AU2023277730A1 - Oligonucleotides conjugated to oleic acid and uses thereof - Google Patents
Oligonucleotides conjugated to oleic acid and uses thereof Download PDFInfo
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- AU2023277730A1 AU2023277730A1 AU2023277730A AU2023277730A AU2023277730A1 AU 2023277730 A1 AU2023277730 A1 AU 2023277730A1 AU 2023277730 A AU2023277730 A AU 2023277730A AU 2023277730 A AU2023277730 A AU 2023277730A AU 2023277730 A1 AU2023277730 A1 AU 2023277730A1
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- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 title claims abstract description 163
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- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 title claims abstract description 34
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22382493.9 | 2022-05-23 | ||
| EP22382493.9A EP4282964A1 (en) | 2022-05-23 | 2022-05-23 | Oligonucleotides conjugated to oleic acid and uses thereof |
| PCT/EP2023/063829 WO2023227622A1 (en) | 2022-05-23 | 2023-05-23 | Oligonucleotides conjugated to oleic acid and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2023277730A1 true AU2023277730A1 (en) | 2025-01-02 |
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ID=81941129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2023277730A Pending AU2023277730A1 (en) | 2022-05-23 | 2023-05-23 | Oligonucleotides conjugated to oleic acid and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12116575B2 (https=) |
| EP (3) | EP4282964A1 (https=) |
| JP (2) | JP2025522282A (https=) |
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| WO2025114442A1 (en) * | 2023-11-28 | 2025-06-05 | Arthex Biotech S.L. | Oligonucleotides conjugated to oleic acid and uses thereof |
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| US7683036B2 (en) * | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| US10077443B2 (en) * | 2012-11-15 | 2018-09-18 | Roche Innovation Center Copenhagen A/S | Oligonucleotide conjugates |
| ES3047792T3 (en) * | 2014-07-14 | 2025-12-04 | Univ California | Crispr/cas transcriptional modulation |
| WO2016201272A1 (en) * | 2015-06-12 | 2016-12-15 | King Abdulaziz City For Science And Technology | Method of diagnosing patients with conditions caused by mendelian mutations |
| JP7511326B2 (ja) * | 2015-10-09 | 2024-07-05 | ウェイブ ライフ サイエンシズ リミテッド | オリゴヌクレオチド組成物およびその方法 |
| ES2659845B1 (es) | 2016-09-19 | 2019-01-04 | Univ Valencia | Modulación de microRNAs contra la distrofia miotónica tipo 1 y antagonistas de microRNAs para ello |
| TW202019441A (zh) * | 2018-07-20 | 2020-06-01 | 美商雷格勒斯治療公司 | 用於經口遞送寡核苷酸之方法 |
| EP4081302A4 (en) | 2019-12-23 | 2025-01-29 | University Of Massachusetts | OLIGONUCLEOTIDES FOR TISSUE-SPECIFIC GENE EXPRESSION MODULATION |
| EP4282964A1 (en) * | 2022-05-23 | 2023-11-29 | Universitat de Valéncia | Oligonucleotides conjugated to oleic acid and uses thereof |
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| US20230407305A1 (en) | 2023-12-21 |
| TW202411424A (zh) | 2024-03-16 |
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| CN119816594A (zh) | 2025-04-11 |
| EP4282964A1 (en) | 2023-11-29 |
| JP2023172954A (ja) | 2023-12-06 |
| IL317141A (en) | 2025-01-01 |
| CA3255781A1 (en) | 2023-11-30 |
| EP4486891A1 (en) | 2025-01-08 |
| WO2023227622A1 (en) | 2023-11-30 |
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