AU2020296181A1 - Use of bispecific antigen-binding molecules that bind PSMA and CD3 in combination with 4-1BB co-stimulation - Google Patents

Use of bispecific antigen-binding molecules that bind PSMA and CD3 in combination with 4-1BB co-stimulation Download PDF

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Publication number
AU2020296181A1
AU2020296181A1 AU2020296181A AU2020296181A AU2020296181A1 AU 2020296181 A1 AU2020296181 A1 AU 2020296181A1 AU 2020296181 A AU2020296181 A AU 2020296181A AU 2020296181 A AU2020296181 A AU 2020296181A AU 2020296181 A1 AU2020296181 A1 AU 2020296181A1
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Prior art keywords
psma
antigen
binding
antibody
tumor
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AU2020296181A
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Inventor
Danica CHIU
Alison CRAWFORD
Jessica R. Kirshner
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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AU2020296181A 2019-06-21 2020-06-19 Use of bispecific antigen-binding molecules that bind PSMA and CD3 in combination with 4-1BB co-stimulation Pending AU2020296181A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962864999P 2019-06-21 2019-06-21
US62/864,999 2019-06-21
PCT/US2020/038786 WO2020257681A1 (en) 2019-06-21 2020-06-19 Use of bispecific antigen-binding molecules that bind psma and cd3 in combination with 4-1bb co-stimulation

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AU2020296181A1 true AU2020296181A1 (en) 2021-12-16

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US (1) US20200399372A1 (enExample)
EP (1) EP3986933A1 (enExample)
JP (2) JP7743313B2 (enExample)
KR (1) KR20220024594A (enExample)
CN (2) CN118526580A (enExample)
AU (1) AU2020296181A1 (enExample)
CA (1) CA3139827A1 (enExample)
IL (1) IL289041A (enExample)
MA (1) MA56515A (enExample)
MX (1) MX2021015271A (enExample)
WO (1) WO2020257681A1 (enExample)
ZA (1) ZA202109048B (enExample)

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KR20240139065A (ko) * 2022-02-07 2024-09-20 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 Psma 및 cd3에 특이적으로 결합하는 항원 결합 분자 및 이들의 의약적 용도
WO2023224912A1 (en) * 2022-05-16 2023-11-23 Regeneron Pharmaceuticals, Inc. Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
WO2025070636A1 (ja) * 2023-09-26 2025-04-03 ブライトパス・バイオ株式会社 Ｃｄ３９を標的とする多重特異性抗原結合性分子
CN118086511B (zh) * 2024-04-25 2024-07-09 中国中医科学院望京医院(中国中医科学院骨伤科研究所) 胃粘膜肠上皮化生亚型生物标志物folh1及其应用

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