AU2093297A - Use of 5-ht1a receptor antagonists for the treatment of urinary incontinence - Google Patents
Use of 5-ht1a receptor antagonists for the treatment of urinary incontinenceInfo
- Publication number
- AU2093297A AU2093297A AU20932/97A AU2093297A AU2093297A AU 2093297 A AU2093297 A AU 2093297A AU 20932/97 A AU20932/97 A AU 20932/97A AU 2093297 A AU2093297 A AU 2093297A AU 2093297 A AU2093297 A AU 2093297A
- Authority
- AU
- Australia
- Prior art keywords
- treatment
- ht1a receptor
- ht1a
- affinity
- receptor antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 title abstract 3
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 title abstract 3
- 206010046543 Urinary incontinence Diseases 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000017911 HTR1A Human genes 0.000 abstract 1
- 101150015707 HTR1A gene Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000026723 Urinary tract disease Diseases 0.000 abstract 1
- 102000030619 alpha-1 Adrenergic Receptor Human genes 0.000 abstract 1
- 108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000001242 postsynaptic effect Effects 0.000 abstract 1
- 230000003518 presynaptic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003727 serotonin 1A antagonist Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000014001 urinary system disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Spinning Or Twisting Of Yarns (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI96A0378 | 1996-02-28 | ||
| IT96MI000378A IT1282705B1 (it) | 1996-02-28 | 1996-02-28 | Uso di antagonisti del recettore serotoninergico 5-ht|a per il trattamento dell'incontinenza urinaria |
| PCT/EP1997/000897 WO1997031637A1 (en) | 1996-02-28 | 1997-02-25 | Use of 5-ht1a receptor antagonists for the treatment of urinary incontinence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2093297A true AU2093297A (en) | 1997-09-16 |
Family
ID=11373430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU20932/97A Abandoned AU2093297A (en) | 1996-02-28 | 1997-02-25 | Use of 5-ht1a receptor antagonists for the treatment of urinary incontinence |
Country Status (10)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6156780A (en) * | 1996-10-17 | 2000-12-05 | Milkhaus Laboratory, Inc. | Treatment of fecal incontinence |
| SE510305C2 (sv) | 1997-05-30 | 1999-05-10 | Astra Ab | Nytt salt |
| AU8130298A (en) * | 1997-07-15 | 1999-02-10 | Sankyo Company Limited | Piperazine derivatives |
| US6906069B1 (en) | 1999-01-08 | 2005-06-14 | Amgen Inc. | LXR modulators |
| WO2001060818A1 (en) * | 2000-02-14 | 2001-08-23 | Tularik Inc. | Lxr modulators |
| US6673543B2 (en) | 2000-04-05 | 2004-01-06 | Tularik, Inc. | Solid phase synthesis of LXR ligands |
| WO2002066468A2 (en) * | 2001-02-16 | 2002-08-29 | Aventis Pharmaceuticals Inc. | Heterocyclic urea derivatives and their use as dopamine d3 receptor ligands |
| BR0212824A (pt) * | 2001-09-27 | 2004-10-13 | Pharmacia Ab | Composição farmacêutica |
| JP4434745B2 (ja) | 2002-01-30 | 2010-03-17 | アムジェン インコーポレイテッド | 複素環式アリールスルホンアミドベンジル化合物 |
| CL2004000826A1 (es) | 2003-04-25 | 2005-03-04 | Pfizer | Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129 |
| US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| JPWO2006082872A1 (ja) * | 2005-02-04 | 2008-06-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | １−（ピペリジン−４−イル）−１ｈ−インドール誘導体 |
| JP4932717B2 (ja) | 2005-05-11 | 2012-05-16 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピペリジン環を有するインドール誘導体の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
| SG65570A1 (en) * | 1992-02-25 | 1999-06-22 | Recordati Chem Pharm | Heterobicyclic compounds |
| GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
| GB9417135D0 (en) * | 1994-08-23 | 1994-10-12 | Medinnova S F | Method |
-
1996
- 1996-02-28 IT IT96MI000378A patent/IT1282705B1/it active IP Right Grant
-
1997
- 1997-02-25 DE DE69727378T patent/DE69727378T2/de not_active Revoked
- 1997-02-25 PT PT97906125T patent/PT906100E/pt unknown
- 1997-02-25 JP JP53057997A patent/JP2001511763A/ja not_active Ceased
- 1997-02-25 AU AU20932/97A patent/AU2093297A/en not_active Abandoned
- 1997-02-25 WO PCT/EP1997/000897 patent/WO1997031637A1/en active Search and Examination
- 1997-02-25 ES ES97906125T patent/ES2213205T3/es not_active Expired - Lifetime
- 1997-02-25 DK DK97906125T patent/DK0906100T3/da active
- 1997-02-25 AT AT97906125T patent/ATE258438T1/de not_active IP Right Cessation
- 1997-02-25 EP EP97906125A patent/EP0906100B1/en not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997031637A1 (en) | 1997-09-04 |
| DE69727378T2 (de) | 2004-12-09 |
| JP2001511763A (ja) | 2001-08-14 |
| ITMI960378A1 (it) | 1997-08-28 |
| PT906100E (pt) | 2004-06-30 |
| ES2213205T3 (es) | 2004-08-16 |
| DK0906100T3 (da) | 2004-05-03 |
| ATE258438T1 (de) | 2004-02-15 |
| ITMI960378A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-02-28 |
| IT1282705B1 (it) | 1998-03-31 |
| EP0906100A1 (en) | 1999-04-07 |
| EP0906100B1 (en) | 2004-01-28 |
| DE69727378D1 (de) | 2004-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU9648098A (en) | Adenosine a3 receptor antagonists | |
| AU2093297A (en) | Use of 5-ht1a receptor antagonists for the treatment of urinary incontinence | |
| AU7406596A (en) | Heterocyclic compounds having tachykinin receptor antagonist activity, their preparation and their use | |
| EA199800340A1 (ru) | Производные пиримидина как антагонисты 5нт2с | |
| AU2337097A (en) | Meta-substituted phenylene derivatives and their use as alphavbeta3 integrin antagonists or inhibitors | |
| HU9601282D0 (en) | Phenyl-alkyl imidazoles as h3-receptor antagonists | |
| AU2337197A (en) | Cinnamic acid derivatives and their use as integrin antagonists | |
| EP1762236A3 (en) | Formulations of alpha adrenergic receptor antagonists and their uses | |
| DE69528823D1 (en) | Morpholinwirkstoffvorläufer als tachykininreceptorantagonisten | |
| AU2420897A (en) | Meta-substituted phenylene sulphonamide derivatives | |
| CA2133106A1 (en) | Monoclonal antibodies against the interferon receptor, with neutralizing activity against type i interferon | |
| EP2298298A3 (en) | Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors | |
| DK1129091T3 (da) | Antagonister for CRF-receptorer og fremgangsmåder med relation dertil | |
| AU4552497A (en) | Novel carboxylic acid derivatives, their preparation and use as mixed eta/etb receptor antagonists | |
| AU1667500A (en) | N-(2-phenyl-4-piperidinybutyl)-5,6,7,8-tetrahydro-1-naphthal necarboxamides and their use as neurokinin 1 (nk1) and/or neurokinin 2 (nk2) receptor antagonists | |
| MX9800483A (es) | Derivados de piperazina y su uso como antagonistas de 5-ht1a. | |
| WO1997031655A3 (en) | Modified cytokines for therapeutic use | |
| PL312959A1 (en) | Derivatives of bicyclo [2.2.2] octane exhibiting antagonistic action in respect to cholecystokinin and/or gastrin | |
| IT1255461B (it) | Eteri di imidazoli ad attivita' a ii antagonista | |
| SE9400809D0 (sv) | New use of quinoline-3-carboxamide compounds | |
| AU5627194A (en) | New use of 5-ht3 receptor antagonists | |
| AU2001263329A1 (en) | Crf receptor antagonists and methods relating thereto | |
| ES2106683A1 (es) | Derivados de 1,3-dioxoperhidropirido (1,2-c) pirimidinas como antagonistas de colecistoquinina. | |
| DE59408441D1 (de) | Substituierte 1-Phenyl-oxazolidin-2-on Derivate, deren Herstellung und deren Verwendung als Adhäsionsrezeptor-Antagonisten | |
| EA199800204A1 (ru) | Антагонисты 5-нтрецепторов для лечения дискинезии |