AU2020273183A1 - Methods and materials for gender-dependent treatment of cardiovascular dysfunction - Google Patents

Methods and materials for gender-dependent treatment of cardiovascular dysfunction Download PDF

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Publication number
AU2020273183A1
AU2020273183A1 AU2020273183A AU2020273183A AU2020273183A1 AU 2020273183 A1 AU2020273183 A1 AU 2020273183A1 AU 2020273183 A AU2020273183 A AU 2020273183A AU 2020273183 A AU2020273183 A AU 2020273183A AU 2020273183 A1 AU2020273183 A1 AU 2020273183A1
Authority
AU
Australia
Prior art keywords
mammal
bay
iwp
female
male
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2020273183A
Other languages
English (en)
Inventor
Maurice E. ENRIQUEZ-SARANO
Jordan D. Miller
Carolyn Marie ROOS
Bin Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Clinic in Florida
Original Assignee
Mayo Foundation for Medical Education and Research
Mayo Clinic in Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation for Medical Education and Research, Mayo Clinic in Florida filed Critical Mayo Foundation for Medical Education and Research
Publication of AU2020273183A1 publication Critical patent/AU2020273183A1/en
Priority to AU2025256169A priority Critical patent/AU2025256169A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2020273183A 2019-04-10 2020-04-10 Methods and materials for gender-dependent treatment of cardiovascular dysfunction Abandoned AU2020273183A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025256169A AU2025256169A1 (en) 2019-04-10 2025-10-23 Methods and materials for gender-dependent treatment of cardiovascular dysfunction

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962832139P 2019-04-10 2019-04-10
US62/832,139 2019-04-10
PCT/US2020/027777 WO2020210707A1 (en) 2019-04-10 2020-04-10 Methods and materials for gender-dependent treatment of cardiovascular dysfunction

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025256169A Division AU2025256169A1 (en) 2019-04-10 2025-10-23 Methods and materials for gender-dependent treatment of cardiovascular dysfunction

Publications (1)

Publication Number Publication Date
AU2020273183A1 true AU2020273183A1 (en) 2021-10-14

Family

ID=72752121

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2020273183A Abandoned AU2020273183A1 (en) 2019-04-10 2020-04-10 Methods and materials for gender-dependent treatment of cardiovascular dysfunction
AU2025256169A Pending AU2025256169A1 (en) 2019-04-10 2025-10-23 Methods and materials for gender-dependent treatment of cardiovascular dysfunction

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025256169A Pending AU2025256169A1 (en) 2019-04-10 2025-10-23 Methods and materials for gender-dependent treatment of cardiovascular dysfunction

Country Status (11)

Country Link
US (1) US12465605B2 (https=)
EP (1) EP3952992A4 (https=)
JP (2) JP2022526621A (https=)
KR (1) KR20210150495A (https=)
CN (1) CN114144229A (https=)
AU (2) AU2020273183A1 (https=)
CA (1) CA3136550A1 (https=)
IL (1) IL287073A (https=)
MX (2) MX2021012409A (https=)
SG (1) SG11202110533RA (https=)
WO (1) WO2020210707A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117357506A (zh) * 2023-09-11 2024-01-09 重庆医科大学国际体外诊断研究院 丹酚酸a在治疗钙化性主动脉瓣膜疾病中的用途
CN117969836B (zh) * 2024-03-29 2024-06-04 北京市心肺血管疾病研究所 基于血浆炎症蛋白构建主动脉瓣钙化狭窄诊断模型及应用

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US6723719B1 (en) 1997-04-25 2004-04-20 Pfizer Inc Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3′,5′—monophosphate phosphodiesterase (cGMP PDE5) for the treatment of sexual dysfunction
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Also Published As

Publication number Publication date
SG11202110533RA (en) 2021-10-28
MX2021012409A (es) 2021-11-12
MX2024010759A (es) 2024-09-10
WO2020210707A1 (en) 2020-10-15
EP3952992A4 (en) 2023-04-19
JP2025172729A (ja) 2025-11-26
AU2025256169A1 (en) 2025-11-13
JP2022526621A (ja) 2022-05-25
KR20210150495A (ko) 2021-12-10
US12465605B2 (en) 2025-11-11
US20220211702A1 (en) 2022-07-07
EP3952992A1 (en) 2022-02-16
IL287073A (en) 2021-12-01
CN114144229A (zh) 2022-03-04
CA3136550A1 (en) 2020-10-15

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted