AU2412595A - Multirepresentation of a peptide analogue of the dppiv substrate, especially of the kpr type, to inhibit the entry of hiv in cells - Google Patents

Multirepresentation of a peptide analogue of the dppiv substrate, especially of the kpr type, to inhibit the entry of hiv in cells

Info

Publication number
AU2412595A
AU2412595A AU24125/95A AU2412595A AU2412595A AU 2412595 A AU2412595 A AU 2412595A AU 24125/95 A AU24125/95 A AU 24125/95A AU 2412595 A AU2412595 A AU 2412595A AU 2412595 A AU2412595 A AU 2412595A
Authority
AU
Australia
Prior art keywords
multirepresentation
kpr
hiv
inhibit
entry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU24125/95A
Other languages
English (en)
Inventor
Jean-Paul Briand
Christian Callebaut
Gilles Guichard
Ara Hovanessian
Etienne Jacotot
Bernard Krust
Sylviane Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of AU2412595A publication Critical patent/AU2412595A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU24125/95A 1994-04-22 1995-04-21 Multirepresentation of a peptide analogue of the dppiv substrate, especially of the kpr type, to inhibit the entry of hiv in cells Abandoned AU2412595A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9404895A FR2719049B1 (fr) 1994-04-22 1994-04-22 Multireprésentation d'un analogue peptidique du substrat de la DPPIV, notamment de type KPR, afin d'inhiber l'entrée du HIV dans les cellules.
FR9404895 1994-04-22
PCT/FR1995/000528 WO1995029190A1 (fr) 1994-04-22 1995-04-21 Multirepresentation d'un analogue peptidique du substrat de la dppiv, notamment de type kpr, afin d'inhiber l'entree du hiv dans les cellules

Publications (1)

Publication Number Publication Date
AU2412595A true AU2412595A (en) 1995-11-16

Family

ID=9462438

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24125/95A Abandoned AU2412595A (en) 1994-04-22 1995-04-21 Multirepresentation of a peptide analogue of the dppiv substrate, especially of the kpr type, to inhibit the entry of hiv in cells

Country Status (6)

Country Link
EP (1) EP0756603A1 (fr)
JP (1) JPH10502337A (fr)
AU (1) AU2412595A (fr)
CA (1) CA2188470A1 (fr)
FR (1) FR2719049B1 (fr)
WO (1) WO1995029190A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825169B1 (en) 1991-10-22 2004-11-30 Trustees Of Tufts College Inhibitors of dipeptidyl-aminopeptidase type IV
US5965532A (en) 1996-06-28 1999-10-12 Trustees Of Tufts College Multivalent compounds for crosslinking receptors and uses thereof
US6011155A (en) * 1996-11-07 2000-01-04 Novartis Ag N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
CA2284084A1 (fr) * 1997-03-12 1998-09-17 Institut Pasteur Recepteur membranaire pour retrovirus de vih, utilisations therapeutiques et diagnostiques
US6100234A (en) * 1997-05-07 2000-08-08 Tufts University Treatment of HIV
US6040145A (en) 1997-05-07 2000-03-21 Tufts University Potentiation of the immune response
ES2285785T3 (es) 1997-09-29 2007-11-16 Point Therapeutics, Inc. Estimulacion de celulas hematopoyeticas in vitro.
MY132924A (en) 1998-05-04 2007-10-31 Point Therapeutics Inc Hematopoietic stimulation
WO1999062914A1 (fr) 1998-06-05 1999-12-09 Point Therapeutics, Inc. Composes cycliques de boroproline
CO5150173A1 (es) * 1998-12-10 2002-04-29 Novartis Ag Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
US6110949A (en) * 1999-06-24 2000-08-29 Novartis Ag N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
US6172081B1 (en) 1999-06-24 2001-01-09 Novartis Ag Tetrahydroisoquinoline 3-carboxamide derivatives
US6617340B1 (en) 1999-07-29 2003-09-09 Novartis Ag N-(substituted glycyl)-pyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
ATE374181T1 (de) 2001-06-27 2007-10-15 Smithkline Beecham Corp Fluorpyrrolidine als dipeptidylpeptidaseinhibitoren
EP1881003A1 (fr) * 2005-04-22 2008-01-23 Japan Crown Cork Co. Ltd. Composé ayant un résidu d'acide aminé ou un résidu de peptide et procédé servant à produire celui-ci
US20090133747A1 (en) * 2005-05-23 2009-05-28 CREDIA JAPAN CO., LTD. ( A juridical person under the laws of Japan) Compound having photosensitization activity, photoelectrode, and photosensitization-type solar cell
WO2007061077A1 (fr) * 2005-11-25 2007-05-31 Credia Japan Co., Ltd. Vehicule pour utilisation dans l'introduction d'acide nucleique, kit pour utilisation dans l'introduction d'acide nucleique, et procede pour l'introduction d'acide nucleique dans une cellule
FR2900341B1 (fr) * 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
AU2008356840B2 (en) 2008-05-22 2013-05-16 Centre National De La Recherche Scientifique (Cnrs) New optically pure compounds for improved therapeutic efficiency
CA2813665A1 (fr) 2010-10-04 2012-04-12 Elro Pharma Compositions comprenant des ligands synthetiques polyvalents de glycosaminoglycanes et de nucleoline

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707170A1 (fr) * 1993-06-04 1995-01-13 Pasteur Institut Expression des récepteurs CD4 et CD26 dans des cellules recombinantes, inhibiteurs du récepteur CD26.
IL110929A0 (en) * 1993-09-13 1994-11-28 Armel Sa Multiple branch peptide constructions and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0756603A1 (fr) 1997-02-05
WO1995029190A1 (fr) 1995-11-02
FR2719049A1 (fr) 1995-10-27
CA2188470A1 (fr) 1995-11-02
JPH10502337A (ja) 1998-03-03
FR2719049B1 (fr) 1996-06-14

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