3333456 | 1983-09-16 | ||
| DE19833333456 DE3333456A1 (en) | 1983-09-16 | 1983-09-16 | METHOD FOR PRODUCING COMPOUNDS CONTAINING CARBONIC ACID AMIDE, IN PARTICULAR PEPTIDES |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK440184D0 DK440184D0 (en) | 1984-09-14 |
| DK440184A DK440184A (en) | 1985-03-17 |
| DK160041B DK160041B (en) | 1991-01-21 |
| DK160041C true DK160041C (en) | 1991-06-10 |
Family
ID=6209237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK440184A DK160041C (en) | 1983-09-16 | 1984-09-14 | PROCEDURE FOR THE PREPARATION OF CARBOXYLIC ACIDAMIDE GROUP, COMPOUNDS OF PEPTIDES |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0135183B1 (en) |
| JP (1) | JPS6084249A (en) |
| AT (1) | ATE33251T1 (en) |
| AU (1) | AU570724B2 (en) |
| CA (1) | CA1285698C (en) |
| DE (2) | DE3333456A1 (en) |
| DK (1) | DK160041C (en) |
| ES (1) | ES535919A0 (en) |
| GR (1) | GR80370B (en) |
| HU (1) | HU189936B (en) |
| IE (1) | IE58082B1 (en) |
| IL (1) | IL72943A (en) |
| PT (1) | PT79195B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3333455A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
| DE3333454A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2901843A1 (en) * | 1979-01-18 | 1980-07-31 | Hoechst Ag | METHOD FOR PRODUCING CARBONIC ACID AMIDES AND PEPTIDES |
| DE3101427A1 (en) * | 1981-01-17 | 1982-09-02 | Hoechst Ag, 6000 Frankfurt | "METHOD FOR PRODUCING COMPOUNDS CONTAINING CARBONIC ACID AMIDE, IN PARTICULAR PEPTIDES" |
| DE3333455A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
| DE3333454A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
-
1983
- 1983-09-16 DE DE19833333456 patent/DE3333456A1/en not_active Withdrawn
-
1984
- 1984-09-07 AT AT84110679T patent/ATE33251T1/en not_active IP Right Cessation
- 1984-09-07 EP EP84110679A patent/EP0135183B1/en not_active Expired
- 1984-09-07 DE DE8484110679T patent/DE3470162D1/en not_active Expired
- 1984-09-10 HU HU843418A patent/HU189936B/en unknown
- 1984-09-13 PT PT79195A patent/PT79195B/en active IP Right Revival
- 1984-09-13 CA CA000463073A patent/CA1285698C/en not_active Expired - Lifetime
- 1984-09-14 DK DK440184A patent/DK160041C/en not_active IP Right Cessation
- 1984-09-14 AU AU33073/84A patent/AU570724B2/en not_active Expired
- 1984-09-14 IE IE235284A patent/IE58082B1/en not_active IP Right Cessation
- 1984-09-14 JP JP59191870A patent/JPS6084249A/en active Granted
- 1984-09-14 GR GR80370A patent/GR80370B/en unknown
- 1984-09-14 ES ES535919A patent/ES535919A0/en active Granted
- 1984-09-14 IL IL72943A patent/IL72943A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3470162D1 (en) | 1988-05-05 |
| ES8505939A1 (en) | 1985-06-16 |
| GR80370B (en) | 1985-01-11 |
| EP0135183A2 (en) | 1985-03-27 |
| EP0135183B1 (en) | 1988-03-30 |
| ES535919A0 (en) | 1985-06-16 |
| PT79195A (en) | 1984-10-01 |
| HU189936B (en) | 1986-08-28 |
| AU3307384A (en) | 1985-03-21 |
| DK160041B (en) | 1991-01-21 |
| ATE33251T1 (en) | 1988-04-15 |
| AU570724B2 (en) | 1988-03-24 |
| EP0135183A3 (en) | 1986-03-05 |
| IL72943A (en) | 1988-07-31 |
| HUT36083A (en) | 1985-08-28 |
| PT79195B (en) | 1986-09-10 |
| DE3333456A1 (en) | 1985-04-11 |
| JPH0417177B2 (en) | 1992-03-25 |
| JPS6084249A (en) | 1985-05-13 |
| IE842352L (en) | 1985-03-16 |
| IE58082B1 (en) | 1993-06-30 |
| CA1285698C (en) | 1991-07-02 |
| DK440184D0 (en) | 1984-09-14 |
| IL72943A0 (en) | 1984-12-31 |
| DK440184A (en) | 1985-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |