AU2021247253A1 - Use of exosome-based delivery of NF-κB inhibitors - Google Patents
Use of exosome-based delivery of NF-κB inhibitors Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
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- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| KR20200039011 | 2020-03-31 | ||
| KR10-2020-0039011 | 2020-03-31 | ||
| US202063112154P | 2020-11-10 | 2020-11-10 | |
| US63/112,154 | 2020-11-10 | ||
| US202063112155P | 2020-11-11 | 2020-11-11 | |
| US63/112,155 | 2020-11-11 | ||
| PCT/IB2021/052708 WO2021198961A1 (en) | 2020-03-31 | 2021-03-31 | Use of exosome-based delivery of nf-kb inhibitors |
Publications (1)
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| AU2021247253A1 true AU2021247253A1 (en) | 2022-10-20 |
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| AU2021247253A Pending AU2021247253A1 (en) | 2020-03-31 | 2021-03-31 | Use of exosome-based delivery of NF-κB inhibitors |
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| EP (1) | EP4127136A4 (ja) |
| JP (1) | JP7498293B2 (ja) |
| KR (2) | KR20220149781A (ja) |
| CN (1) | CN115335079A (ja) |
| AU (1) | AU2021247253A1 (ja) |
| CA (1) | CA3173845A1 (ja) |
| WO (1) | WO2021198961A1 (ja) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115212234B (zh) * | 2021-10-22 | 2023-11-10 | 武汉大学中南医院 | 纤维网状细胞来源的外泌体在制备用于治疗和/或预防脓毒症急性肾损伤的药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| SG11201508433TA (en) * | 2013-04-12 | 2015-11-27 | Andaloussi Samir El | Therapeutic delivery vesicles |
| WO2018062973A1 (en) * | 2016-09-30 | 2018-04-05 | Cellex Life Sciences, Incorporated | Compositions containing protein loaded exosome and methods for preparing and delivering the same |
| KR101877010B1 (ko) * | 2016-09-30 | 2018-08-09 | 한국과학기술원 | super-repressor-IκB 단백질을 포함하는 엑소솜의 제조 방법 및 상기 제조 방법에 의해 제조된 엑소솜을 유효성분으로 함유하는 염증성 질환 예방 및 치료용 약학적 조성물 |
| JP2019535839A (ja) * | 2016-11-29 | 2019-12-12 | ピュアテック ヘルス エルエルシー | 治療剤の送達のためのエクソソーム |
| CN107158390A (zh) * | 2017-07-12 | 2017-09-15 | 上海市东方医院 | 组蛋白去乙酰化酶hdac6的抑制剂在制备防治急性肾损伤药物中的用途 |
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2021
- 2021-03-31 KR KR1020227034736A patent/KR20220149781A/ko active Application Filing
- 2021-03-31 JP JP2022559527A patent/JP7498293B2/ja active Active
- 2021-03-31 KR KR1020217014385A patent/KR20210124180A/ko active Application Filing
- 2021-03-31 CA CA3173845A patent/CA3173845A1/en active Pending
- 2021-03-31 WO PCT/IB2021/052708 patent/WO2021198961A1/en unknown
- 2021-03-31 EP EP21781109.0A patent/EP4127136A4/en active Pending
- 2021-03-31 CN CN202180024099.7A patent/CN115335079A/zh active Pending
- 2021-03-31 AU AU2021247253A patent/AU2021247253A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3173845A1 (en) | 2021-10-07 |
| KR20210124180A (ko) | 2021-10-14 |
| EP4127136A4 (en) | 2024-04-03 |
| WO2021198961A1 (en) | 2021-10-07 |
| JP2023519700A (ja) | 2023-05-12 |
| KR20220149781A (ko) | 2022-11-08 |
| EP4127136A1 (en) | 2023-02-08 |
| CN115335079A (zh) | 2022-11-11 |
| JP7498293B2 (ja) | 2024-06-11 |
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