AU2020242062B2 - Coatings for gastric residence dosage forms - Google Patents

Coatings for gastric residence dosage forms

Info

Publication number
AU2020242062B2
AU2020242062B2 AU2020242062A AU2020242062A AU2020242062B2 AU 2020242062 B2 AU2020242062 B2 AU 2020242062B2 AU 2020242062 A AU2020242062 A AU 2020242062A AU 2020242062 A AU2020242062 A AU 2020242062A AU 2020242062 B2 AU2020242062 B2 AU 2020242062B2
Authority
AU
Australia
Prior art keywords
gastric residence
enrobed
dosage form
coating
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2020242062A
Other languages
English (en)
Other versions
AU2020242062A1 (en
Inventor
David Altreuter
Nupura BHISE
Tyler GRANT
Sonia HOLAR
Rosemary KANASTY
Erick PEEKE
Marlene Schwarz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nortiva Bio Inc
Original Assignee
Nortiva Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nortiva Bio Inc filed Critical Nortiva Bio Inc
Publication of AU2020242062A1 publication Critical patent/AU2020242062A1/en
Application granted granted Critical
Publication of AU2020242062B2 publication Critical patent/AU2020242062B2/en
Assigned to Nortiva Bio, Inc. reassignment Nortiva Bio, Inc. Request for Assignment Assignors: LYNDRA THERAPEUTICS, INC.
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
AU2020242062A 2019-03-20 2020-03-19 Coatings for gastric residence dosage forms Active AU2020242062B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962821361P 2019-03-20 2019-03-20
US62/821,361 2019-03-20
PCT/US2020/023710 WO2020191231A1 (en) 2019-03-20 2020-03-19 Coatings for gastric residence dosage forms

Publications (2)

Publication Number Publication Date
AU2020242062A1 AU2020242062A1 (en) 2021-11-11
AU2020242062B2 true AU2020242062B2 (en) 2025-12-11

Family

ID=72519158

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020242062A Active AU2020242062B2 (en) 2019-03-20 2020-03-19 Coatings for gastric residence dosage forms

Country Status (10)

Country Link
US (1) US12582608B2 (enExample)
EP (1) EP3941444B1 (enExample)
JP (2) JP2022525482A (enExample)
CN (1) CN113840596A (enExample)
AU (1) AU2020242062B2 (enExample)
BR (1) BR112021018424A2 (enExample)
CA (1) CA3134186A1 (enExample)
IL (1) IL286510A (enExample)
MX (1) MX2021011310A (enExample)
WO (1) WO2020191231A1 (enExample)

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WO2020117855A1 (en) 2018-12-03 2020-06-11 Lyndra, Inc. Stomach simulating device
BR112021018496A2 (pt) 2019-03-20 2021-11-30 Lyndra Therapeutics Inc Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica
AU2020242062B2 (en) 2019-03-20 2025-12-11 Nortiva Bio, Inc. Coatings for gastric residence dosage forms
JP7847119B2 (ja) 2020-07-29 2026-04-16 ザ・セカント・グループ・エルエルシー 架橋ポリ（セバシン酸グリセロール）を含む構造を含む形状誘導型制御放出および保持
WO2024225479A1 (ja) * 2023-04-28 2024-10-31 クオリカプス株式会社 バンドシール液、バンドシール、ゼラチン硬質カプセルの封緘方法、及びゼラチン硬質カプセル製品

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US6200603B1 (en) * 1997-03-25 2001-03-13 R. P. Scherer Corporation Comestible capsules having flavored coatings
US20090304768A1 (en) * 2006-02-15 2009-12-10 Intec Pharma Ltd Gastro-Retentive System for the Delivery of Macromolecules
WO2010064100A1 (en) * 2008-12-04 2010-06-10 Intec Pharma Ltd. Baclofen gastroretentive drug delivery system
US20150366815A1 (en) * 2014-06-20 2015-12-24 Banner Life Sciences Llc Enteric soft capsule compositions

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IL166183A0 (en) 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
KR20080005429A (ko) * 2005-04-19 2008-01-11 알자 코포레이션 트라마돌 및 가바펜틴을 포함하는 물질의 배합물
WO2007002518A1 (en) 2005-06-23 2007-01-04 Spherics, Inc. Delayed release or extended-delayed release dosage forms of pramipexole
JP4948828B2 (ja) 2005-11-28 2012-06-06 森下仁丹株式会社 胃内浮遊滞留シームレスカプセルとその製造方法
CA2675230A1 (en) 2006-01-10 2008-07-26 Pipex, Inc. Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
EP2997953B1 (en) 2006-01-18 2018-12-26 Intec Pharma Ltd. Delivery device for oral intake of an agent
JP2012500230A (ja) * 2008-08-18 2012-01-05 北京天衡▲薬▼物研究院 胃内滞留薬物放出システム及びその製造方法と使用
US8006033B2 (en) 2008-09-09 2011-08-23 Intel Corporation Systems, methods, and apparatuses for in-band data mask bit transmission
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EP2490677A2 (en) 2009-10-19 2012-08-29 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
CA2825917C (en) 2011-02-14 2016-08-30 The Procter & Gamble Company Filmcoated solid dosage forms comprising honey in the coating
WO2014035639A1 (en) 2012-08-29 2014-03-06 Cardiac Pacemakers, Inc. Enhanced low friction coating for medical leads and methods of making
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NZ727659A (en) 2014-06-11 2021-12-24 Massachusetts Inst Technology Residence structures and related methods
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
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MX387092B (es) 2015-06-17 2025-03-19 Biogen Ma Inc Particulas de dimetilfumarato y composiciones farmaceuticas de estas.
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CN109310639A (zh) 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ，インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
CN110035718B (zh) * 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
CA3066658A1 (en) 2017-06-09 2018-12-13 Lyndra, Inc. Gastric residence systems with release rate-modulating films
US11793751B2 (en) 2017-09-20 2023-10-24 Lyndra Therapeutics, Inc. Encapsulation of gastric residence systems
JP2021535090A (ja) 2018-08-15 2021-12-16 リンドラ セラピューティクス， インコーポレイティド 治療薬物の腸内送達のためのシステム
WO2020117855A1 (en) 2018-12-03 2020-06-11 Lyndra, Inc. Stomach simulating device
AU2020242062B2 (en) 2019-03-20 2025-12-11 Nortiva Bio, Inc. Coatings for gastric residence dosage forms
BR112021018496A2 (pt) 2019-03-20 2021-11-30 Lyndra Therapeutics Inc Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica
WO2021092486A1 (en) 2019-11-08 2021-05-14 Lyndra, Inc. Formulations for release-rate modulating films for gastric residence systems
IL292848A (en) 2019-11-08 2022-07-01 Lyndra Therapeutics Inc Polymeric linkers for a gastric residence system
JP2022553867A (ja) 2019-11-08 2022-12-26 リンドラ セラピューティクス， インコーポレイティド 胃内滞留を改善するフィラメントを有する胃内滞留システム
MX2022005494A (es) 2019-11-08 2022-08-11 Lyndra Therapeutics Inc Sistemas de residencia gastrica para la administracion de agentes activos.
US20220387312A1 (en) 2019-11-08 2022-12-08 Lyndra Therapeutics, Inc. Gastric residence systems having arms with controlled stiffness for improved gastric residence
US20240390270A1 (en) 2021-01-19 2024-11-28 Lyndra Therapeutics, Inc. Gastric residence systems for administration of risperidone
JP2024517829A (ja) 2021-05-05 2024-04-23 リンドラ セラピューティクス， インコーポレイティド メタドンを含む胃内滞留システム
WO2022236288A1 (en) 2021-05-05 2022-11-10 Lyndra Therapeutics, Inc. Gastric residence systems comprising buprenorphine and naloxone
AU2023209872A1 (en) 2022-01-19 2024-08-01 Nortiva Bio, Inc. Dosage forms for gastric retention
CN120091832A (zh) 2022-08-03 2025-06-03 林德拉治疗公司 用于胃驻留系统的金属芯部
JP2025531626A (ja) 2022-09-30 2025-09-22 リンドラ セラピューティクス， インコーポレイティド 胃内滞留システムを用いたリスペリドンの投与レジメン
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200603B1 (en) * 1997-03-25 2001-03-13 R. P. Scherer Corporation Comestible capsules having flavored coatings
US20090304768A1 (en) * 2006-02-15 2009-12-10 Intec Pharma Ltd Gastro-Retentive System for the Delivery of Macromolecules
WO2010064100A1 (en) * 2008-12-04 2010-06-10 Intec Pharma Ltd. Baclofen gastroretentive drug delivery system
US20150366815A1 (en) * 2014-06-20 2015-12-24 Banner Life Sciences Llc Enteric soft capsule compositions

Also Published As

Publication number Publication date
EP3941444A1 (en) 2022-01-26
CA3134186A1 (en) 2020-09-24
IL286510A (en) 2021-10-31
CN113840596A (zh) 2021-12-24
MX2021011310A (es) 2021-12-10
US20220192995A1 (en) 2022-06-23
BR112021018424A2 (pt) 2021-11-23
JP2025067914A (ja) 2025-04-24
EP3941444B1 (en) 2025-03-26
US12582608B2 (en) 2026-03-24
WO2020191231A1 (en) 2020-09-24
JP2022525482A (ja) 2022-05-16
AU2020242062A1 (en) 2021-11-11
EP3941444A4 (en) 2023-01-11

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: NORTIVA BIO, INC.

Free format text: FORMER APPLICANT(S): LYNDRA THERAPEUTICS, INC.

FGA Letters patent sealed or granted (standard patent)