AU2003286555A1 - Phosphodiester inhibitors and nitric oxide modulators for treating peyronie's disease, arteriosclerosis and other fibrotic diseases - Google Patents

Phosphodiester inhibitors and nitric oxide modulators for treating peyronie's disease, arteriosclerosis and other fibrotic diseases

Info

Publication number
AU2003286555A1
AU2003286555A1 AU2003286555A AU2003286555A AU2003286555A1 AU 2003286555 A1 AU2003286555 A1 AU 2003286555A1 AU 2003286555 A AU2003286555 A AU 2003286555A AU 2003286555 A AU2003286555 A AU 2003286555A AU 2003286555 A1 AU2003286555 A1 AU 2003286555A1
Authority
AU
Australia
Prior art keywords
arteriosclerosis
disease
nitric oxide
fibrotic diseases
oxide modulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003286555A
Other versions
AU2003286555A8 (en
Inventor
Nestor F. Gonzalez-Cadavid
Jacob Rajfer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HARBOR-UCLA RESEARCH AND EDUCATION INSTITUTE
Original Assignee
HARBOR-UCLA RESEARCH AND EDUCATION INSTITUTE
Harbor UCLA Research and Education Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HARBOR-UCLA RESEARCH AND EDUCATION INSTITUTE, Harbor UCLA Research and Education Institute filed Critical HARBOR-UCLA RESEARCH AND EDUCATION INSTITUTE
Publication of AU2003286555A1 publication Critical patent/AU2003286555A1/en
Publication of AU2003286555A8 publication Critical patent/AU2003286555A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
AU2003286555A 2002-10-22 2003-10-21 Phosphodiester inhibitors and nitric oxide modulators for treating peyronie's disease, arteriosclerosis and other fibrotic diseases Abandoned AU2003286555A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42028102P 2002-10-22 2002-10-22
US60/420,281 2002-10-22
PCT/US2003/033400 WO2004037183A2 (en) 2002-10-22 2003-10-21 Phosphodiester inhibitors and nitric oxide modulators for treating peyronie’s disease, arteriosclerosis and other fibrotic diseases

Publications (2)

Publication Number Publication Date
AU2003286555A1 true AU2003286555A1 (en) 2004-05-13
AU2003286555A8 AU2003286555A8 (en) 2004-05-13

Family

ID=32176545

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003286555A Abandoned AU2003286555A1 (en) 2002-10-22 2003-10-21 Phosphodiester inhibitors and nitric oxide modulators for treating peyronie's disease, arteriosclerosis and other fibrotic diseases

Country Status (2)

Country Link
AU (1) AU2003286555A1 (en)
WO (1) WO2004037183A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038328A1 (en) * 2004-08-06 2006-03-16 Bayer Healthcare Ag New uses of 2-phenyl-substituted imidazotriazinone derivatives
CA2577442A1 (en) 2004-08-17 2006-03-02 The Johns Hopkins University Pde5 inhibitor compositions and methods for treating cardiac indications
TWI339578B (en) 2004-10-29 2011-04-01 Mitsubishi Tanabe Pharma Corp Use of a pyridine compound for the preparation of a medicament for the treatment of skin lesions
UA86528C2 (en) * 2005-06-10 2009-04-27 Донг-А Фармацевтікал.Ко., Лтд. composition for prevention and treatment of liver diseases containing pyrazolopyrimidine derivative
CA2704100C (en) * 2007-10-26 2017-07-04 Pacific Therapeutics Ltd. Compositions and methods for treating fibroproliferative disorders
RU2625726C2 (en) 2011-07-20 2017-07-18 Медиваунд Лтд. Bromelain extract with proteolytic activity to treat connective tissue diseases
WO2014100733A1 (en) 2012-12-21 2014-06-26 Mayo Foundation For Medical Education And Research Methods and materials for treating calcific aortic valve stenosis
JP2018505156A (en) * 2015-01-06 2018-02-22 インプリミス・ファーマシューティカルズ・インコーポレイテッドＩｍｐｒｉｍｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． Pharmaceutical formulation of xanthine or xanthine derivative
EP3595623B1 (en) 2017-03-14 2024-05-01 Atir Holding S.A. Topical formulation for the treatment of pigmented skin
US11033549B2 (en) 2017-03-14 2021-06-15 Atir Holding S.A. Use of heterocyclic compounds in the treatment of pigmented skin
CN112773898A (en) * 2019-11-11 2021-05-11 广州华真医药科技有限公司 Application of phosphodiesterase 5 inhibitor in preparing anti-fibrosis disease medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430128A1 (en) * 1994-08-25 1996-02-29 Hoechst Ag Combination preparation with immunosuppressive, cardiovascular and cerebral effects
US5731339A (en) * 1995-04-28 1998-03-24 Zonagen, Inc. Methods and formulations for modulating the human sexual response
US5824669A (en) * 1996-03-22 1998-10-20 Nitromed, Inc. Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders

Also Published As

Publication number Publication date
WO2004037183A3 (en) 2004-08-05
WO2004037183A2 (en) 2004-05-06
AU2003286555A8 (en) 2004-05-13

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase